Results 41 to 50 of about 943,525 (345)

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Influence of flexoelectric, small-scale, surface and residual stress on the nonlinear vibration of sigmoid, exponential and power-law FG Timoshenko nano-beams

Journal of Low Frequency Noise, Vibration and Active Control, 2019
This research deals with the nonlinear vibration of the functionally graded nano-beams based on the nonlocal elasticity theory considering surface and flexoelectric effects.
Mohammad Arefi, Mahmoud Pourjamshidian, Ali Ghorbanpour Arani, Timon Rabczuk   +3 more
doaj   +1 more source

Elasticity analysis of sandwich pipes with functionally graded interlayers [PDF]

, 2016
Acknowledgements Financial support of this research by the Royal Society of Edinburgh and the Italian Academy of Sciences under International Exchanges Bilateral Programme grant is gratefully acknowledged.Peer ...
Kashtalyan, Maria, Sburlati, Roberta
core   +1 more source

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

FEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva, Puspa Kunwar, Md Ibnul Rifat Rahman, Joanna Koryo Kwao, Nathan Lehman, Zihan Zhang, Trenton Paul, Claire Cheng, Nicholas Truex, Hui‐Ting Lee, Jun Zhang   +10 more
wiley   +1 more source

Boundary element method applied to the bending analysis of thin functionally graded plates

Latin American Journal of Solids and Structures
The present work introduces the boundary element method applied to the bending analysis of functionally graded plates. It is assumed that material properties are graded through the thickness direction of the plate according to a power law distribution ...
A. R. Damanpack, M. Bodaghi, H. Ghassemi, M. Sayehbani   +3 more
doaj   +1 more source

Three-dimensional free vibration analysis of thermally loaded fgm sandwich plates [PDF]

, 2020
Using the finite element code ABAQUS and the user-defined material utilities UMAT and UMATHT, a solid brick graded finite element is developed for three-dimensional (3D) modeling of free vibrations of thermally loaded functionally gradient material (FGM)
Burlayenko, V. N., Dimitrova, Svetlana, Sadowski, Tomasz   +2 more
core  

Three-dimensional elastic deformation of functionally graded isotropic plates under point loading [PDF]

, 2014
Acknowledgement Financial support of this research by The Royal Society (UK) under grant number JP090633 is gratefully acknowledged.Peer ...
Abali, B. E., Guz, I., Kashtalyan, M., Müller, W. H., Völlmecke, C., Woodward, B.   +5 more
core   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Computational modeling of sigmoid functionally graded material (SFGM) plate

Materials Research Express, 2023
The first-order shear deformation theory (FSDT) was used to explore the natural frequency response of functionally graded piezoelectric plates subjected to static electrical and mechanical strain in this present study.
Jai Kumar Sharma, Sateesh Kumar, Nishant Kumar, S M Mozammil Hasnain, Shatrudhan Pandey, Ahmed Farouk Deifalla, Adham E Ragab   +6 more
doaj   +1 more source

Elastoplastic stress analysis of functionally graded disc under internal pressure– complas XII [PDF]

, 2013
The study deals with elastoplastic stress analysis of a hollow disk made of functionally graded materials (FGMs) subjected to an internal pressure. The material properties of disc are assumed to vary radially according to power law function, but Poisson ...
Agir, I., Kursun, A., Topçu, M.
core