Results 81 to 90 of about 1,795,694 (242)

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

open access: yesMolecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley   +5 more
wiley   +1 more source

Estimating Intrinsic Camera Parameters from the Fundamental Matrix Using an Evolutionary Approach

open access: yesEURASIP Journal on Advances in Signal Processing, 2004
Calibration is the process of computing the intrinsic (internal) camera parameters from a series of images. Normally calibration is done by placing predefined targets in the scene or by having special camera motions, such as rotations.
Roth Gerhard, Whitehead Anthony
doaj   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

open access: yesMolecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns   +10 more
wiley   +1 more source

Symbolic Algorithm for Solving Nonlocal Boundary Value Problems for Systems of Ordinary Integrodifferential Equations

open access: yesAlgorithms
Boundary value problems for systems of integrodifferential equations appear in many branches of science and engineering. Accuracy in modeling complex processes requires the specification of nonlocal boundary conditions, including multipoint and integral ...
Efthimios Providas   +2 more
doaj   +1 more source

Subtype‐specific enhancer RNAs define transcriptional regulators and prognosis in breast cancers

open access: yesMolecular Oncology, EarlyView.
This study employed machine learning methodologies to perform the subtype‐specific classification of RNA‐seq data sets, which are mapped on enhancers from TCGA‐derived breast cancer patients. Their integration with gene expression (referred to as ProxCReAM eRNAs) and chromatin accessibility profiles has the potential to identify lineage‐specific and ...
Aamena Y. Patel   +6 more
wiley   +1 more source

Censoring, Factorizations, and Spectral Analysis for Transition Matrices with Block-Repeating Entries [PDF]

open access: yes
In this paper, we use the Markov chain censoring technique to study infinite state Markov chains whose transition matrices possess block-repeating entries.
W. John Braun, Wei Li, Yiqiang Q. Zhao,
core  

Network divergence analysis identifies adaptive gene modules and two orthogonal vulnerability axes in pancreatic cancer

open access: yesMolecular Oncology, EarlyView.
Tumors contain diverse cellular states whose behavior is shaped by context‐dependent gene coordination. By comparing gene–gene relationships across biological contexts, we identify adaptive transcriptional modules that reorganize into distinct vulnerability axes.
Brian Nelson   +9 more
wiley   +1 more source

Epsilon-near-zero ITO/Ag/SiO2 metamaterial for large nonlinear absorption

open access: yesEPJ Applied Metamaterials
Enhanced nonlinear optical response contributes to higher device efficiency, lower power consumption and more compact integration. In this study, we designed an epsilon-near-zero multilayer metamaterial composed of Ag, ITO and SiO2.
Dong Jiannan   +6 more
doaj   +1 more source

Efficient image features selection and weighting for fundamental matrix estimation

open access: yesIET Computer Vision, 2016
In computer vision, it is a challenge to compute the relationship of multiple views from scene images. The view relationship can be obtained from the fundamental matrix.
Liqiang Wang, Zhen Liu, Zhonghua Zhang
doaj   +1 more source

Fundamental matrix of solutions for one class of parabolic degenerate systems

open access: yesKarpatsʹkì Matematičnì Publìkacìï, 2013
We consider one class of ultraparabolic equation systems of second order, that have three groups of degenerated variables and coefficients of which depend only on a time variable.
I. V. Burtnyak, H. P. Malytska
doaj   +1 more source

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