Results 91 to 100 of about 13,270 (230)

Metabolic Dysfunction‐Associated Steatotic Liver Disease and Obesity: Pathogenesis, Diagnostics, Risk Stratification, and Therapeutic Approach

The Kaohsiung Journal of Medical Sciences, EarlyView.
ABSTRACT Metabolic dysfunction‐associated steatotic liver disease (MASLD) has emerged as the most prevalent chronic liver disease worldwide, closely linked to the global rising incidence of obesity and metabolic syndrome. This review synthesizes current evidence on the pathogenesis, gut–liver axis, and multidisciplinary management of MASLD within the ...
Beom Kyung Kim
wiley   +1 more source

Salivary mycobiome dysbiosis and its potential impact on bacteriome shifts and host immunity in oral lichen planus [PDF]

, 2019
The biodiversity of the mycobiome, an important component of the oral microbial community, and the roles of fungal–bacterial and fungal–immune system interactions in the pathogenesis of oral lichen planus (OLP) remain largely uncharacterized.
Lu, Changqing, Changqing Lu, Kun Wang, Jizhong Zhou, Yao, Yufei, Xiao, Liying, Zhou, Jizhong, Xin Shen, Yufei Yao, Li, Yan, Zhang, Bo, Wenyuan Shi, He, Jinzhi, Van Nostrand, Joy D, Qichao Tu, Shen, Xin, Biao Ren, Yan Li, Ren, Biao, Xuedong Zhou, Cui, Bomiao, Shi, Wenyuan, Tu, Qichao, Liying Xiao, Zhou, Xuedong, Wang, Kun, Joy D. Van Nostrand, Bomiao Cui, Bo Zhang, Jinzhi He   +29 more
core   +1 more source

Coccidioidomycosis and Host Microbiome Interactions: What We Know and What We Can Infer from Other Respiratory Infections

, 2023
Between 70 and 80% of Valley fever patients receive one or more rounds of antibiotic treatment prior to accurate diagnosis with coccidioidomycosis. Antibiotic treatment and infection (bacterial, viral, fungal, parasitic) often have negative implications ...
Susana Tejeda-Garibay, Katrina K. Hoyer
core   +1 more source

The Role of Polyphenols in Respiratory and Gut Health: From the Perspective of Gut‐Lung Axis

Phytotherapy Research, EarlyView.
ABSTRACT The gut‐lung axis constitutes a dynamic, multidirectional communication platform between the gastrointestinal and respiratory tracts. Its complexity arises from the integrated crosstalk among the microbiota, immune system, and redox homeostasis, collectively influencing disease susceptibility and progression.
Jian Kang, YongJun Du, Yanmei Hou, Liangliang Hao, Zhen Chen, Haoyang Xie, Chuantao Zhang, Lei Li   +7 more
wiley   +1 more source

The signatures and crosstalk of gut mycobiome, microbiome, and metabolites in drug-induced liver injury

Mycology
Drug-induced liver injury (DILI) is a significant adverse drug reaction with a rising incidence, yet it lacks specific non-invasive biomarkers for diagnosis and severity stratification.
Weiyan Huang, Yirui Hu, Zexuan Li, Jiake Che, Shuyan Wang, Ye Yang, Shengqi Yan, Yue Chen, Wenkang Gao, Fuyu Yang, Ting Wei, Kai Liu, Yuanqing Zhu, Yupin Tan, Yue Yang, Xinyang Wang, Yonggang Yuan, Zhuang Cao, Xiaotong Du, Jiahao Liu, Ling Yang, Huikuan Chu   +21 more
doaj   +1 more source

Human Colitis‐on‐Chip Model Reveals Dual Roles of Butyrate in Epithelial and Macrophage Defense Against Candida albicans Tissue Invasion

Small, EarlyView.
This study establishes a human immunocompetent colitis‐on‐chip model that mimics inflamed gut mucosa and enables quantitative analysis of Candida albicans tissue invasion under DSS‐induced injury. It reveals that microbiota‐derived butyrate simultaneously stabilizes epithelial junctions and reprograms macrophages via HDAC/NLRP3‐dependent mechanisms ...
Manuel Allwang, Maximilian Wipplinger, Parastoo Akbarimoghaddam, Raquel Alonso‐Roman, Zoltan Cseresnyes, Axel Dietschmann, Valentin Wegner, Adrian Feile, Yann Bachelot, Maria Warschinke, Mohamed I. Abdelwahab Hassan, Sonnhild Mittag, Otmar Huber, Bernhard Hube, Mark S. Gresnigt, Marc Thilo Figge, Alexander S. Mosig   +16 more
wiley   +1 more source

Modeling the lung‒brain axis in critical illness: Multifactorial crosstalk through organoids and organ‐on‐a‐chip system

VIEW, EarlyView.
Patients in intensive care units often experience lung injuries, complicated by brain problems. Advanced laboratory tools, organoids, and organs‐on‐chips facilitated the study of multiorgan interactions, help us understand the communication between the lungs and brain.
Wanyi Zhang, Ting Wang, Mengying Yao, Longxiang Su, Lixin Xie, Pan Pan   +5 more
wiley   +1 more source

Editorial: Women in fungal pathogenesis 2021

Frontiers in Cellular and Infection Microbiology, 2022
Angie Gelli, Clarissa J. Nobile, Clarissa J. Nobile, Eva Pericolini, Melanie Wellington   +4 more
doaj   +1 more source

Table_4_Gut mycobiome dysbiosis contributes to the development of hypertension and its response to immunoglobulin light chains.doc

, 2022
ObjectivesHuman gut microbiome has gained great attention for its proposed roles in the development of hypertension. The fungal microbiome in the human gut (i.e.
Anxing Ge (14309216), Brako Lydia (13693989), Yeqing Zou (9608496), Chen Huang (202847), Yanbo Yu (515669), Qianying Wang (6714641)   +5 more
core   +1 more source

Inflammatory Shift in Chronic Rhinosinusitis Amidst Guangzhou's Urbanization (2000–2018)

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Background Chronic rhinosinusitis (CRS) exhibits temporal and geographic diversity in pathological endotypes with progressive eosinophilic infiltration, while the underlying causes remain unclear. Current pathological endotypes determination relies on mean cell count per high‐power field, requiring accuracy optimization.
Ning Kang, Man‐Hou Chao, Xin Luo, Feng‐Wen Shan, Zi‐Xuan Hua, Ze‐Zhi Guo, Hua‐Mei Yan, He Zhang, Tong Wu, Min Zhou, Rui Zheng, Shuo Wu, Xue‐Kun Huang, Zhao‐Hui Shi, Ya‐Na Zhang, Ji Yang, Qin‐Tai Yang   +16 more
wiley   +1 more source