Results 41 to 50 of about 208,417 (290)

Hsp90 orchestrates transcriptional regulation by Hsf1 and cell wall remodelling by MAPK signalling during thermal adaptation in a pathogenic yeast [PDF]

, 2012
Acknowledgments We thank Rebecca Shapiro for creating CaLC1819, CaLC1855 and CaLC1875, Gillian Milne for help with EM, Aaron Mitchell for generously providing the transposon insertion mutant library, Jesus Pla for generously providing the hog1 hst7 ...
A Ali, A Mitchell, A Plaine, A Roetzer, A Roetzer, A Walther, A Winkler, AA Duina, AE Piispanen, Alex Andrianopoulos, Alistair J. P. Brown, AP Gasch, B Eisman, B Enjalbert, B Enjalbert, B Enjalbert, BK Jakobsen, C Csank, C Giardina, C Queitsch, C San Jose, CA Munro, Carol Munro, CH de Dios, CJ Nobile, D Chen, DA Davis, DA Smith, DF Jarosz, DF Jarosz, DF Smith, DM Arana, DR Wysong, E Kussell, E Leberer, E Nikolaou, E Roman, EA Craig, EA Elion, ET Burt, F Estruch, F Lamoth, F Navarro-Garcia, F Navarro-Garcia, F Navarro-García, F Sherman, FA Guhad, G Degols, G Wiederrecht, G Wiederrecht, GJ Gallo, H Garreau, H Lavoie, HC Causton, I Tirosh, IV Ene, J Chen, J Zou, JL Brewster, JR Blankenship, K-H Chen, LA Walker, LA Walker, LE Cowen, Leah E. Cowen, Louise Walker, M Ramsdale, M Taipale, MD Leach, MD Leach, MD Leach, MD Leach, ME Feder, Michelle D. Leach, MM Bradford, N Shulga, P Gónzalez-Párraga, P Hawle, PD Cantero, PK Sorger, PK Sorger, R Alonso-Monge, R Alonso-Monge, R Diez-Orejas, RA Monge, RB Wilson, RS Hegde, RS Shapiro, S Bates, S Diezmann, S Kuge, S Nicholls, S Nicholls, S Nicholls, SD Singh, SH Millson, SK Prill, SL LaFayette, SL Rutherford, SM Noble, SM O'Rourke, SM Roe, Susan Budge, TT Wimalasena, VM Bruno, VM Bruno, WA Fonzi, WM Toone, X Zhang, Y Guo, Y Kamada   +110 more
core   +3 more sources

Glycosylation of Candida albicans cell wall proteins is critical for induction of innate immune responses and apoptosis of epithelial cells.

PLoS ONE, 2012
C. albicans is one of the most common fungal pathogen of humans, causing local and superficial mucosal infections in immunocompromised individuals. Given that the key structure mediating host-C.
Jeanette Wagener, Günther Weindl, Piet W J de Groot, Albert D de Boer, Susanne Kaesler, Selvam Thavaraj, Oliver Bader, Daniela Mailänder-Sanchez, Claudia Borelli, Michael Weig, Tilo Biedermann, Julian R Naglik, Hans Christian Korting, Martin Schaller   +13 more
doaj   +1 more source

Quantitative Analysis of Candida Cell Wall Components by Flow Cytometrywith Triple-Fluorescence Staining [PDF]

, 2017
This work was supported by the European Commission within the FP7 Framework Programme [Fungitect-Grant No 602125]. We also thank Thomas Sauer, Vienna Biocenter Campus (VBC), Austria, for technical support at the FACS facility of the MFPL, Karl Kuchler ...
Gow, N, Istel, F, Jenull, S, Lion, T, Nogueira, MF, Walker, L A   +5 more
core   +1 more source

Exploiting fungal cell wall components in vaccines [PDF]

Seminars in Immunopathology, 2014
Innate recognition of fungi leads to strong adaptive immunity. Investigators are trying to exploit this observation in vaccine development by combining antigens with evolutionarily conserved fungal cell wall carbohydrates to induce protective responses.
Stuart M, Levitz, Haibin, Huang, Gary R, Ostroff, Charles A, Specht   +3 more
openaire   +2 more sources

The Aspergillus fumigatus cell wall integrity signalling pathway: drug target, compensatory pathways and virulence

Frontiers in Microbiology, 2015
Aspergillus fumigatus is the most important airborne fungal pathogen, causing severe infections with invasive growth in immunocompromised patients. The fungal cell wall prevents the cell from lysing and protects the fungus against environmental stress ...
Vito eValiante, Juliane eMacheleidt, Martin eFöge, Axel A Brakhage   +3 more
doaj   +1 more source

Lactate signalling regulates fungal β-glucan masking and immune evasion [PDF]

, 2016
AJPB: This work was supported by the European Research Council (STRIFE, ERC- 2009-AdG-249793), The UK Medical Research Council (MR/M026663/1), the UK Biotechnology and Biological Research Council (BB/K017365/1), the Wellcome Trust (080088; 097377).
A Hopke, B Ferwerda, BN Gantner, C Kuei, CA Johnston, CA Munro, CA Rappleye, CJ Barelle, CJ Heilmann, DH Owen, DO Inglis, E Leberer, FN Gravelat, G Bindea, GD Brown, GJ Sosinska, HJ Flint, I Jacobs, ID Iliev, IV Ene, IV Ene, IV Ene, IV Ene, JE Nett, JM Bain, K Lemaire, LE Lewis, LM Graham, M Galán-Díez, M Karababa, M Santos, MG Netea, MG Netea, MJ Marakalala, MM Maidan, MT Kelly, N Vieira, NAR Gow, P Shannon, PR Desai, RA Hall, RT Wheeler, RT Wheeler, RT Wheeler, S Lev, S Shahana, SdJ Carrion, SE Hardison, SM Noble, TR O'Meara, YL Chen   +50 more
core   +1 more source

Vesicular transport across the fungal cell wall [PDF]

Trends in Microbiology, 2009
Recent findings indicate that fungi use vesicular transport to deliver substances across their cell walls. Fungal vesicles are similar to mammalian exosomes and could originate from cytoplasmic multivesicular bodies. Vesicular transport enables the export of large molecules across the cell wall, and vesicles contain lipids, proteins and polysaccharides,
Arturo, Casadevall, Joshua D, Nosanchuk, Peter, Williamson, Marcio L, Rodrigues   +3 more
openaire   +2 more sources

The Transcription Factor SomA Synchronously Regulates Biofilm Formation and Cell Wall Homeostasis in Aspergillus fumigatus

mBio, 2020
Polysaccharides are key components of both the fungal cell wall and biofilm matrix. Despite having distinct assembly and regulation pathways, matrix exopolysaccharide and cell wall polysaccharides share common substrates and intermediates in their ...
Yuan Chen, Francois Le Mauff, Yan Wang, Ruiyang Lu, Donald C. Sheppard, Ling Lu, Shizhu Zhang   +6 more
doaj   +1 more source

Nanoscale glucan polymer network causes pathogen resistance. [PDF]

, 2014
Successful defence of plants against colonisation by fungal pathogens depends on the ability to prevent initial penetration of the plant cell wall. Here we report that the pathogen-induced (1,3)-β-glucan cell wall polymer callose, which is deposited at ...
A deBary, AK Jacobs, B Huang, B Schwessinger, D Ellinger, E Betzig, H Saito, J Ries, JD Jones, JE Carles, JL Him, L Mangin, M Heilemann, M Stein, MA Hubbe, MJ Rust, MT Nishimura, N Juge, NA Evans, S Sato, SPS Chundawat, T Harada, VN Belov, Z Zhao   +23 more
core   +1 more source

The basic leucine zipper transcription factor MeaB is critical for biofilm formation, cell wall integrity, and virulence in Aspergillus fumigatus

mSphere
The regulation of fungal cell wall biosynthesis is crucial for cell wall integrity maintenance and directly impacts fungal pathogen virulence. Although numerous genes are involved in fungal cell wall polysaccharide biosynthesis through multiple pathways,
Yuan Chen, Fei Gao, Xiaojin Chen, Siyuan Tao, Peiying Chen, Wei Lin   +5 more
doaj   +1 more source