Results 31 to 40 of about 77,789 (337)

Small molecule therapeutics for COVID-19: repurposing of inhaled furosemide

open access: yesPeerJ, 2020
The novel coronavirus SARS-CoV-2 has become a global health concern. The morbidity and mortality of the potentially lethal infection caused by this virus arise from the initial viral infection and the subsequent host inflammatory response. The latter may
Zhiyu Wang   +13 more
semanticscholar   +1 more source

Different types of potassium transport linked to carbachol and γ-aminobutyric acid actions in rat sympathetic neurons [PDF]

open access: yes, 1984
Carbachol and γ-aminobutyric acid depolarize mammalian sympathetic neurons and increase the free extracellular K+-concentration. We have used double-barrelled ion-sensitive microelectrodes to determine changes of the membrane potential and of the free ...
Ballanyi, Klaus   +3 more
core   +1 more source

Association Between Furosemide Exposure and Clinical Outcomes in a Retrospective Cohort of Critically Ill Children

open access: yesFrontiers in Pediatrics, 2021
Furosemide is commonly prescribed in critically ill patients to increase the urine output and prevent fluid overload (FO) and acute kidney injury (AKI), but not supported by conclusive evidence.
Xiaomei Dai   +7 more
doaj   +1 more source

Continuous infusion versus intermittent bolus furosemide in heart failure NYHA III-IV [PDF]

open access: yes, 2017
The study was designed to investigate the therapeutic effect of Continuous Infusion (CI) and Intermittent Bolus (IB) administration of furosemide on patients with NYHA class III-IV heart failure hospitalized in Dr. Soetomo Hospital Surabaya.
Samirah, -, S. Sjamsiah, -, M. Yogiarto
core   +1 more source

Renal Nerve Deafferentation Attenuates the Fall in GFR during Intravenous Infusion of Furosemide in Anesthetized Rats

open access: yesKidney & Blood Pressure Research, 2020
Introduction: Furosemide reduces the glomerular filtration rate (GFR) and increases the renal vascular resistance (RVR) despite inhibiting tubuloglomerular feedback but increases proximal tubule pressure, renin release, and renal nerve activity ...
Magali Araujo   +3 more
doaj   +1 more source

Antihypertensive Effect Of Magnesium Sulfate (Cormagnesin®) And Its Combination With Furosemide On Conscious Spontaneously Hypertensive Rats [PDF]

open access: yesJournal of Biomedical & Clinical Research, 2015
The present study demonstrates the antihypertensive effect of magnesium sulfate (Cormagnesin®) and its combination with Furosemide on conscious spontaneously hypertensive rats (SHR) after intravenous infusion.
Katerina Simeonova   +2 more
doaj   +3 more sources

Intravenous Tolvaptan Sodium Phosphate Can Fail to Improve Fluid Overload Due to Heart Failure in Patients With Chronic Kidney Disease: A Case Report. [PDF]

open access: yesPharmacol Res Perspect
ABSTRACT Tolvaptan is widely used as an adjunct oral diuretic to loop and thiazide diuretics for the management of fluid overload in patients with congestive heart failure. Recently, tolvaptan sodium phosphate (TSP), a water‐soluble prodrug of tolvaptan, was developed for intravenous administration and has demonstrated efficacy and safety in clinical ...
Uno T   +10 more
europepmc   +2 more sources

Determinants of urinary output response to IV furosemide in acute kidney injury [PDF]

open access: yes, 2016
OBJECTIVES: This study assessed the determinants of urinary output response to furosemide in acute kidney injury; specifically, whether the response is related to altered pharmacokinetics or pharmacodynamics. DESIGN: Prospective cohort. SETTING:
Corcoran, Tomas B.   +29 more
core   +1 more source

Furosemide Use in Chronic Kidney Disease Patients

open access: yes, 2022
Chronic kidney disease is defined as kidney disease occurring for more than three months and is characterized by a decreasing glomerular filtration rate, reaching below 60 mL/min/1.73 m2 .
Hasmono, Didik   +3 more
core   +1 more source

Torsemide versus furosemide after acute decompensated heart failure: a retrospective observational study

open access: yesBMC Cardiovascular Disorders, 2019
Background Loop diuretics are recommended by clinical practice guidelines to treat volume overload in acute decompensated heart failure (ADHF). The effectiveness of switching furosemide to torsemide versus optimizing the furosemide dose following ADHF ...
Alaa Rahhal   +5 more
doaj   +1 more source

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