Results 161 to 170 of about 14,659 (294)

Analysing the significance of small conformational changes and low occupancy states in serial crystallographic data

FEBS Open Bio, EarlyView.
This protocol paper outlines methods to establish the success of a time‐resolved serial crystallographic experiment, by means of statistical analysis of timepoint data in reciprocal space and models in real space. We show how to amplify the signal from excited states to visualise structural changes in successful experiments.
Jake Hill, Yelyzaveta Pulnova, Elke De Zitter, Helen M. Ginn, Briony A. Yorke   +4 more
wiley   +1 more source

Photometric and Spectroscopic Investigations of Three Large Amplitude Contact Binaries

The Astronomical Journal
We performed photometric and spectroscopic studies of three large amplitude contact binaries: NSVS 2418361, ATLAS J057.1170+31.2384, and NSVS 7377875. The amplitudes of these three systems’ light curves are more than 0.7 mag. We analyzed the light curves
Xin Xu, Kai Li, Fei Liu, Qian-Xue Yan, Yi-Fan Wang, Xin-Yu Cui, Jing-Yi Wang, Xing Gao, Guo-You Sun, Cheng-Yu Wu, Mu-Zi-Mei Li   +10 more
doaj   +1 more source

Rapid screening of staphylokinase protein variants using an unpurified cell‐free expression system

FEBS Open Bio, EarlyView.
An unpurified cell‐free protein synthesis (CFPS) platform enables rapid functional screening of staphylokinase variants. Direct plasminogen‐activation assays performed in microplate format provide real‐time activity readouts, allowing rapid identification and ranking of variants with improved or reduced fibrinolytic activity without protein ...
Maria Tomková, Veronika Hovanová, Jiri Damborsky, Erik Sedlák   +3 more
wiley   +1 more source

High-resolution Spectroscopic Analysis of Four Unevolved Barium Stars

The Astronomical Journal
A classical local thermodynamic equilibrium analysis, based on high-resolution spectroscopic data, is performed for a sample of three potential barium dwarf candidates and one star already recognized as such.
M. P. Roriz, N. Holanda, L. V. da Conceição, S. Junqueira, N. A. Drake, A. Sonally, C. B. Pereira   +6 more
doaj   +1 more source

Systemic dysregulation of apolipoproteins in amyotrophic lateral sclerosis serum

FEBS Open Bio, EarlyView.
Amyotrophic lateral sclerosis (ALS) is a fatal disease that damages motor neurons. This study found that people with ALS show significant changes in blood fats and the proteins that carry them. Several apolipoproteins were higher, lipid balances were altered, and normal protein–lipid relationships were disrupted.
Finula I. Isik, Russell Pickford, Hannah C. Timmins, Olivier Piguet, Glenda M. Halliday, Matthew C. Kiernan, Woojin Scott Kim   +6 more
wiley   +1 more source

On the Maximum Mass and Oblateness of Rotating Neutron Stars with Generic Equations of State

The Astrophysical Journal
A considerable effort has been dedicated recently to the construction of generic equations of state (EOSs) for matter in neutron stars. The advantage of these approaches is that they can provide model-independent information on the interior structure and
Carlo Musolino, Christian Ecker, Luciano Rezzolla   +2 more
doaj   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Photometric Analysis of 30 Contact Binaries in M31

The Astrophysical Journal
M31, as the largest galaxy in the Local Group, is of significant importance for the study of stellar formation and evolution. Based on the data of 5859 targets observed in M31 by Gu et al., we selected 30 contact binaries by visual inspection for further
Xiang Gao, Kai Li, Li-Heng Wang, Hai-bo Yuan, Hong-rui Gu, Ya-Ni Guo   +5 more
doaj   +1 more source

The skills required for transition to university and study in biological sciences: A student perspective

FEBS Open Bio, EarlyView.
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley   +1 more source

BCD spectrophotometry of stars with the B[e] phenomenon : I. Fundamental Parameters [PDF]

, 2010
Low resolution spectra in the λλ3500-4600 Å wavelength range of 23 stars with the B[e] phenomenon are presented. Spectral classification of 15 program stars was performed using the BCD spectrophotometric system, based on the study of the Balmer ...
Tringaniello, María Luján Ramona, Zorec, Juan, Cidale, Lydia Sonia   +2 more
core