Results 61 to 70 of about 81,942 (347)

Multi-Material Ultrasonic Consolidation [PDF]

, 2006
Ultrasonic consolidation (UC) is a recently developed direct metal solid freeform fabrication process. While the process has been well-demonstrated for part fabrication in Al alloy 3003 H18, including with intricate cooling channels, some of the ...
Janaki Ram, G. D., Robinson, C., Stucker, B. E.   +2 more
core   +1 more source

Cell density–dependent nuclear‐cytoplasmic shuttling of SETDB1 integrates with Hippo signaling to regulate YAP1‐mediated transcription

FEBS Letters, EarlyView.
At low cell density, SETDB1 and YAP1 accumulate in the nucleus. As cell density increases, the Hippo pathway is gradually activated, and SETDB1 is associated with increased YAP1 phosphorylation. At high cell density, phosphorylated YAP1 is sequestered in the cytoplasm, while SETDB1 becomes polyubiquitinated and degraded by the ubiquitin–proteasome ...
Jaemin Eom, Jaewoong Jang, Jung Sun Park, Yong‐Kook Kang   +3 more
wiley   +1 more source

Torsion of Functionally Graded Material Structures: An Overview

Engineering Transactions
Examining torsion in functionally graded materials (FGMs) is crucial because their properties vary spatially. FGMs with continuously graded architectures provide a robust basis for investigating mechanical behavior.
Mateusz Kumor, Artur Ganczarski
doaj   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source

On axisymmetric adhesive joints with graded interface stiffness

, 2013
An improved analytical model is presented for the stress analysis of interface stiffness graded axisymmetric adhesive joints. The governing integro-differential equation of the problem is obtained through a variational method which minimizes the ...
Kumar, S., Scanlan, J.P.
core   +1 more source

Characterizing the salivary RNA landscape to identify potential diagnostic, prognostic, and follow‐up biomarkers for breast cancer

Molecular Oncology, EarlyView.
This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan, Irina Primac, Emre Etlioglu, Laurens Debruyne, Ann Janssen, Magy Sallam, Kevin Tabury, Roel Quintens, Wiebren Tjalma, Mohammed Abderrafi Benotmane   +9 more
wiley   +1 more source

Simulation and Validation of Three Dimension Functionally Graded Materials by Material Jetting [PDF]

, 2018
The goal of this work is to validate the material models for parts created with a Material Jetting 3-dimensional printer through the comparison of Finite Element Analysis (FEA) simulations and physical tests.
Baek, Dongcheon, Berndt, Aaron, Ryu, Jong Eun, Salcedo, Eduardo   +3 more
core   +1 more source

Adenosine‐to‐inosine editing of miR‐200b‐3p is associated with the progression of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
A‐to‐I editing of miRNAs, particularly miR‐200b‐3p, contributes to HGSOC progression by enhancing cancer cell proliferation, migration and 3D growth. The edited form is linked to poorer patient survival and the identification of novel molecular targets.
Magdalena Niemira, Anna Skwarska, Karolina Chwialkowska, Agnieszka Ostrowska, Gabriela Sokolowska, Anna Zeller, Anna Erol, Andrzej Eljaszewicz, Bartosz Hanczaruk, Anna Michalska‐Falkowska, Agnieszka Tarasik, Joanna Reszec‐Gielazyn, Pawel Knapp, Marcin Moniuszko, Adam Kretowski   +14 more
wiley   +1 more source

Fabrication of Functionally Graded Material (FGM) Set-Up [PDF]

, 2015
Functionally graded materials (FGMs) are advanced composites with graded properties that are novel concepts in the structural design of materials and have extensive applications in the aerospace engineering, aircrafts and automotive industry.
Sahoo, Deepak Kumar
core  

Experimental study on severe plastic deformation of Ti by novel equal-channel angular pressing [PDF]

, 2012
This study involves experimental investigation on severe plastic deformation (SPD) of Ti using novel equal-channel angular pressing (ECAP) at ambient temperature.
Fujiwara, Eri Miura, Jamian, Saifulnizan, Sato, Hisashi, Yoshimi, Watanabe   +3 more
core   +1 more source