Results 61 to 70 of about 943,525 (345)
Molecular Oncology, EarlyView.Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice +16 more
wiley +1 more source
Energy capabilities of permeable thermoelectric coolers made of functionally graded materials
Технологія та конструювання в електронній апаратурі, 2004 A method is presented and results of computer design of permeable thermoelements made of functionally graded materials (FGM) for cooling a heat carrier blown through channels or pores in the branches are provided.
L. N. Vikhor, R. G. Cherkez
doaj
Engineering Transactions, 2014 In this paper geometrically nonlinear analysis of functionally graded shells in 6-parameter shell theory is presented. It is assumed that the shell consists of two constituents: ceramic and metal.
Karol DASZKIEWICZ +2 more
doaj +1 more source
On axisymmetric adhesive joints with graded interface stiffness
, 2013 An improved analytical model is presented for the stress analysis of interface stiffness graded axisymmetric adhesive joints. The governing integro-differential equation of the problem is obtained through a variational method which minimizes the ...
Kumar, S., Scanlan, J.P.
core +1 more source
Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells
Molecular Oncology, EarlyView.We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller +17 more
wiley +1 more source
Applied Sciences, 2022 This paper analyzes the sound radiation behavior of a clamped thin, functionally graded material plate using the classical plate theory and Rayleigh Integral with the elemental radiator approach.
Baij Nath Singh +5 more
doaj +1 more source
Multi-Material Ultrasonic Consolidation [PDF]
, 2006 Ultrasonic consolidation (UC) is a recently developed direct metal solid freeform fabrication process. While the process has been well-demonstrated for part fabrication in Al alloy 3003 H18, including with intricate cooling channels, some of the ...
Janaki Ram, G. D. +2 more
core +1 more source
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Molecular Oncology, EarlyView.Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
Fabrication of Functionally Graded Material (FGM) Set-Up [PDF]
, 2015 Functionally graded materials (FGMs) are advanced composites with graded properties that are novel concepts in the structural design of materials and have extensive applications in the aerospace engineering, aircrafts and automotive industry.
Sahoo, Deepak Kumar
core
Functionally Graded Media [PDF]
, 2007 The notions of uniformity and homogeneity of elastic materials are reviewed in terms of Lie groupoids and frame bundles. This framework is also extended to consider the case Functionally Graded Media, which allows us to obtain some homogeneity conditions.
Campos, Cedric M. +2 more
core +2 more sources