Results 81 to 90 of about 38,316 (201)

Urine chloride trajectory and relationship with diuretic response in acute heart failure

open access: yesESC Heart Failure
Aims Sodium excretion is a well‐defined marker used to assess diuretic response in acute heart failure (AHF). Despite a strong pathophysiological background, the role of urine chloride excretion has not been described and established yet.
Mateusz Guzik   +3 more
doaj   +1 more source

An eye on long‐duration spaceflight: Controversies, countermeasures and challenges

open access: yesExperimental Physiology, EarlyView.
Abstract Space flight‐associated neuroocular syndrome (SANS) is a consequence of long‐duration space flight and is detected in two‐thirds of astronauts. In‐flight, this can cause a change in the refraction of the eyes, requiring graded hypermetropic ‘superfocus adjustable’ glasses, optic nerve head oedema and choroidal folds.
Vincent Wing Sum Ng   +1 more
wiley   +1 more source

Traumatic arteriovenous fistula after ice axe injury 27 years ago: A case report

open access: yesExperimental Physiology, EarlyView.
Abstract We report a case of a traumatic arteriovenous fistula (AVF) between the superficial femoral artery and femoral vein that went undetected for 27 years following an ice axe injury during a climbing accident in 1997. An AVF is an abnormal connection between an artery and a vein, where blood flows directly from the high‐flow arterial system to the
Kate N. Thomas   +4 more
wiley   +1 more source

Therapeutic drug monitoring of antimicrobials in a paediatric setting: A retrospective single‐centre study

open access: yesBritish Journal of Clinical Pharmacology, Volume 92, Issue 8, Page 2723-2740, August 2026.
Aims Paediatric pharmacokinetics differ significantly from adults due to age‐related physiological changes, necessitating precise dose adjustments. However, data on therapeutic drug monitoring (TDM) implementation in paediatric setting remain limited.
Gianluca Gazzaniga   +20 more
wiley   +1 more source

Impact of empiric potassium supplementation on mortality, sudden cardiac arrest and stroke in furosemide initiators

open access: yesBritish Journal of Clinical Pharmacology, Volume 92, Issue 8, Page 2924-2936, August 2026.
Aim A prior non‐randomized study suggests that potassium supplementation may improve survival among furosemide initiators, and a randomized trial suggests that salt substitutes containing potassium might lower stroke risk. We conducted a retrospective cohort study using health‐care data to confirm or refute these associations among new users of ...
Thanh Phuong Pham Nguyen   +8 more
wiley   +1 more source

External validation of the BAN‐ADHF diuretic‐resistance score in the DAPA‐RESIST clinical trial

open access: yesBritish Journal of Clinical Pharmacology, Volume 92, Issue 8, Page 2960-2965, August 2026.
Diuretic resistance in worsening heart failure (HF) is associated with poorer outcomes and, although common, can be challenging to identify. The recently developed BAN‐ADHF score can potentially identify patients with worsening HF at risk of diuretic resistance.
Dominic M. Alfonso   +10 more
wiley   +1 more source

Optimized SPE‐HPLC‐FLD Method for the Simultaneous Determination of Olaparib, Propranolol, and Furosemide in Human Urine

open access: yesBiomedical Chromatography, Volume 40, Issue 8, August 2026.
ABSTRACT Olaparib belongs to the PARP inhibitors and is widely used as an anticancer drug. Due to frequent side effects, it is usually co‐administered with an antihypertensive, such as propranolol and/or an antidiuretic, such as furosemide. In this study, a highly sensitive HPLC‐FLD method was developed for the simultaneous determination of the three ...
Georgios Kamaris   +2 more
wiley   +1 more source

Microaxial Flow Pump Support as a Bridge to Transaxillary TAVI‐In‐TAVI in Cardiogenic Shock

open access: yesClinical Case Reports, Volume 14, Issue 8, August 2026.
ABSTRACT A 79‐year‐old man presented with cardiogenic shock due to severe degeneration of a prior transcatheter aortic valve. Temporary mechanical circulatory support with a transvalvular microaxial flow pump was initiated, resulting in rapid stabilization.
Matteo Orlandi   +9 more
wiley   +1 more source

Impella‐Assisted High‐Risk Percutaneous Coronary Intervention in Cardiogenic Shock With Low‐Flow, Low‐Gradient Aortic Stenosis and Multivessel Coronary Artery Disease: A Case Report

open access: yesClinical Case Reports, Volume 14, Issue 8, August 2026.
ABSTRACT Patients with cardiogenic shock, low‐flow, low‐gradient aortic stenosis, and multivessel coronary artery disease who are ineligible for surgery present a major therapeutic challenge. Percutaneous mechanical circulatory support may facilitate revascularization in this high‐risk population. A 69‐year‐old man presented after a mechanical fall and
Douni Roger   +3 more
wiley   +1 more source

A Rare Constellation of Peripartum Cardiomyopathy Manifesting With Multiple Thromboembolic Phenomena in a 15‐Year‐Old

open access: yesClinical Case Reports, Volume 14, Issue 8, August 2026.
ABSTRACT A 15‐year‐old postpartum primipara presented at 19 days with aphasia, right hemiparesis, chest pain, and dyspnea. Diagnostics confirmed concurrent cardioembolic stroke and pulmonary embolism secondary to peripartum cardiomyopathy (ejection fraction 29%).
Reuben E. Mkama   +39 more
wiley   +1 more source

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