Results 161 to 170 of about 207,560 (312)

Fast Rotation vs. Metallicity

open access: yes, 2005
Fast rotation seems to be the major factor to trigger the Be phenomenon. Surface fast rotation can be favored by initial formation conditions such as metal abundance.
Fremat, Yves   +3 more
core   +1 more source

Differential expression of cancer‐related genes supports prediction of poor response to first‐line treatments in T‐ALL pediatric patients with high minimal residual disease

open access: yesMolecular Oncology, EarlyView.
In the present work, we have identified a transcriptional signature based on the differential expression of six genes (BCL2&MAST4, HSH2D&LAT2, METRN&PITPNM2) that would facilitate the early detection of T‐cell acute lymphoblastic leukemia (T‐ALL) patients prone to a poor treatment response and could be implemented at diagnosis, along with other risk ...
Antonio Lahera   +11 more
wiley   +1 more source

Search for and Analysis of Eclipsing Binaries in the LAMOST Medium-resolution Survey Field. I. R.A.: 23h01m51s, Decl.: +34°36′45″

open access: yesThe Astrophysical Journal
Eclipsing binaries (EBs) play an important astrophysical role in studying stellar properties and evolution. By analyzing photometric data in the the Large Sky Area Multi-Object Fiber Spectroscopic Telescope (LAMOST) Medium-Resolution Survey field, R.A ...
Jing-Yi Wang   +9 more
doaj   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

open access: yesMolecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu   +10 more
wiley   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

open access: yesMolecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Discoveries and Properties of EL CVn–type Binaries in the TESS Survey

open access: yesThe Astrophysical Journal
EL CVn–type systems represent a rare evolutionary stage in binary star evolution, providing ideal laboratories for investigating stable mass-transfer processes and the formation of extremely low-mass white dwarfs (ELM WDs).
Jianping Xiong   +7 more
doaj   +1 more source

NKCC1: A key regulator of glioblastoma progression

open access: yesMolecular Oncology, EarlyView.
Glioblastoma (GBM) progression is driven by disrupted chloride cotransporter homeostasis. NKCC1 is highly expressed in stem‐like, astrocytic, and progenitor cells, correlating with earlier recurrence, while overall survival remains unaffected. NKCC1 serves as a prognostic marker and potential therapeutic target, linking chloride transporter imbalance ...
Anja Thomsen   +5 more
wiley   +1 more source

Photometric and Spectroscopic Investigations of Three Large Amplitude Contact Binaries

open access: yesThe Astronomical Journal
We performed photometric and spectroscopic studies of three large amplitude contact binaries: NSVS 2418361, ATLAS J057.1170+31.2384, and NSVS 7377875. The amplitudes of these three systems’ light curves are more than 0.7 mag. We analyzed the light curves
Xin Xu   +10 more
doaj   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

open access: yesMolecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena   +15 more
wiley   +1 more source

High-resolution Spectroscopic Analysis of Four Unevolved Barium Stars

open access: yesThe Astronomical Journal
A classical local thermodynamic equilibrium analysis, based on high-resolution spectroscopic data, is performed for a sample of three potential barium dwarf candidates and one star already recognized as such.
M. P. Roriz   +6 more
doaj   +1 more source

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