Results 91 to 100 of about 14,824 (273)

The First Photometric Analysis of Two Low-mass-ratio Contact Binary Systems in TESS Survey

The Astronomical Journal
Low-mass-ratio ( q ) contact binary systems are progenitors of stellar mergers such as blue stragglers or fast-rotating FK Com stars. In this study, we present the first light curve analysis of two newly identified low mass-ratio contact binary systems ...
Qiyuan Cheng, Jianping Xiong, Xu Ding, Kaifan Ji, Jiao Li, Chao Liu, Jiangdan Li, Jingxiao Luo, Xin Lyu, Zhanwen Han, Xuefei Chen   +10 more
doaj   +1 more source

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

Molecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser, Florian Krumbach, Eyleen Corrales, Geoffroy Andrieux, Christian Preisinger, Franziska Liss, Alexandra Golzmann, Melanie Boerries, Kerstin Becker, Ruth Knüchel, Stefan Garczyk, Bernhard Lüscher   +11 more
wiley   +1 more source

The Secondary Component of the Extremely Low Mass Ratio Massive Binary HD 165246 Revealed by GHOST

The Astrophysical Journal
In the pursuit of understanding the multiplicity of massive stars, the OWN Survey has undertaken spectroscopic monitoring of hundreds of targets over the past 20 yr.
C. N. Rodriguez, T. Ansin, G. A. Ferrero, O. G. Benvenuto, R. Gamen, N. I. Morrell, J. I. Arias, R. E. Higa, C. Putkuri, C. Johnston, K. Chiboucas, E. Deibert, C. R. Hayes, J.-E. Heo, M. Jeong, V. Kalari, E. Martioli, V. M. Placco, K. A. Venn, S. Xu, R. Diaz, M. Gomez-Jimenez, R. Ruiz-Carmona, C. Simpson, A. W. McConnachie, J. Pazder, G. Burley, T. A. M. Berg, J. G. Robertson, K. Labrie, J. Thomas-Osip   +30 more
doaj   +1 more source

Multi‐omic characterization of consensus molecular subtype 1 (CMS1) colorectal cancer with dampened immune response improves precision medicine

Molecular Oncology, EarlyView.
This study highlights the importance of multi‐omic analyses in characterizing colorectal cancers. Indeed, our analysis revealed a rare CMS1 exhibiting dampened immune activation, including reduced PD‐1 expression, moderate CD8+ T‐cell infiltration, and suppressed JAK/STAT pathway.
Livia Concetti, Manuel Scimeca, Julia Bischof, Jonathan Woodsmith, Massimiliano Agostini, Cristina Fiorani, Yufang Shi, Eleonora Candi, Gerry Melino, Alessandro Mauriello, Giuseppe S. Sica   +10 more
wiley   +1 more source

A Homogeneous Catalog of Oscillating Solar-type Stars Observed by the Kepler Mission and a New Amplitude Scaling Relation Including Chromospheric Activity

The Astronomical Journal
We present a homogeneous catalog of global asteroseismic parameters and derived stellar parameters for 765 Kepler main-sequence and subgiant stars. The catalog was produced by reanalyzing all available Kepler DR25 short-cadence data using pySYD , an ...
Maryum Sayeed, Daniel Huber, Ashley Chontos, Yaguang Li   +3 more
doaj   +1 more source

Fundamental parameters of Galactic luminous OB stars IV. The upper HR diagram [PDF]

, 1999
A. Herrero, J. Puls, M. R. Villamariz
openalex   +1 more source

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

Molecular Oncology, EarlyView.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani, Gilgi Friedlander, Gili Perry, Nora Balint‐Lahat, Shlomit Gilad, Dana Morzaev‐Sulzbach, Anjana Shenoy, Noa Bossel Ben‐Moshe, Anya Pavlovsky, Rinat Bernstein‐Molho, Eytan Domany, Iris Barshack, Tamar Geiger, Bella Kaufman, Einav Nili Gal‐Yam   +14 more
wiley   +1 more source

Absolute Calibration. IV. Use of G-type Stars as Primary Calibrators

The Astronomical Journal
We demonstrate an approach to determine spectral energy distribution (SED) templates that are accurate to the 1% level from the visible through the infrared for nearby (unextincted) solar-type stars. Our approach is based only on measurements of T _eff ,
G. H. Rieke, Everett Schlawin, Charles R. Proffitt, Christopher Willmer   +3 more
doaj   +1 more source

B stars in open clusters: fundamental parameters [PDF]

, 2010
Y. Aidelman, L. S. Cidale, J. Zorec, M. L. Arias   +3 more
openalex   +1 more source

Tonic signaling of the B‐cell antigen‐specific receptor is a common functional hallmark in chronic lymphocytic leukemia cell phosphoproteomes at early disease stages

Molecular Oncology, EarlyView.
B‐cell chronic lymphocytic leukemia (B‐CLL) and monoclonal B‐cell lymphocytosis (MBL) show altered proteomes and phosphoproteomes, analyzed using mass spectrometry, protein microarrays, and western blotting. Identifying 2970 proteins and 316 phosphoproteins, including 55 novel phosphopeptides, we reveal BCR and NF‐kβ/STAT3 signaling in disease ...
Paula Díez, Pablo Juanes‐Velasco, Marina L. García‐Vaquero, Conrad Droste, Alicia Landeira‐Viñuela, Miguel Alcoceba, Helena Fidalgo‐Gómez, Sara Misiego‐Herrero, Almudena Navarro‐Bailón, Mónica Baile, José M. Bastida, Jose Manuel Sanchez‐Santos, Rafael Góngora, Julia Almeida, Marcos Gonzalez‐Diaz, Alberto Orfao, Javier De Las Rivas, Manuel Fuentes   +17 more
wiley   +1 more source