Results 111 to 120 of about 207,560 (312)

The Fundamental Stellar Parameters of FGK Stars in the SEEDS Survey

, 2017
Large exoplanet surveys have successfully detected thousands of exoplanets to-date. Utilizing these detections and non-detections to constrain our understanding of the formation and evolution of planetary systems also requires a detailed understanding of
Abe, Lyu, Akiyama, Eiji, Brandner, Wolfgang, Brandt, Timothy D., Cargile, Phillip, Carson, Joseph C., Currie, Thayne M, Egner, Sebastian, Feldt, Markus, Fukagawa, Misato, Goto, Miwa, Grady, Carol A., Guyon, Olivier, Hashimoto, Jun, Hayano, Yutaka, Hayashi, Masahiko, Hayashi, Saeko S., Hebb, Leslie, Helminiak, Krzysztof G., Henning, Thomas, Hodapp, Klaus W., Ishii, Miki, Iye, Masanori, Janson, Markus, Kandori, Ryo, Knapp, Gillian R., Kudo, Tomoyuki, Kusakabe, Nobuhiko, Kuzuhara, Masayuki, Kwon, Jungmi, Matsuo, Taro, Mayama, Satoshi, McElwain, Michael W., Miyama, Shoken, Momose, Munetake, Morino, Jun-Ichi, Moro-Martin, Amaya, Nakagawa, Takao, Nishimura, Tetsuo, Oh, Daehyeon, Okamoto, Yoshiko K., Pyo, Tae-Soo, Rich, Evan A., Schlieder, Joshua, Serabyn, Eugene, Sitko, Michael L., Suenaga, Takuya, Suto, Hiroshi, Suzuki, Ryuji, Takahashi, Yasuhiro H., Takami, Hideki, Takami, Michihiro, Takato, Naruhisa, Tamura, Motohide, Terada, Hiroshi, Thalmann, Christian, Tomono, Daigo, Turner, Edwin L., Usuda, Tomonori, Watanabe, Makoto, Wisniewski, John P., Yamada, Toru   +61 more
core   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source

Calibration of LAMOST Stellar Surface Gravities Using the Kepler Asteroseismic Data

, 2016
Asteroseismology is a powerful tool to precisely determine the evolutionary status and fundamental properties of stars. With the unprecedented precision and nearly continuous photometric data acquired by the NASA Kepler mission, parameters of more than ...
Cao, Z., Hou, Y., Li, Y., Liu, C., Luo, A., Wang, L., Wang, W., Wang, Y., Wu, Y., Zhang, Y., Zhao, G.   +10 more
core   +1 more source

Energy Distributions and Fundamental Parameters of 6 A Stars [PDF]

International Astronomical Union Colloquium, 1993
AbstractThe energy distributions (EDs) of 6 peculiar (3 Aps and 3 λ Bootis) stars are presented from 1200Ȧ up to about 12000Ȧ. For those stars having infrared photometry, the integrated flux from 1200& to 22000Å has been calculated and the Infrared Flux Method (IRFM, Blackwell and Shallis, 1977) applied to derive effective temperatures and angular ...
openaire   +1 more source

Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma

Molecular Oncology, EarlyView.
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken, Andrea Abel Gutierrez, Imke van Rossum, Cornelia G. Spruijt, Michiel Vermeulen, Guido van Mierlo, Blanca Scheijen, Annemiek B. van Spriel   +7 more
wiley   +1 more source

Detailed Investigation of a W UMa Contact Binary with an Ultralow Mass Ratio and a Third Body as a Potential Merger Candidate

The Astrophysical Journal
The lower limit of the mass ratio in contact binaries remains uncertain, with observations suggesting systems exist below theoretical predictions. The stability of such very-low-mass-ratio systems is still debated.
Atila Poro, Ehsan Paki, Fahri Alicavus, Raul Michel   +3 more
doaj   +1 more source

PARP inhibition and pharmacological ascorbate demonstrate synergy in castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon, Peter T. Gallagher, Orly I. Richter, Neermala Poudel Neupane, Amy C. Mandigo, Jennifer J. McCann, Emanuela Dylgjeri, Irina Vasilevskaya, Christopher McNair, Channing J. Paller, Wm. Kevin Kelly, Karen E. Knudsen, Matthew J. Schiewer, Ayesha A. Shafi   +13 more
wiley   +1 more source

Low-mass Eclipsing Binaries KIC 4908495, KIC 6466939, and KIC 9474485: Isolated Pre-main-sequence Systems?

The Astrophysical Journal
We present a detailed analysis of three Kepler eclipsing binaries, KIC 4908495, KIC 6466939, and KIC 9474485. Our analysis reveals that these systems are composed of components possessing a lower mass than our Sun with slight subsolar metallicities ...
Orkun Özdarcan
doaj   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

Molecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix, Daniel Samaga, Katharina Gehr, Benedek Dankó, Mohamed Schumann, Guido Drexler, Ahmed Alnatsha, Georg Beyer, Ujjwal Mahajan, Martin Selmansberger, Julia Mayerle, Claus Belka, Horst Zitzelsberger, Kirsten Lauber   +13 more
wiley   +1 more source

Photometric and Spectroscopic Studies of Two Early-type Eclipsing Binaries

The Astrophysical Journal
Using high-precision photometric data from the Transiting Exoplanet Survey Satellite, medium-resolution spectroscopic data from the Large Sky Area Multi-Object Fiber Spectroscopy Telescope, and long-term eclipse timings, we provide orbital parameters for
Pengfei Ye, Kai Li, Fei Liu, Xiang Gao, Jing-Yi Wang   +4 more
doaj   +1 more source