Results 31 to 40 of about 6,035,009 (269)

An Ssd1 Homolog Impacts Trehalose and Chitin Biosynthesis and Contributes to Virulence in Aspergillus fumigatus

open access: yesmSphere, 2019
Regulation of fungal cell wall biosynthesis is critical to maintain cell wall integrity in dynamic fungal infection microenvironments. Genes involved in this response that impact fungal fitness and host immune responses remain to be fully defined.
Arsa Thammahong   +4 more
doaj   +1 more source

Insect fungal pathogens secrete a cell wall-associated glucanase that acts to help avoid recognition by the host immune system.

open access: yesPLoS Pathogens, 2023
Fungal insect pathogens have evolved diverse mechanisms to evade host immune recognition and defense responses. However, identification of fungal factors involved in host immune evasion during cuticular penetration and subsequent hemocoel colonization ...
Huifang Wang   +8 more
doaj   +1 more source

Autolytic Enzymes in Fungal Cell Walls [PDF]

open access: yesJournal of General Microbiology, 1966
SUMMARY: Autolytic glucanase and protease activity was detected in cell walls of some pythium species prepared by ultrasonic treatment. The glucanase activity was correlated with mycelial development. Maximal glucose release was detected in growing cultures during the linear growth period of the fungus.
R, Mitchell, N, Sabar
openaire   +2 more sources

Scalar nanostructure of the Candida albicans cell wall; a molecular, cellular and ultrastructural analysis and interpretation

open access: yesThe Cell Surface, 2020
Despite the importance of fungal cell walls as the principle determinant of fungal morphology and the defining element determining fungal interactions with other cells, few scalar models have been developed that reconcile chemical and microscopic ...
Megan D. Lenardon   +4 more
doaj   +1 more source

Immunotherapy of invasive fungal infection in hematopoietic stem cell transplant recipients [PDF]

open access: yes, 2013
Despite the availability of new antifungal compounds, invasive fungal infection remains a significant cause of morbidity and mortality in children and adults undergoing allogeneic hematopoietic stem cell transplantation (HSCT). Allogeneic HSCT recipients
Lehrnbecher, Thomas   +7 more
core   +1 more source

Replicative Aging Remodels the Cell Wall and Is Associated with Increased Intracellular Trafficking in Human Pathogenic Yeasts

open access: yesmBio, 2022
Replicative aging is an underexplored field of research in medical mycology. Cryptococcus neoformans (Cn) and Candida glabrata (Cg) are dreaded fungal pathogens that cause fatal invasive infections.
Vanessa K. A. Silva   +6 more
doaj   +1 more source

Structure of Fungal Cell Wall Polysaccharides

open access: yesNippon Ishinkin Gakkai Zasshi, 2006
Candida albicans mannan consists of the alpha-1,6-linked backbone moiety and the alpha-1,2- and alpha-1,3-linked side chains. It also contains alpha-1,6-branched mannose units, beta-1,2-linked mannose units, and phosphate groups. The cell wall mannans of the genus Candida possess three types of beta-1,2 linked mannose units.
Shibata, Nobuyuki, Okawa, Yoshio
openaire   +3 more sources

The Aspergillus fumigatus cell wall integrity signalling pathway: drug target, compensatory pathways and virulence

open access: yesFrontiers in Microbiology, 2015
Aspergillus fumigatus is the most important airborne fungal pathogen, causing severe infections with invasive growth in immunocompromised patients. The fungal cell wall prevents the cell from lysing and protects the fungus against environmental stress ...
Vito eValiante   +3 more
doaj   +1 more source

Fungal chitin induces trained immunity in human monocytes during cross-talk with Saccharomyces cerevisiae [PDF]

open access: yes, 2015
Objectives: Candida albicans, a common colonizer of the human mucosa, is able to train innate immune cells in a process mediated by the β-glucans present in the cell wall1.
Lenucci, M. S.   +10 more
core   +1 more source

Neutrophil Attack Triggers Extracellular Trap-Dependent Candida Cell Wall Remodeling and Altered Immune Recognition.

open access: yesPLoS Pathogens, 2016
Pathogens hide immunogenic epitopes from the host to evade immunity, persist and cause infection. The opportunistic human fungal pathogen Candida albicans, which can cause fatal disease in immunocompromised patient populations, offers a good example as ...
Alex Hopke   +5 more
doaj   +1 more source

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