Results 61 to 70 of about 22,917 (286)

Computational and Data‐Driven Strategies for Lignocellulosic Biomass Valorization: From Multiscale Modeling to Digitalized Biorefinery Design

Advanced Science, EarlyView.
This Review critically connects structural recalcitrance, molecular modeling, solvent and catalyst design, pyrolysis, machine learning, reactor simulation, and FAIR digital infrastructure. Emphasis is placed on experimentally validated information transfer across scales, uncertainty and applicability domains, and the recycle, durability, techno ...
Abdullahi Bello Umar, Jiaxian Zheng, Xiangfeng Lin, Hongwu Liao, Haoqian Xu, Yufei Huang, Zaharaddeen Nasiru Garba, Adamu Uzairu, Weiwei Zhao, Zhanhui Yuan   +9 more
wiley   +1 more source

Intramolecular Nickel‐Catalyzed Reductive Coupling: Enantioselective Synthesis of Tetrahydroisoquinolines and Related Heterocycles

Angewandte Chemie, EarlyView.
The successful extension of the nickel‐catalyzed asymmetric coupling of polarized 1,3‐dienes with aldehydes to an intramolecular setting opens an efficient new entry into hydroxylated N‐heterocyclic compounds, most notably valuable tetrahydroisoquinolines.
Thilo Bender, Markus Leutzsch, Yannik Sell, Alois Fürstner   +3 more
wiley   +2 more sources

The Impact of Brewing Methods on the Quality of a Cup of Coffee

Beverages
A comprehensive overview is provided on factors and processes influencing the final quality of a cup of coffee, with an emphasis on the brewing method’s central role.
Alessandro Genovese, Nicola Caporaso, Antonietta Baiano   +2 more
doaj   +1 more source

Convenient Synthesis of 2-(1-Adamantyl)furans

, 2018
A simple method of obtaining 2-(1-adamantyl)furans using a smaller amount of catalyst, providing a higher yield of the target products, as well as the possibility of varying the substituents in the furan ring was developed.
Ida A. Lupanova, Valery V. Konshin, Vitaly A. Shcherbinin, Dzhamilya N. Konshina   +3 more
core   +1 more source

Inhibition of MEKK3 Prevents Cerebral Cavernous Malformation Progression Via Restoring Endothelial Integrity and Restricting Microglial Activation

Advanced Science, EarlyView.
In this study, we demonstrate that aberrant MEKK3 signaling in endothelial cells and microglia drives the progression of cerebral cavernous malformations (CCMs). Furthermore, we identify DPDH as a potent small‐molecule MEKK3 inhibitor with substantial therapeutic potential for CCM treatment.
Weiwei Zheng, Suyun Yu, Liwenyu Chen, Jing Ma, Peiliang Shen, Chang Yu, Xiaoqing Xin, Qiuhong Shen, Jing Chen, Song Ke, Hao Liu, Xiaobing Jiang, Ruogu Qi, Juming Yan, Jia Li, Jaesung P. Choi, Yin Lu, Yang Zhao   +17 more
wiley   +1 more source

Sustainable Access to N‐Heterocycles: One‐Pot Cascade Synthesis of Pyrroles From Bio‐Derived Furans

Angewandte Chemie, EarlyView.
Highly dispersed platinum (Pt) clusters on Brønsted acid‐rich HY zeolite enable a one‐pot cascade conversion of bio‐derived furans and nitroarenes into pyrroles. Highly dispersed Pt sites ensure selective nitro hydrogenation, while Pt nanoparticles promote undesired over‐hydrogenation.
Haifeng Qi, Germán López Robledo, Jianglin Duan, Yujing Ren, Kathrin Junge, Matthias Beller   +5 more
wiley   +2 more sources

Synthesis and Characterization of Three New Furan-Containing Terpyridine Derivatives

Molbank
Three new terpyridine derivatives which contain a pendant furan heterocycle have been prepared and characterized. The first two, 4′-(4,5-dimethylfuran-2-yl)-2,2′:6′,2″-terpyridine (1) and 4′-((1,3-dioxolan-2-yl)furan-2-yl)-2,2′:6′,2″-terpyridine (2), are
Jérôme Husson
doaj   +1 more source

In silico studies of 2,5-disubstituted furans as active antimalarial drug candidates

Bulletin of the National Research Centre, 2020
Backgrond In silico studies are essential techniques in the modern medicinal chemistry. QSAR modeling and molecular docking are important techniques in both drug discovery and development and have been successfully deployed in the field of medicinal ...
Aliyu Wappah Mahmud, Gideon Adamu Shallangwa, Adamu Uzairu   +2 more
doaj   +1 more source

Coral‐Biomimetic Structured Organic Electro‐Oxidations With Exceptional High‐Current Catalytic Performance

Advanced Science, EarlyView.
A strategy for energy‐efficient hydrogen production coupled with biomass valorization via organic electrooxidation reactions is reported. A bio‐inspired multiscale coral‐like heterostructure catalyst delivers record‐breaking OEOR performance enabled by a dual‐copper synergistic Cu+/Cu2+–Ni mechanism, establishing a universal architectural and ...
Chaoqun Pei, Tao Zhang, Congrui Yang, Yutao Tan, Zhengjie Chen, Yuyang Qian, Xiaoyu Wu, Xiaodi Liu, Xiong Liang, Jie Dong, Yongbin Guo, Haibo Ke, Wenqing Ruan, Zhenxuan Zhang, Tao Feng, Jing Peng, Jiang Ma, Baoan Sun   +17 more
wiley   +1 more source

Z‐Retentive Enantioselective Rh‐Catalyzed Hydroarylation of E,Z‐Dienes

Angewandte Chemie, EarlyView.
The Rh‐catalyzed hydroarylation of conjugated E,Z‐dienoates is found to proceed with high selectivity for addition to the E‐alkene unit. Mechanistic analysis of this Z‐retentive process points towards preferred binding of the E‐alkene unit to a Rh‐aryl species to give rise to the observed selectivity and that Rh‐enolate protonolysis to be turnover ...
Wesley McNutt, Hima Kozhummal, Abdullah Al‐Mashqbeh, Alex Brown, Rylan J. Lundgren   +4 more
wiley   +2 more sources