Results 141 to 150 of about 173,796,379 (301)

Preoperative circulating tumor cells integrated with imaging analysis for prognostic evaluation in head and neck squamous cell carcinoma

Molecular Oncology, EarlyView.
Detecting circulating tumor cells (CTCs) in blood before surgery may help predict outcomes in patients with head and neck squamous cell carcinoma (HNSCC). Here, we show when combined with tumor size and lymph node involvement from routine imaging, CTC status identifies high‐risk patients with poorer survival—offering a simple, minimally invasive tool ...
Susanne Flach, Gizem Abaci, Tom Huberty, Axel Lechner, Lukas Käsmann, Jens Ricke, Sophia Stöcklein, Martin Canis, Philipp Baumeister, Marianna Alunni‐Fabbroni   +9 more
wiley   +1 more source

Sliced Inverse Regression: application to fundamental stellar parameters

, 2019
We present a method for deriving the stellar fundamental parameters. It is based on a regularized sliced inverse regression (RSIR).We first tested it on noisy synthetic spectra of A, F, G, and K-type stars, and inverted simultaneously their atmospheric ...
Kassounian Sarkis, Paletou Frédéric, Gebran Marwan, Watson Victor   +3 more
core   +1 more source

A Test of FeH Line Parameters Using DR19 APOGEE Spectra of Benchmark M Dwarfs

The Astrophysical Journal
Recent studies have suggested a mismatch of up to 0.20 dex between iron abundances derived from Fe I and FeH lines in the H -band spectra of M dwarfs and in this work we investigate the nature of this possible offset.
Anderson Silva-Andrade, Diogo Souto, Katia Cunha, Verne V. Smith, Carlos Allende Prieto, Ricardo P. Schiavon, Verónica Loaiza-Tacuri, Aida Behmard, Dmitry Bizyaev, Ilija Medan, Dan Qiu, Bárbara Rojas-Ayala   +11 more
doaj   +1 more source

The Fundamental Stellar Parameters of FGK Stars in the SEEDS Survey

, 2017
Large exoplanet surveys have successfully detected thousands of exoplanets to-date. Utilizing these detections and non-detections to constrain our understanding of the formation and evolution of planetary systems also requires a detailed understanding of the basic properties of their host stars.
Rich, Evan A., Wisniewski, John P., McElwain, Michael W., Hashimoto, Jun, Kudo, Tomoyuki, Kusakabe, Nobuhiko, Okamoto, Yoshiko K., Abe, Lyu, Akiyama, Eiji, Brandner, Wolfgang, Brandt, Timothy D., Cargile, Phillip, Carson, Joseph C., Currie, Thayne M, Egner, Sebastian, Feldt, Markus, Fukagawa, Misato, Goto, Miwa, Grady, Carol A., Guyon, Olivier, Hayano, Yutaka, Hayashi, Masahiko, Hayashi, Saeko S., Hebb, Leslie, Helminiak, Krzysztof G., Henning, Thomas, Hodapp, Klaus W., Ishii, Miki, Iye, Masanori, Janson, Markus, Kandori, Ryo, Knapp, Gillian R., Kuzuhara, Masayuki, Kwon, Jungmi, Matsuo, Taro, Mayama, Satoshi, Miyama, Shoken, Momose, Munetake, Morino, Jun-Ichi, Moro-Martin, Amaya, Nakagawa, Takao, Nishimura, Tetsuo, Oh, Daehyeon, Pyo, Tae-Soo, Schlieder, Joshua, Serabyn, Eugene, Sitko, Michael L., Suenaga, Takuya, Suto, Hiroshi, Suzuki, Ryuji, Takahashi, Yasuhiro H., Takami, Michihiro, Takato, Naruhisa, Terada, Hiroshi, Thalmann, Christian, Tomono, Daigo, Turner, Edwin L., Watanabe, Makoto, Yamada, Toru, Takami, Hideki, Usuda, Tomonori, Tamura, Motohide   +61 more
openaire   +2 more sources

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

Physical parameters of three field RR Lyrae stars [PDF]

, 2013
This work was partially supported by DGAPA–Universidad Nacional Autonoma de Mexico through project IN104612.Stromgren uvby - beta photometry of the stars classified as RR Lyrae stars RU Piscium, SS Piscium and TU Ursae Majoris has been used to estimate ...
Jaimes, R. Figuera, Ferro, A. Arellano, Pena, J. H.   +2 more
core  

The Y Dwarf Companion to the White Dwarf WD 0806-66: Resolving the Discrepancy between Atmospheric and Evolutionary Models

The Astrophysical Journal
James Webb Space Telescope near- and mid-infrared spectroscopy has been published by M. Voyer et al. and B. W. P. Lew et al. for the Y dwarf, which is a distant companion to the white dwarf WD 0806-661.
S. K. Leggett, Pascal Tremblin
doaj   +1 more source

Partial FAK suppression promotes tumor growth, an effect reversed by macrophage p110δ PI3K inactivation

Molecular Oncology, EarlyView.
Partial inhibition of focal adhesion kinase (FAK) can paradoxically promote tumor growth, rather than simply producing a weaker antitumor effect than that observed with strong FAK suppression. In breast cancer and melanoma models, targeting p110δ PI3K, particularly in macrophages, counteracted these tumor‐promoting effects, highlighting the importance ...
Lydia Xenou, Niki Tzenaki, Anna Tsapara, Maria Tzardi, Evangelia A. Papakonstanti   +4 more
wiley   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

Fundamental Parameters Of The Lowest Mass Stars To The Highest Mass Planets

, 2016
The physical and atmospheric properties of ultracool dwarfs are deeply entangled due to the degenerate effects of mass, age, metallicity, clouds and dust, activity, rotation, and possibly even formation mechanism on observed spectra. Accurate determination of funda- mental parameters for a wide diversity of objects at the low end of the initial mass ...
openaire   +2 more sources