Results 121 to 130 of about 166,438,504 (289)

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

B stars in open clusters: fundamental parameters [PDF]

, 2011
We use the BCD spectrophotometric classification system to derive fundamental parameters of B stars in NGC 2439, NGC 3766 and NGC 6087. We are able to perform a complete study of each open cluster by deriving spectral classification of its members ...
Arias, María Laura, Zorec, Juan, Cidale, Lydia Sonia, Aidelman, Yael Judith   +3 more
core  

An Extremely Hot Pulsating Prewhite Dwarf from OGLE

The Astronomical Journal
We show that the blue 18.3 minutes variable object discovered in the Galactic disk by the OGLE-III survey and named OGLE-GD-WD-0001 is a pulsating prewhite dwarf of PG 1159 spectral type.
Paweł Pietrukowicz, Klaus Werner, Mateusz J. Mróz, Milena Ratajczak   +3 more
doaj   +1 more source

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Star formation across the galaxy : observations and modelling of the spectral energy distributions of young stars [PDF]

, 2009
In the last few decades, the emergence of large-scale infrared surveys has led to a revolution in the study of star formation. In particular, NASA’s Spitzer Space Telescope has recently carried out mid- and far-infrared observations of numerous star ...
Robitaille, Thomas P.
core   +2 more sources

The First Photometric Analysis of Two Low-mass-ratio Contact Binary Systems in TESS Survey

The Astronomical Journal
Low-mass-ratio ( q ) contact binary systems are progenitors of stellar mergers such as blue stragglers or fast-rotating FK Com stars. In this study, we present the first light curve analysis of two newly identified low mass-ratio contact binary systems ...
Qiyuan Cheng, Jianping Xiong, Xu Ding, Kaifan Ji, Jiao Li, Chao Liu, Jiangdan Li, Jingxiao Luo, Xin Lyu, Zhanwen Han, Xuefei Chen   +10 more
doaj   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source

Fundamental parameters of He-weak and He-strong stars [PDF]

, 2019
Context. He-weak and He-strong stars are chemically peculiar AB objects whose He lines are anomalously weak or strong for their MK spectral type. The determination of fundamental parameters for these stars is often more complex than for normal stars due ...
Arias, María Laura, Cruzado, Alicia, Frémat, Y., Zorec, J., Cidale, Lydia Sonia, Torres, Andrea Fabiana   +5 more
core  

The Secondary Component of the Extremely Low Mass Ratio Massive Binary HD 165246 Revealed by GHOST

The Astrophysical Journal
In the pursuit of understanding the multiplicity of massive stars, the OWN Survey has undertaken spectroscopic monitoring of hundreds of targets over the past 20 yr.
C. N. Rodriguez, T. Ansin, G. A. Ferrero, O. G. Benvenuto, R. Gamen, N. I. Morrell, J. I. Arias, R. E. Higa, C. Putkuri, C. Johnston, K. Chiboucas, E. Deibert, C. R. Hayes, J.-E. Heo, M. Jeong, V. Kalari, E. Martioli, V. M. Placco, K. A. Venn, S. Xu, R. Diaz, M. Gomez-Jimenez, R. Ruiz-Carmona, C. Simpson, A. W. McConnachie, J. Pazder, G. Burley, T. A. M. Berg, J. G. Robertson, K. Labrie, J. Thomas-Osip   +30 more
doaj   +1 more source

From junk to function — How weak selection in eukaryotes builds new parts and drives genomic complexity

FEBS Letters, EarlyView.
How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley   +1 more source