Results 51 to 60 of about 45,580 (175)

Deletion of both Dectin-1 and Dectin-2 affects the bacterial but not fungal gut microbiota and susceptibility to colitis in mice

Microbiome, 2022
Background Innate immunity genes have been reported to affect susceptibility to inflammatory bowel diseases (IBDs) and colitis in mice. Dectin-1, a receptor for fungal cell wall β-glucans, has been clearly implicated in gut microbiota modulation and ...
Yazhou Wang, Madeleine Spatz, Gregory Da Costa, Chloé Michaudel, Alexia Lapiere, Camille Danne, Allison Agus, Marie-Laure Michel, Mihai G. Netea, Philippe Langella, Harry Sokol, Mathias L. Richard   +11 more
doaj   +1 more source

Altered Gut Microbiota in Patients With Peutz–Jeghers Syndrome

Frontiers in Microbiology, 2022
BackgroundPeutz–Jeghers syndrome (PJS) is a rare genetic disorder characterized by the development of pigmented spots and gastrointestinal polyps and increased susceptibility to cancers.
Sui Wang, Sui Wang, Gang Huang, Gang Huang, Jue-Xin Wang, Jue-Xin Wang, Lin Tian, Lin Tian, Xiu-Li Zuo, Xiu-Li Zuo, Yan-Qing Li, Yan-Qing Li, Yan-Bo Yu, Yan-Bo Yu   +13 more
doaj   +1 more source

Understanding Human Microbiota Offers Novel and Promising Therapeutic Options against Candida Infections

, 2021
Human fungal pathogens particularly of Candida species are one of the major causes of hospital acquired infections in immunocompromised patients. The limited arsenal of antifungal drugs to treat Candida infections with concomitant evolution of multidrug ...
Zeeshan Fatima, Saif Hameed, Sandeep Hans, Shankar Thangamani, Ross Monasky   +4 more
core   +1 more source

Oral Myco- and Bacteriobiota and Yeast Infections in Mechanically Ventilated COVID-19 Patients

Microorganisms, 2023
Critically ill COVID-19 patients requiring mechanical ventilation in the intensive care unit are at risk of developing invasive candidiasis. In this study we aimed to (1) characterize oral cultivable mycobiota of mechanically ventilated adult COVID-19 ...
Iwona Gregorczyk-Maga, Michal Kania, Beata Sulik-Tyszka, Magdalena Namysł, Anna Sepioło, Dorota Romaniszyn, Estera Jachowicz-Matczak, Jadwiga Wójkowska-Mach   +7 more
doaj   +1 more source

Preterm gut microbiota and metabolome following discharge from intensive care

, 2015
The development of the preterm gut microbiome is important for immediate and longer-term health following birth. We aimed to determine if modifications to the preterm gut on the neonatal intensive care unit (NICU) impacted the gut microbiota and ...
Skeath, Tom, Perry, J. D. (John), Nelson, Andrew, Stewart, Christopher, Marrs, Emma, Embleton, Nicholas, Fernstad, Sara J., Fernstad, Sara Johansson, Berrington, Janet, Marrs, E. C. L. (Emma), Cummings, Stephen, Perry, John, Skeath, Thomas   +12 more
core   +1 more source

Neglected mycobiome in HIV infection: Alterations, common fungal diseases and antifungal immunity

Frontiers in Immunology, 2022
Human immunodeficiency virus (HIV) infection might have effects on both the human bacteriome and mycobiome. Although many studies have focused on alteration of the bacteriome in HIV infection, only a handful of studies have also characterized the ...
Shuang Li, Shuang Li, Xiaodong Yang, Xiaodong Yang, Christiane Moog, Christiane Moog, Hao Wu, Hao Wu, Bin Su, Bin Su, Tong Zhang, Tong Zhang   +11 more
doaj   +1 more source

Gut Fungal Microbiota Alterations in Pulmonary Arterial Hypertensive Rats. [PDF]

Biomedicines
The gut microbiome’s imbalance has been implicated in the pathogenesis of pulmonary arterial hypertension (PAH), yet the contribution of the gut mycobiome remains largely unclear. This study delineates the gut mycobiome profile in PAH and examines its interplay with the bacterial microbiome alterations. Fecal samples from monocrotaline-induced PAH rats
Chen Y, Meng L, Yuan W, Gao Z, Zhang X, Xie B, Song J, Li J, Zhong J, Liu X.   +9 more
europepmc   +4 more sources

Associations between fungal and bacterial microbiota of airways and asthma endotypes [PDF]

Journal of Allergy and Clinical Immunology, 2019
The relationship between asthma, atopy, and underlying type 2 (T2) airway inflammation is complex. Although the bacterial airway microbiota is known to differ in asthmatic patients, the fungal and bacterial markers that discriminate T2-high (eosinophilic) and T2-low (neutrophilic/mixed-inflammation) asthma and atopy are still incompletely identified ...
Anukriti, Sharma, Bharathi, Laxman, Edward T, Naureckas, D Kyle, Hogarth, Anne I, Sperling, Julian, Solway, Carole, Ober, Jack A, Gilbert, Steven R, White   +8 more
openaire   +2 more sources

Long-term alterations in gut microbiota following mild COVID-19 recovery: bacterial and fungal community shifts

Frontiers in Cellular and Infection Microbiology
ObjectiveCOVID-19 has had a profound impact on public health globally. However, most studies have focused on patients with long COVID or those in the acute phase of infection, with limited research on the health of individuals who have recovered from ...
Da Li, Da-Ya Zhang, Shi-Ju Chen, Yan-Ting Lv, Shi-Mei Huang, Chen Chen, Fan Zeng, Run-Xiang Chen, Xiao-Dong Zhang, Jian-Xin Xiong, Fa-Di Chen, Yue-Hong Jiang, Zhai Chen, Cui-Yi Mo, Jia-Jia Chen, Xu-Li Zhu, Li-Jun Zhang, Fei-Hu Bai, Fei-Hu Bai   +18 more
doaj   +1 more source

Gut Mycobiota Dysbiosis in Pulmonary Tuberculosis Patients Undergoing Anti-Tuberculosis Treatment

Microbiology Spectrum, 2021
Patients with pulmonary tuberculosis (TB) undergoing anti-tuberculosis (anti-TB) treatment were previously reported to present gut bacterial microbiota dysbiosis, but the role of the mycobiota has not been reported.
Demin Cao, Weihua Liu, Na Lyu, Boxing Li, Weibo Song, Yanxiao Yang, Jianliang Zhu, Zhiguo Zhang, Baoli Zhu   +8 more
doaj   +1 more source