Results 51 to 60 of about 38,316 (201)

Metabolic abnormalities and reprogramming in cats with naturally occurring hypertrophic cardiomyopathy

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 1256-1270, April 2025.
Abstract Background and aims The heart is a metabolic organ rich in mitochondria. The failing heart reprograms to utilize different energy substrates, which increase its oxygen consumption. These adaptive changes contribute to increased oxidative stress.
Qinghong Li   +12 more
wiley   +1 more source

BCS Class IV Oral Drugs and Absorption Windows: Regional-Dependent Intestinal Permeability of Furosemide

open access: yesPharmaceutics, 2020
Biopharmaceutical classification system (BCS) class IV drugs (low-solubility low-permeability) are generally poor drug candidates, yet, ~5% of oral drugs on the market belong to this class.
Milica Markovic   +4 more
doaj   +1 more source

Epidemiology of hospitalized heart failure in France based on national data over 10 years, 2012–2022

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 1283-1294, April 2025.
Abstract Aims We aim to describe the incidence of HF hospitalization in France in the post‐pandemic era, the prevalence of HF cases and patients' characteristics, management and outcomes while focusing on sex, age and socio‐economic differences and to analyse time‐trends between 2012 and 2022.
Valérie Olié   +5 more
wiley   +1 more source

Prognostic role of TAPSE to PASP ratio in outpatients with left ventricular systolic dysfunction

open access: yesESC Heart Failure, Volume 12, Issue 2, Page 912-922, April 2025.
Abstract Aims Few data are available regarding the role of tricuspid annulus plane systolic excursion to pulmonary artery systolic pressure (TAPSE/PASP), a measurement of right ventricular to pulmonary artery coupling, in patients with chronic heart failure and left ventricular systolic dysfunction.
Mauro Riccardi   +9 more
wiley   +1 more source

Clinical Usefulness of Furosemide to Prevent Volume Overload Among Children and Young Adults with Transfusion-Dependent Thalassemia: A Randomized, Open-Label, Crossover Study

open access: yesJournal of Blood Medicine, 2020
Apichat Photia,1 Chanchai Traivaree,1 Chalinee Monsereenusorn,1 Piyarat Simthamnimit,2 Piya Rujkijyanont1 1Division of Hematology-Oncology, Department of Pediatrics, Phramongkutklao Hospital and College of Medicine, Bangkok, Thailand; 2Department of ...
Photia A   +4 more
doaj  

The added-up albumin enhances the diuretic effect of furosemide in patients with hypoalbuminemic chronic kidney disease: a randomized controlled study

open access: yesBMC Nephrology, 2012
Background Chronic kidney disease (CKD) with edema is a common clinical problem resulting from defects in water and solute excretion. Furosemide is the drug of choice for treatment. In theory, good perfusion and albumin are required for the furosemide to
Phakdeekitcharoen Bunyong   +1 more
doaj   +1 more source

Arterial Perivascular Space‐Mediated Solute Transport in the Mouse Brain

open access: yesExploration, EarlyView.
The mechanisms underlying solute clearance from the brain parenchyma remain debated, with competing hypotheses involving bulk cerebrospinal fluid flow versus perivascular transport. Using multimodal in vivo imaging and computational modeling in mice, this study demonstrates that arterial pulsation drives bidirectional solute movement within the ...
Shiyong Li   +9 more
wiley   +1 more source

A study of the efficacy of furosemide as a prophylaxis of acute renal failure in coronary artery bypass grafting patients: A clinical trial

open access: yesARYA Atherosclerosis, 2015
BACKGROUND: Renal failure is a frequent event after coronary artery bypass grafting (CABG). Hemodynamic alterations during surgery as well as the underlying disease are the predisposing factors.
Fatemeh Bayat   +3 more
doaj  

APROTININ INHIBITED ACUTE PANCREATITIS INDUCED BY HYDROCHLOROTHIAZIDE AND FUROSEMIDE IN EXPERIMENTIAL ANIMALS

open access: yesZagazig Journal of Pharmaceutical Sciences, 1997
The effect of the Kallikrein inhibitor, aprotinin, on hydrochlorothiazide and furosemide inducing pancreatitis has been studied in male rats. Treatment of animals with hydrochlorothiazide and furosemide for two weeks significantly increased serum lipase,
Hoda Mohamed   +3 more
doaj   +1 more source

Resource management and clinical outcomes during a national intravenous fluid shortage

open access: yesJournal of Hospital Medicine, EarlyView.
Abstract Background A natural disaster, Hurricane Helene, damaged a production facility supplying 60% of intravenous (IV) fluids in the United States. A nationwide IV fluid shortage followed. Objectives To evaluate a multifaceted IV fluid conservation intervention's effect on IV fluid utilization and clinical outcomes during the shortage.
Stacy A. Johnson   +3 more
wiley   +1 more source

Home - About - Disclaimer - Privacy