Results 21 to 30 of about 6,035,009 (269)

On the evolution of fungal and yeast cell walls [PDF]

Yeast, 2010
AbstractRecent developments in genomics and proteomics provide evidence that yeast and other fungal cell walls share a common origin. The fibrous component of yeast cell walls usually consists of β‐glucan and/or chitin. N‐glycosylated proteins form an amorphous, cross‐linking matrix as well as fibres on the outer surfaces of the walls.
Xianfa, Xie, Peter N, Lipke
openaire   +2 more sources

Characterization of Extracellular Vesicles Produced by Aspergillus fumigatus Protoplasts

mSphere, 2020
Extracellular vesicles (EVs) are membranous compartments produced by yeast and mycelial forms of several fungal species. One of the difficulties in perceiving the role of EVs during the fungal life, and particularly in cell wall biogenesis, is caused by ...
Juliana Rizzo, Thibault Chaze, Kildare Miranda, Robert W. Roberson, Olivier Gorgette, Leonardo Nimrichter, Mariette Matondo, Jean-Paul Latgé, Anne Beauvais, Marcio L. Rodrigues   +9 more
doaj   +3 more sources

The Aspergillus fumigatus Phosphoproteome Reveals Roles of High-Osmolarity Glycerol Mitogen-Activated Protein Kinases in Promoting Cell Wall Damage and Caspofungin Tolerance

mBio, 2020
The filamentous fungus Aspergillus fumigatus can cause a distinct set of clinical disorders in humans. Invasive aspergillosis (IA) is the most common life-threatening fungal disease of immunocompromised humans. The mitogen-activated protein kinase (MAPK)
Eliciane Cevolani Mattos, Lilian Pereira Silva, Clara Valero, Patrícia Alves de Castro, Thaila Fernanda dos Reis, Liliane F. C. Ribeiro, Mark R. Marten, Rafael Silva-Rocha, Cauã Westmann, Carlos Henrique Tomich de Paula da Silva, Carlton Anthony Taft, Narjes Al-Furaiji, Michael Bromley, Uffe H. Mortensen, J. Philipp Benz, Neil Andrew Brown, Gustavo H. Goldman   +16 more
doaj   +1 more source

What Are the Functions of Chitin Deacetylases in Aspergillus fumigatus?

Frontiers in Cellular and Infection Microbiology, 2020
Deacetylation of chitin by chitin deacetylases (Cda) results in the formation of chitosan. Chitosan, a polymer of β1,4 linked glucosamine, plays multiple roles in the function of the fungal cell wall, including virulence and evasion of host immune ...
Isabelle Mouyna, Sarah Dellière, Anne Beauvais, Fabrice Gravelat, Fabrice Gravelat, Brendan Snarr, Brendan Snarr, Mélanie Lehoux, Caitlin Zacharias, Caitlin Zacharias, Yan Sun, Steven de Jesus Carrion, Eric Pearlman, Donald C. Sheppard, Donald C. Sheppard, Jean-Paul Latgé   +15 more
doaj   +1 more source

The role of the cell wall in fungal pathogenesis [PDF]

Microbial Biotechnology, 2009
Summary Fungal infections are a serious health problem. In recent years, basic research is focusing on the identification of fungal virulence factors as promising targets for the development of novel antifungals. The wall, as the most external cellular component, plays a crucial role in the interaction with host cells mediating ...
Arana, David M., Prieto, Daniel, Román, Elvira, Nombela, César, Alonso‐Monge, Rebeca, Pla, Jesús   +5 more
openaire   +2 more sources

Constitutive expression of a grapevine polygalacturonase-inhibiting protein affects gene expression and cell wall properties in uninfected tobacco [PDF]

, 2011
Background Polygalacturonase-inhibiting proteins (PGIPs) directly limit the effective ingress of fungal pathogens by inhibiting cell wall-degrading endopolygalacturonases (ePGs).
Dan Jacobson, Becker, John V. W., Katherine J Denby, Vivier Melané A, Eric Nguema-Ona, Becker John VW, Steyn Cobus, Alexandersson, Erik, Vivier, Melané A., Nguema-Ona Eric, Vivier, Melane, John VW Becker, Denby Katherine J, Cobus Steyn, Denby, Katherine J., Denby, Katherine, Becker, John, Steyn, Cobus, Melané A Vivier, Jacobson, Dan, Nguema-Ona, Eric, Alexandersson Erik, Jacobson Dan, Erik Alexandersson   +23 more
core   +1 more source

Host carbon sources modulate cell wall architecture, drug resistance and virulence in a fungal pathogen [PDF]

, 2012
Open Access via PMCID: PMC3465787Peer ...
Brand, Alexandra C., Gow, Neil A. R., Wehmeier, Silvia, Ene, Iuliana Veronica, Gow, Neil Andrew Robert, Brown, Alistair James Petersen, Adya, Ashok, MacCallum, Donna M., Brown, Alistair J. P., Brand, Alex, Adya, Ashok K., MacCallum, Donna Margaret, Ene, Iuliana V.   +12 more
core   +1 more source

Protein Kinase A and High-Osmolarity Glycerol Response Pathways Cooperatively Control Cell Wall Carbohydrate Mobilization in Aspergillus fumigatus

mBio, 2018
Aspergillus fumigatus mitogen-activated protein kinases (MAPKs) are involved in maintaining the normal morphology of the cell wall and providing resistance against cell wall-damaging agents.
Leandro José de Assis, Adriana Manfiolli, Eliciane Mattos, João H. T. Marilhano Fabri, Iran Malavazi, Ilse D. Jacobsen, Matthias Brock, Robert A. Cramer, Arsa Thammahong, Daisuke Hagiwara, Laure Nicolas Annick Ries, Gustavo Henrique Goldman   +11 more
doaj   +1 more source

Phylogenomic Analyses of Nucleotide-Sugar Biosynthetic and Interconverting Enzymes Illuminate Cell Wall Composition in Fungi

mBio, 2021
This study provides new insights into the complex evolutionary history of the fungal cell wall. We analyzed fungal enzymes that convert sugars acquired from the environment into the diverse sugars that make up the fundamental building blocks of the cell ...
Julian Schwerdt, Hao Qiu, Neil Shirley, Alan Little, Vincent Bulone   +4 more
doaj   +1 more source

Diversity of Cell Wall Related Proteins in Human Pathogenic Fungi

Journal of Fungi, 2017
The cell wall is one of the major keys to fungal identity. Fungi use their cell wall to sense the environment, and localize nutrients and competing microorganism. Pathogenic species additionally modify their cell walls to hide from a host’s immune system.
Anna Muszewska, Sebastian Piłsyk, Urszula Perlińska-Lenart, Joanna S. Kruszewska   +3 more
doaj   +1 more source