Results 151 to 160 of about 173,796,379 (301)

Extracellular vesicle lipidomics liquid biopsy reveals systemic and tumor microenvironment metabolic reprogramming in ovarian cancer

Molecular Oncology, EarlyView.
Extracellular vesicle (EV) lipidomic profiling of plasma and ascites from patients with high‐grade serous ovarian cancer and of ovarian cancer cell lines reveals enrichment of triglycerides (TGs), diacylglycerols (DGs), phosphatidylcholine (PCs), sphingomyelins (SMs), reflecting tumor metabolic reprogramming.
Shikha Rani, Dominic Guanzon, Andrew Lai, Katherin Scholz‐Romero, Sarah Reed, Edita Ritmejeryte, Rohan Lourie, Naven Chetty, Kaltin Ferguson, Carlos Salomon   +9 more
wiley   +1 more source

Fundamental parameters of RR Lyrae stars from multicolour photometry and Kurucz atmospheric models - III. SW And, DH Peg, CU Com, DY Peg

, 2014
We report the most comprehensive UBV(RI)C observations of the bright, radially pulsating field stars SW And, DH Peg, CU Com, DY Peg. Long term variation has been found in the ultraviolet colour curves of SW And and DH Peg.
Barcza, Szabolcs, Benkő, József
core   +1 more source

Accurate and Model-independent Radius Determination of Single FGK and M Dwarfs Using Gaia DR3 Data

The Astronomical Journal
Measuring fundamental stellar parameters is key to fully comprehending the evolution of stars. However, current theoretical models overpredict effective temperatures, and underpredict radii, compared to observations of K and M dwarfs (radius inflation ...
Rocio Kiman, Timothy D. Brandt, Jacqueline K. Faherty, Mark Popinchalk   +3 more
doaj   +1 more source

Predictive and prognostic biomarkers of Bacillus Calmette‐Guérin therapy failure in bladder cancer patients: A systematic review

Molecular Oncology, EarlyView.
High‐risk bladder cancer is typically treated with Bacillus Calmette‐Guérin (BCG), but 30–40% of patients relapse. No FDA‐ or CE‐approved biomarkers currently predict or prognosticate BCG failure. We systematically reviewed the literature and identified 72 eligible studies, revealing several promising biomarkers associated with BCG treatment response ...
Rui Ribeiro‐Pereira, Ana Teixeira‐Marques, Rui Freitas, João A Carvalho, Sara Monteiro‐Reis, Giorgio I. Russo, Rui Henrique, Carmen Jerónimo   +7 more
wiley   +1 more source

Regulation of the lncRNA NEAT1 by p53‐ΔNp63 crosstalk modulates the DNA damage response and therapeutic efficacy in HNSCC

Molecular Oncology, EarlyView.
In head and neck squamous cell carcinoma (HNSCC) p53 and p63 exert opposite roles on the transcription regulation of the lncRNA NEAT1. Under basal conditions, p53 levels are low and p63 represses NEAT1 expression. Upon genotoxic stress, p53 is rapidly induced, displacing p63 from the NEAT1 promoter leading to NEAT1 transcriptional activation and ...
Sara De Domenico, Veronica La Banca, Silvia D'Amico, Stefano Scalera, Sara Nicolai, Angelo Peschiaroli   +5 more
wiley   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

Molecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez, Rafael Pérez‐Díaz, Hugo Ramos‐Solano, Marina Garrido‐Casado, Vanessa C. Talayero, Miguel Vicente‐Manzanares   +5 more
wiley   +1 more source

The determination of fundamental parameters of CP-stars by spectroscopic methods: comparison with interferometry data [PDF]

, 2018
В работе представлены результаты определения эффективных температур, ускорения свободного падения, химического состава, радиусов и светимостей двух СР-звезд (HD 188041 и HD 111133). Собраны параметры еще для восьми CP-звезд.
Shulyak, D. V., Романовская, А. М., Рябчикова, Т. А., Ryabchikova, T. A., Шуляк, Д. В., Romanovskaya, A. M.   +5 more
core  

Exploring NGC 7067: Comprehensive Analysis of Multiwavelength Photometric, Reddening, and Orbit Using Gaia DR3 and 2MASS

The Astrophysical Journal
This study used Bayesian analysis alongside various statistical methods to examine the young open cluster NGC 7067, utilizing Gaia DR3 and Two Micron All Sky Survey data.
Zihan Chen, Feng Wang, Huanbin Chi, Hui Deng, Ying Mei   +4 more
doaj   +1 more source

p190A/ARHGAP35 and p190B/ARHGAP5 proteins in endometrial cancer: a novel cancer‐relevant paralog interplay

Molecular Oncology, EarlyView.
This study identifies ARHGAP5, in addition to the frequently mutated ARHGAP35, as significantly mutated in endometrial cancer. Mutations in both genes co‐occur and are associated with their correlated downregulation. Functional CRISPR studies show that both paralogs regulate similar pathways, including actin cytoskeleton organization.
Mathilde Pinault, Capucine Heraud, Mélissa Correia de Oliveira, Véronique Neaud, Valérie Valesco, Valérie Prouzet‐Mauleon, Béatrice Turcq, Jean‐William Dupuy, Anne‐Aurélie Raymond, Sabrina Croce, Frédéric Saltel, Valérie Lagrée, Violaine Moreau   +12 more
wiley   +1 more source

BSN. II. The First Light Curve Study of Eight Total Eclipsing Contact Binary Stars with Shallow Fillout Factors

The Astronomical Journal
This study provides the first comprehensive analysis of eight total-eclipse W Ursae Majoris-type contact binary systems. Ground-based photometric multiband observations were conducted at a Mexican observatory, and new times of minima were extracted.
Atila Poro, Kai Li, Raul Michel, Li-Heng Wang, Fahri Alicavus, Morgan Rhai Nájera, Priscila Santillán-Ortega, Francisco Javier Tamayo, Hector Aceves   +8 more
doaj   +1 more source