Results 91 to 100 of about 5,169 (249)

Arabidopsis glucosinolates trigger a contrasting transcriptomic response in a generalist and a specialist herbivore. [PDF]

open access: yes, 2017
Phytophagous insects have to deal with toxic defense compounds from their host plants. Although it is known that insects have evolved genes and mechanisms to detoxify plant allochemicals, how specialist and generalist precisely respond to specific ...
Heidel-Fischer, H.   +3 more
core   +1 more source

Bidirectional Regulation of NLRP3 Inflammasome and Mitochondrial Quality Control in Sepsis: Mechanisms and Therapeutic Implications

open access: yesMediators of Inflammation, Volume 2026, Issue 1, 2026.
Characterized by its capacity to induce organ failure, sepsis constitutes a life‐threatening pathological state with high incidence and mortality rates. Current treatments primarily focus on antimicrobial therapy and organ support, lacking direct interventions targeting the restoration of cellular or organelle function.
Xiangxin Liao   +5 more
wiley   +1 more source

CYP98A22, a phenolic ester 3’-hydroxylase specialized in the synthesis of chlorogenic acid, as a new tool for enhancing the furanocoumarin concentration in Ruta graveolens

open access: yesBMC Plant Biology, 2012
Background Furanocoumarins are molecules with proven therapeutic properties and are produced in only a small number of medicinal plant species such as Ruta graveolens.
Karamat Fazeelat   +7 more
doaj   +1 more source

Interações frutas/vegetais: fármaco com importância clínica [PDF]

open access: yes, 2014
Trabalho Complementar apresentado à Universidade Fernando Pessoa como parte dos requisitos para obtenção do grau de licenciada em Ciências da NutriçãoIntrodução: A ação profilática das frutas e vegetais em inúmeras doenças crónicas, como diabetes ...
Tavares, Cíntia Dalila Covêlo Sequeira
core  

Structures of Heracleum sosnovskii Manden. stem and leaves releasing photodermatosis-causing substances

open access: yesActa Agrobotanica, 2012
In its stems and leaves, Heracleum sosnovskii Manden. contains furanocoumarins, which exert a phototoxic effect on humans. The aim of the investigations was to describe the external secretory structures of the epidermis and internal secretory tissues in ...
Elżbieta Weryszko-Chmielewska   +1 more
doaj   +1 more source

Furanocoumarin compounds isolated from Dorstenia foetida potentiate irinotecan anticancer activity against colorectal cancer cells

open access: yesActa Pharmaceutica
Although the anticancer activity of Dorstenia foetida was already observed, the chemical entity responsible for this activity remained unidentified. In this study, the cytotoxic activity of two furanocoumarin compounds, i.e., 5-methoxy--3-(3-methyl-2,3 ...
Pengnam Supusson   +5 more
doaj   +1 more source

Plants with potential use on obesity and its complications [PDF]

open access: yes, 2015
Obesity is the most prevalent nutritional disease and a growing public health problem worldwide. This disease is a causal component of the metabolic syndrome related with abnormalities, including hyperglycemia, dyslipidemia, hypertension, inflammation ...
Gallegos-Infante, J. Alberto   +5 more
core   +1 more source

Phytochemicals from Ruta graveolens Activate TAS2R Bitter Taste Receptors and TRP Channels Involved in Gustation and Nociception

open access: yesMolecules, 2015
Ruta graveolens (rue) is a spontaneous plant in the Mediterranean area with a strong aroma and a very intense bitter taste, used in gastronomy and in folk medicine.
Giuseppe Mancuso   +3 more
doaj   +1 more source

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