Results 81 to 90 of about 75,347 (300)
Advances in Mechanical Engineering, 2019 This article investigates bending, buckling, and vibration analysis in viscoelastic functionally graded curved nanobeam embedded in an elastic medium under different boundary conditions.
Mohamed NM Allam, Ahmed F Radwan
doaj +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
Vibration Analysis of Functionally Graded Carbon Nanotube Reinforced Beam Structures [PDF]
, 2015 This work deals with the study of vibration behavior of the Functionally Graded Timoshenko Beam that has been reinforced with Carbon Nanotubes (CNTs), which is subjected to thermal and mechanical loads.
Kumar , Nitish
core
SFF-Oriented Modeling and Process Planning of Functionally Graded Materials Using a Novel Equal Distance Offset Approach [PDF]
, 2004 This paper deals with the modeling and process planning of solid freeform fabrication (SFF) of 3D functionally graded materials (FGMs). A novel approach of representation and process planning of FGMs, termed as equal distance offset (EDO), is developed.
Shaw, Leon L., Xu, Anping
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Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
Gradient design of metal hollow sphere (MHS) foams with density gradients [PDF]
, 2012 This is the post-print version of the final paper published in Composites Part B: Engineering. The published article is available from the link below. Changes resulting from the publishing process, such as peer review, editing, corrections, structural ...
Liu, Y, Wang, B, Wu, H-X
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Advances in Mechanical Engineering, 2015 A novel symplectic approach is employed in the analysis of homogenous and functionally graded beams subjected to arbitrary tractions on the lateral surfaces.
Li Zhao, Weizhong Gan
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Molecular Oncology, EarlyView.We show that the majority of the 18 analyzed recurrent cancer‐associated ERBB4 mutations are transforming. The most potent mutations are activating, co‐operate with other ERBB receptors, and are sensitive to pan‐ERBB inhibitors. Activating ERBB4 mutations also promote therapy resistance in EGFR‐mutant lung cancer.
Veera K. Ojala +15 more
wiley +1 more source
Thermo-mechanical analysis of carbon nanotube based functionally graded Timoshenko beam [PDF]
, 2014 This analytical work deals with prediction of the stresses developed in a Functionally Graded Timoshenko Beam that has been reinforced with Carbon Nanotubes (CNTs), which is subjected to thermal and mechanical loads.
Naik, K, Sahoo, S, Sahoo, S S
core
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source