Results 121 to 130 of about 2,292 (169)

Stereoselective Triplet‐Sensitised Radical Reactions of Furanone Derivatives

Chemistry – A European Journal, 2010
AbstractThe stereo‐ and regioselectivity of triplet‐sensitised radical reactions of furanone derivatives have been investigated. Furanones 7 a,b were excited to the 3ππ* state by triplet energy transfer from acetone. Intramolecular hydrogen abstraction then occurred such that hydrogen was transferred from the tetrahydropyran to the β position of the ...
Jahjah, Rabih, Gassama, Abdoulaye, Bulach, Véronique, Suzuki, Chikako, Abe, Manabu, Hoffmann, Norbert, Martinez, Agathe, Nuzillard, Jean‐marc   +7 more
openaire   +4 more sources

Synthesis of New Furanone Derivatives with Potent Anticancer Activity

Russian Journal of Bioorganic Chemistry, 2020
New compounds based on Furanone derivatives were synthesized by reaction of 3-(4-nitrobezylidine)-5-phenylfuran-2(3H)-one with various reagents as malononitrile then D-glucose, thiosemicarbazide then D-glucose, ethyl acetoacetate, acetyl acetone, ethyl cyanoacetate, hydrazine hydrate/acetic acid, thiourea, o-phenylene diamine, hydrazine hydrate/ethanol
W. H. Lashin, I. F. Nassar, A. F. El Farargy, A. O. Abdelhamid   +3 more
openaire   +1 more source

2(5H)-Furanone Derivatives as Inhibitors of Staphylococcal Biofilms

BioNanoScience, 2016
© 2016, Springer Science+Business Media New York.The opportunistic bacteria Staphylococcus aureus and Staphylococcus epidermidis often form rigid biofilms on wounds and artificial surfaces and thereby become extremely resistant to antimicrobials.
Elena Trizna, Liliya Latypova, Almira Kurbangalieva, Mikhail I. Bogachev, Airat Kayumov   +4 more
openaire   +3 more sources

Baoshanmycin and a New Furanone Derivative from a Soil‐Derived Actinomycete, Amycolatopsis sp. YNNP 00208

Chemistry & Biodiversity, 2022
AbstractActinomycetes have being regarded as a treasure reservoir of various bioactive secondary metabolites and devoted many antibiotics in clinicals. Amycolatopsis sp. YNNP 00208 was isolated from a soil sample collected in Gaoligong Mountain area, Yunnan Province, China.
Meng-An, Qian, Ya-Bin, Yang, Bin-Yuan, Hu, Yuan, Xu, Zi-Hang, Wang, Qin-Yuan, Li, Yu-Hong, Gao, Xiao-Dong, Luo, Li-Xing, Zhao   +8 more
openaire   +2 more sources

Diverse Pharmacological Potential of Various Furanone Derivatives: A Mini-Review

Mini-Reviews in Organic Chemistry, 2020
Abstract:: Furanone is present in many natural compounds. Furanone derivatives are playing important roles in pharmaceutical medicinal and organic chemistry. Various furanone derivatives were exhibited their different pharmacological activities such as antimicrobial, anti-inflammatory, anticancer, antiviral, antioxidant, and other anticipated ...
Asif Husain, Afzal Hussain, Wael A. Mahdi, Mohammad Asif   +3 more
openaire   +1 more source

Development of Fimbrolides, Halogenated Furanones and their Derivatives as Antimicrobial Agents

2015
Traditional treatment for bacterial infection is based on compounds that target bacterial viability or growth. However, a major concern with this approach is the frequent development of drug-resistant mutants. The discovery of bacterial quorum sensing (QS) systems, which control fundamental processes involved in bacterial physiology and virulence, has ...
Kitty K. K. Ho, Samuel K. Kutty, Daniel Chan, Renxun Chen, Mark D. P. Willcox, Naresh Kumar   +5 more
openaire   +1 more source

A New Furanone Isolated from a Marine-Derived Actinomycete M159

Chemistry of Natural Compounds, 2015
A new furanone, 5-(4',6'-dihydroxy-6'-methyloctyl)furan-2(5H)-one (1), and a known furanone, 5-(6',7'-dihydroxy-6'-methyloctyl)furan-2(5H)-one (2), were isolated from a marine-derived actinomycete (strain No. M159). The structures of these two compounds were determined on the basis of spectroscopic and chemical data.
Shuju Guo, Hua Su, Xiancui Li, Dayong Shi, Xiaobin Zhu   +4 more
openaire   +1 more source

Transformations of 3-(methylene)dihydro-2(3H)-furanone derivatives

Collection of Czechoslovak Chemical Communications, 1984
(E) and (Z)-3-(4-toluenesulfonyloxymethylene)dihydro-2(3H)-furanones ((E)-I) and ((Z-I) react with piperidine, pyrrolidine, morpholine, butanethiol, 4-toluenethiol, and 2-naphthalenethiol to give (E)-isomers of the corresponding enamines II-IV and thiomethylene derivatives V-VII in high yields. As has been shown, the reactions proceed with retention of
Ctibor Mazal, Zdeněk Jurka, Jaroslav Jonas   +2 more
openaire   +1 more source

A new synthesis of 5-methylene-2(5H)-furanone derivatives

Tetrahedron, 1984
Abstract 5-methylene-2(5H)-furanone derivatives are easily obtained by treatment of tertiary 2-furylcarbinols with pyridinium dichromate in dimethylformamide solution. Through this procedure, a natural product, the thiophene lactone isolated from Chamaemelum Nobile L., has been synthesized.
Antonioletti R, D'Auria M, De Mico A, Piancatelli G, Scettri A   +4 more
openaire   +2 more sources

[Antifungal activity of 5-benzilidene pyrrolone and furanone derivatives].

Annales pharmaceutiques francaises, 1991
The antifungal activity against Neurospora crassa of some 5-benzilidene pyrrolone and furanone derivatives was realised. Relations between the structure and this biological activity are established with Fujita-Ban and Hansch methods. The preponderant part of lipophilicity, resonance effect and E or Z configurations have been showed.
M G, de Carvalho, I da R, Pitta, S L, Galdino, G de C, Takaki, G, Bergé   +4 more
openaire   +1 more source