Results 101 to 110 of about 166,438,504 (289)

Design and analysis strategies for robust microbiome ageing research

FEBS Letters, EarlyView.
The gut microbiome changes with age and associates with age‐related morbidity and mortality, establishing it as a potential biomarker and intervention target for ageing. Realising this potential requires methodological rigour, yet distinguishing biological signals from methodological artefacts remains challenging across cohorts. This review provides an
Mark Olenik, İsmail Güderer, Yi Wang, Tayyaba Alvi, Prasoon Pandey, Handan Melike Dönertaş   +5 more
wiley   +1 more source

Scaling K2. VIII. Short-period Sub-Neptune Occurrence Rates Peak Around Early-type M Dwarfs

The Astronomical Journal
We uniformly combined data from the NASA Kepler and K2 missions to compute planet occurrence rates across the entire FGK and M-dwarf stellar range. The K2 mission, driven by targets selected by guest observers, monitored nine times more M dwarfs than the
Kevin K. Hardegree-Ullman, Galen J. Bergsten, Jessie L. Christiansen, Jon K. Zink, Sakhee Bhure, Kiersten M. Boley, Rachel B. Fernandes, Steven Giacalone, Preethi R. Karpoor   +8 more
doaj   +1 more source

Decoding the dynamic extracellular matrix in cancer—3D models and bioscaffolds rewire the rules of tumor progression

FEBS Letters, EarlyView.
Cancer progression is regulated by the dynamic matrix code of the tumor microenvironment, which influences cellular behavior and disease development. Importantly, matrix remodeling in three‐dimensional cancer models more accurately reflects in vivo conditions compared to conventional two‐dimensional systems.
Sylvia Mangani, Konstantinos Spanopoulos, Zoi Piperigkou, Nikos K. Karamanos   +3 more
wiley   +1 more source

Fundamental effective temperature measurements for eclipsing binary stars – VII. The solar twin in LL Aquarii [PDF]

The eclipsing binary LL Aqr is a bright V=9.32, detached system consisting of two solar-type stars in an eccentric orbit (P = 20.2 d). The secondary component, LL Aqr B, was previously found to have physical and atmospheric parameters very similar to the
Maxted, Pierre, Graczyk, Dariusz, Miller, Nicola, Hahlin, Axel   +3 more
core   +1 more source

A Star-based Method for the Precise Flux Calibration of the Chinese Space Station Telescope Slitless Spectroscopic Survey

The Astrophysical Journal Supplement Series
The upcoming Chinese Space Station Telescope (CSST) slitless spectroscopic survey poses a challenge of flux calibration, which requires a large number of flux-standard stars.
Lin Yang, Haibo Yuan, Fuqing Duan, Ruoyi Zhang, Bowen Huang, Kai Xiao, Shuai Xu, Jinming Zhang   +7 more
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

FM stars II: a Fourier view of pulsating binary stars - determining binary orbital parameters photometrically for highly eccentric cases [PDF]

, 2015
Continuous and precise space-based photometry has made it possible to measure the orbital frequency modulation of pulsating stars in binary systems with extremely high precision over long time spans.
Kurtz, Donald W., Murphy, Simon J., Kurtz, Donald Wayne, Murphy, S. J., Shibahashi, Hiromoto, Shibahashi, H.   +5 more
core   +1 more source

Conserved binding mode but diverse interfaces of MreC‐PBP2 interactions

FEBS Letters, EarlyView.
The crystal structure of abMreC reveals a conserved two β‐barrel architecture and provides structural insights into its role within the bacterial elongasome. The abMreC–abPBP2 complex model identifies the molecular basis of MreC‐mediated PBP2 recognition, contributing to the regulation of peptidoglycan synthesis.
Hyunseok Jang, Hyo Been Jin, Chang Min Kim, So Yeon Lee, Hyun Ho Park   +4 more
wiley   +1 more source

The Properties of V1016 Orionis, the Eclipsing Binary in the Trapezium System θ1 Orionis A

The Astronomical Journal
We have obtained high-dispersion spectroscopy, Strömgren y photometry, and Bessel BV measurements of the eclipsing binary V1016 Ori, which is part of the triple system θ ^1  Ori A that is one of the four bright Trapezium stars.
James R. Sowell, Francis C. Fekel, Gregory W. Henry, Michael H. Williamson, James D. Armstrong, Ryan Aipa, Martino Stino   +6 more
doaj   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source