Results 151 to 160 of about 2,598 (200)
Stereoselective Triplet‐Sensitised Radical Reactions of Furanone Derivatives
AbstractThe stereo‐ and regioselectivity of triplet‐sensitised radical reactions of furanone derivatives have been investigated. Furanones 7 a,b were excited to the 3ππ* state by triplet energy transfer from acetone. Intramolecular hydrogen abstraction then occurred such that hydrogen was transferred from the tetrahydropyran to the β position of the ...
Jahjah, Rabih +7 more
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Two furanone glucoside derivatives from Juniperus phœnicea
Phytochemistry, 1996Abstract The rare compound, psydrin (5-methyl-4-O-(β- d -glucopyranosyl)-3(2H)-furanone) and the new 5-methyl-4-O-(β- d -glucopyranosyl)-3(2-isopropylidenyl)-furanone have been isolated from an acetone extract of the aerial parts of Juniperus phœnicea . Structural elucidation of the new product was achieved mainly by spectroscopic methods.
Gilles Comte +2 more
exaly +2 more sources
Discovery of novel furanone derivatives as potent Cdc7 kinase inhibitors
European Journal of Medicinal Chemistry, 2017Cdc7 is a serine-threonine kinase and plays a conserved and important role in DNA replication, and it has been recognized as a potential anticancer target. Herein, we report the design, synthesis and structure-activity relationship of novel furanone derivatives as Cdc7 kinase inhibitors.
Takayuki Irie +2 more
exaly +3 more sources
2(5H)-Furanone Derivatives as Inhibitors of Staphylococcal Biofilms [PDF]
© 2016, Springer Science+Business Media New York.The opportunistic bacteria Staphylococcus aureus and Staphylococcus epidermidis often form rigid biofilms on wounds and artificial surfaces and thereby become extremely resistant to antimicrobials.
Elena Trizna +4 more
openaire +4 more sources
Phytochemistry, 2017
Chromatographic separation of the broth extract of the soil-derived fungus Aspergillus sclerotiorum PSU-RSPG178 resulted in isolation of four γ-butenolide-furanone dimers, aspersclerotiorones A-D, a furanone derivative, aspersclerotiorone E, and two γ-butenolide derivatives, aspersclerotiorones F and G, together with six known compounds, penicillic ...
Vatcharin Rukachaisirikul +2 more
exaly +3 more sources
Chromatographic separation of the broth extract of the soil-derived fungus Aspergillus sclerotiorum PSU-RSPG178 resulted in isolation of four γ-butenolide-furanone dimers, aspersclerotiorones A-D, a furanone derivative, aspersclerotiorone E, and two γ-butenolide derivatives, aspersclerotiorones F and G, together with six known compounds, penicillic ...
Vatcharin Rukachaisirikul +2 more
exaly +3 more sources
Mechanism of electrochemical reduction of 5-thio derivatives of 2(5H)-furanone
© 2019, Springer Science+Business Media, Inc. The anionoid elimination of the substituent from position 5 of the lactone ring is the predominant pathway of electrochemical reduction of 5-arylsulfanyl- and 5-arylsulfonyl-3,4-dichloro-2(5H)-furanones in acetonitrile.
Latypova L. +3 more
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Transformations of 3-(methylene)dihydro-2(3H)-furanone derivatives
(E) and (Z)-3-(4-toluenesulfonyloxymethylene)dihydro-2(3H)-furanones ((E)-I) and ((Z-I) react with piperidine, pyrrolidine, morpholine, butanethiol, 4-toluenethiol, and 2-naphthalenethiol to give (E)-isomers of the corresponding enamines II-IV and thiomethylene derivatives V-VII in high yields. As has been shown, the reactions proceed with retention of
Ctibor Mazal +2 more
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Anti-Cryptococcal activity of a furanone derivative–antibiofilm and opsonophagocytic potential
Journal de Mycologie Médicale, 2020Cryptococcus neoformans, an encapsulated fungal pathogen is evolving as a major threat to immune-compromised patients and rarely to healthy individuals also. The cell wall bound capsular polysaccharide, melanin pigment and biofilm formation are major virulence factors that are known to contribute to cryptococcal meningitis.
S S, Rathore +5 more
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Furanone derivatives as quorum-sensing antagonists of Pseudomonas aeruginosa
Applied Microbiology and Biotechnology, 2008The biofilm formation of Pseudomonas aeruginosa, an opportunistic human pathogen, is developed by cell-to-cell signaling, so-called quorum sensing (QS). To control the biofilm formation, we designed and synthesized new QS inhibitors of P. aeruginosa based on the structure of the previously known QS inhibitor, furanone.
Cheoljin, Kim +6 more
openaire +2 more sources

