Results 41 to 50 of about 495,774 (309)

Potential therapeutic targeting of BKCa channels in glioblastoma treatment

Molecular Oncology, EarlyView.
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak, Karolina Pytlak, Sandra Jaworowska, Bogusz Kulawiak, Piotr Bednarczyk   +4 more
wiley   +1 more source

Breeding of High-Polysaccharide-Producing Volvariella volvacea Strains Based on Genome Shuffling Technology

Journal of Fungi
Volvariella volvacea, a fungal species of Volvariella within the Pluteaceae family, is predominantly cultivated in southern China. Polysaccharides, the primary bioactive constituents of V. volvacea, exhibit diverse pharmacological activities.
Lihui Liang, Qihang Su, Yawei Wang, Peichen Du, Suzhen Zhao, Huanjie Zhang, Xiaofeng Gao   +6 more
doaj   +1 more source

Key Parameter Comparisons of Fungal Induced Mortality in Alfalfa Weevil Larvae (Coleoptera: Curculionidae) [PDF]

, 2017
Key parameters of alfalfa weevil larval mortality by Entornophthora phytonorni were compared weekly in three alfalfa fields.
Armbrust, Edward J, Barney, Robert J
core   +3 more sources

Comparative Effectiveness and Safety of Inebilizumab Versus Rituximab in AQP4‐IgG‐Positive NMOSD

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Rituximab (anti‐CD20, RTX) and inebilizumab (anti‐CD19, INE) represent B‐cell‐depleting therapies used for aquaporin‐4 antibody‐positive (AQP4‐IgG+) neuromyelitis optica spectrum disorder (NMOSD); however, direct comparative evidence remains limited.
Jie Lin, Binbin Xue, Dewei Xie, Jia Li, Juyuan Pan, Lanbing Zhu, Qiaowen Tong, Jing Lin, Ruofan Zhu, Xu Zhang, Junhui Xia, Xiang Li   +11 more
wiley   +1 more source

Core microbes in Cordyceps militaris sclerotia and their nitrogen metabolism-related ecological functions

Microbiology Spectrum
Cordyceps militaris infects insects and forms sclerotia within the insect remains, establishing insect–microbe complexes. Here, C. militaris sclerotia samples from a single location in China over a 5-year period were subjected to high-throughput DNA ...
Li Luo, Fei Dai, Zhongshun Xu, Jingqiang Guan, Gangxiang Fei, Jiaojiao Qu, Min Yao, Yuan Xue, Yeming Zhou, Xiao Zou   +9 more
doaj   +1 more source

Ionic Liquid-Based Ultrasonic-Assisted Extraction to Analyze Seven Compounds in Psoralea Fructus Coupled with HPLC

Molecules, 2019
Psoralea Fructus is widely used in traditional Chinese medicine (TCM), and the content of psoralen, isopsoralen, neobavaisoflavone, bavachin, psoralidin, isobavachalcone, and bavachinin A is the main quality control index of Psoralea Fructus because of ...
Mengjun Shi, Juanjuan Zhang, Cunyu Liu, Yiping Cui, Changqin Li, Zhenhua Liu, Wenyi Kang   +6 more
doaj   +1 more source

CAR T‐Cell Therapy in Neurology: A Scoping Review of Neuro‐Oncology, Autoimmune Diseases & Neurotoxicity

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Chimeric antigen receptor (CAR) T‐cell therapy has been investigated in neurological diseases, encompassing both central nervous system malignancies and autoimmune disorders, thereby extending its application beyond hematological cancers.
Omar Alqaisi, Mohammed Dibas, Patricia Tai, Ala Dibas, Osama Souied, Suhair Al‐Ghabeesh   +5 more
wiley   +1 more source

Antibacterial Mechanism of Dihydrotanshinone I

Natural Product Communications, 2021
The antimicrobial activity and the underlying action mechanisms of dihydrotanshinone I against Staphylococcus aureus , methicillin-resistant Staphylococcus aureus , extended-spectrum beta-lactamases Staphylococcus aureus were investigated with Kleihauer ...
Lin Zhao, Yingying Zhao, Jinfeng Wei, Zhenhua Liu, Changqin Li, Wenyi Kang   +5 more
doaj   +1 more source

Research progress on the polysaccharide extraction and antibacterial activity

Annals of Microbiology
Background Over time, the amount of germs resistant to antibacterial medications has been steadily rising because of their prolonged and indiscriminate use. The increase in drug resistance significantly threatens to human health and has become a globally
Lihui Liang, Qihang Su, Yu Ma, Shuzhen Zhao, Huanjie Zhang, Xiaofeng Gao   +5 more
doaj   +1 more source

Harnessing Fungal Biowelding for Constructing Mycelium‐Engineered Materials

Advanced Engineering Materials, EarlyView.
Mycelium‐bound composites (MBCs) offer low‐carbon alternatives for construction, yet interfacial bonding remains a critical challenge. This review examines fungal biowelding as a biocompatible adhesive, elucidating mycelium‐mediated interfacial mechanisms and their role in material assembly. Strategies to optimize biowelding are discussed, highlighting
Xue Brenda Bai, Xinrui Sarah Niu, Zhao Qin   +2 more
wiley   +1 more source