Results 151 to 160 of about 2,598 (200)

Stereoselective Triplet‐Sensitised Radical Reactions of Furanone Derivatives

open access: yesChemistry – A European Journal, 2010
AbstractThe stereo‐ and regioselectivity of triplet‐sensitised radical reactions of furanone derivatives have been investigated. Furanones 7 a,b were excited to the 3ππ* state by triplet energy transfer from acetone. Intramolecular hydrogen abstraction then occurred such that hydrogen was transferred from the tetrahydropyran to the β position of the ...
Jahjah, Rabih   +7 more
openaire   +4 more sources

Two furanone glucoside derivatives from Juniperus phœnicea

Phytochemistry, 1996
Abstract The rare compound, psydrin (5-methyl-4-O-(β- d -glucopyranosyl)-3(2H)-furanone) and the new 5-methyl-4-O-(β- d -glucopyranosyl)-3(2-isopropylidenyl)-furanone have been isolated from an acetone extract of the aerial parts of Juniperus phœnicea . Structural elucidation of the new product was achieved mainly by spectroscopic methods.
Gilles Comte   +2 more
exaly   +2 more sources

Discovery of novel furanone derivatives as potent Cdc7 kinase inhibitors

European Journal of Medicinal Chemistry, 2017
Cdc7 is a serine-threonine kinase and plays a conserved and important role in DNA replication, and it has been recognized as a potential anticancer target. Herein, we report the design, synthesis and structure-activity relationship of novel furanone derivatives as Cdc7 kinase inhibitors.
Takayuki Irie   +2 more
exaly   +3 more sources

2(5H)-Furanone Derivatives as Inhibitors of Staphylococcal Biofilms [PDF]

open access: yesBioNanoScience, 2016
© 2016, Springer Science+Business Media New York.The opportunistic bacteria Staphylococcus aureus and Staphylococcus epidermidis often form rigid biofilms on wounds and artificial surfaces and thereby become extremely resistant to antimicrobials.
Elena Trizna   +4 more
openaire   +4 more sources

γ -Butenolide and furanone derivatives from the soil-derived fungus Aspergillus sclerotiorum PSU-RSPG178

Phytochemistry, 2017
Chromatographic separation of the broth extract of the soil-derived fungus Aspergillus sclerotiorum PSU-RSPG178 resulted in isolation of four γ-butenolide-furanone dimers, aspersclerotiorones A-D, a furanone derivative, aspersclerotiorone E, and two γ-butenolide derivatives, aspersclerotiorones F and G, together with six known compounds, penicillic ...
Vatcharin Rukachaisirikul   +2 more
exaly   +3 more sources

Mechanism of electrochemical reduction of 5-thio derivatives of 2(5H)-furanone

open access: yesRussian Chemical Bulletin, 2019
© 2019, Springer Science+Business Media, Inc. The anionoid elimination of the substituent from position 5 of the lactone ring is the predominant pathway of electrochemical reduction of 5-arylsulfanyl- and 5-arylsulfonyl-3,4-dichloro-2(5H)-furanones in acetonitrile.
Latypova L.   +3 more
openaire   +3 more sources

Transformations of 3-(methylene)dihydro-2(3H)-furanone derivatives

open access: yesCollection of Czechoslovak Chemical Communications, 1984
(E) and (Z)-3-(4-toluenesulfonyloxymethylene)dihydro-2(3H)-furanones ((E)-I) and ((Z-I) react with piperidine, pyrrolidine, morpholine, butanethiol, 4-toluenethiol, and 2-naphthalenethiol to give (E)-isomers of the corresponding enamines II-IV and thiomethylene derivatives V-VII in high yields. As has been shown, the reactions proceed with retention of
Ctibor Mazal   +2 more
openaire   +2 more sources

Anti-Cryptococcal activity of a furanone derivative–antibiofilm and opsonophagocytic potential

Journal de Mycologie Médicale, 2020
Cryptococcus neoformans, an encapsulated fungal pathogen is evolving as a major threat to immune-compromised patients and rarely to healthy individuals also. The cell wall bound capsular polysaccharide, melanin pigment and biofilm formation are major virulence factors that are known to contribute to cryptococcal meningitis.
S S, Rathore   +5 more
openaire   +2 more sources

Furanone derivatives as quorum-sensing antagonists of Pseudomonas aeruginosa

Applied Microbiology and Biotechnology, 2008
The biofilm formation of Pseudomonas aeruginosa, an opportunistic human pathogen, is developed by cell-to-cell signaling, so-called quorum sensing (QS). To control the biofilm formation, we designed and synthesized new QS inhibitors of P. aeruginosa based on the structure of the previously known QS inhibitor, furanone.
Cheoljin, Kim   +6 more
openaire   +2 more sources

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