Results 131 to 140 of about 2,292 (169)
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Antifungal 3,5-disubstituted furanones: From 5-acyloxymethyl to 5-alkylidene derivatives
Bioorganic & Medicinal Chemistry, 20105-Acetoxymethyl-3-(4-bromophenyl)-2,5-dihydrofuran-2-one previously described as highly antifungally active was found to provide the corresponding 5-methylene derivative via an unusual DMSO-promoted elimination of the ester group at C5 under antifungal assay conditions.
Petr, Senel +8 more
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The Journal of Physical Chemistry B, 2006
Several 2'-substituted-2'-deoxyribonucleotides are potent inactivators of the enzyme ribonucleotide reductase (RNR), by destroying the essential tyrosyl radical located in subunit R2 or/and covalently alkylating the subunit R1. In the absence of external reductants, the inactivation is achieved by alkylation of subunit R1 by a methylene-3(2H)-furanone.
Nuno M F S A, Cerqueira +2 more
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Several 2'-substituted-2'-deoxyribonucleotides are potent inactivators of the enzyme ribonucleotide reductase (RNR), by destroying the essential tyrosyl radical located in subunit R2 or/and covalently alkylating the subunit R1. In the absence of external reductants, the inactivation is achieved by alkylation of subunit R1 by a methylene-3(2H)-furanone.
Nuno M F S A, Cerqueira +2 more
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Antibacterial effects and genotoxicity of new derivatives of furanones
2012New chlorine-containing furanones were tested for the presence of antibacterial activity and also for genotoxicity in Ames test. It has been established that the tested compounds had antibacterial properties. Antibacterial activities of all four compounds differed in rich broth and minimal glucose media.
Babynin E. +3 more
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Mechanism of electrochemical reduction of 5-thio derivatives of 2(5H)-furanone
Russian Chemical Bulletin, 2019© 2019, Springer Science+Business Media, Inc. The anionoid elimination of the substituent from position 5 of the lactone ring is the predominant pathway of electrochemical reduction of 5-arylsulfanyl- and 5-arylsulfonyl-3,4-dichloro-2(5H)-furanones in acetonitrile.
Latypova L. +3 more
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ChemInform Abstract: A New Synthetic Method for 2(5H)‐Furanone Derivatives.
Chemischer Informationsdienst, 1976AbstractDas Dianion des Thioäthers (I) reagiert mit den Epoxiden (II) zu den 2‐Furanon‐3‐thioäthern (III), deren Sulfoxide (IV) bei der Pyrolyse die 5‐substituierten 2(5H)‐Furanone (V) geben.
K. IWAI +4 more
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Antistaphylococcal activity of 2(5H)-furanone derivatives
2020Airat R. Kayumov +3 more
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New Method for Syntheses of Furanone Derivatives Using Dianions
HETEROCYCLES, 1984Kazuhiko Tanaka +3 more
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Novel and efficient synthesis of 2(5H)-furanone derivatives
The Journal of Organic Chemistry, 1988Yoo Tanabe, Nobuo Ohno
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FURANONE DERIVATIVES AND PRODUCTION METHOD THEREOF
2022YAMAGATA TAKUYA +5 more
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A New Synthetic Method for 2(5H)-Furanone Derivatives
HETEROCYCLES, 1975Kiyoshi Iwai +4 more
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