Results 131 to 140 of about 451 (159)

Unsymmetrically substituted furoxans. Part 18. Smiles rearrangement in furoxan systems and in related furazans

Journal of the Chemical Society, Perkin Transactions 1, 2001
The preparation and the base-promoted Smiles rearrangement of phenylfurazans (series a), 3-phenylfuroxan (series b) and 4-phenylfuroxan (series c) bearing 2-hydroxyethylthio (1), 2-hydroxyethylsulfonyl (2), carbamoylmethylthio (3) and carbamoylmethylsulfonyl (4) functions at the hetero-ring are described.
BOSCHI D., BERTINARIA M., FRUTTERO R., CALVINO R., GASCO A., SORBA, Giovanni   +5 more
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Synthesis of carbohydrate furoxan derivatives

Journal of the Chemical Society, Chemical Communications, 1972
A route to carbohydrate furoxan derivatives has been developed which involves treatment of a carbohydrate α-keto toluene-p-sulphonate with hydroxylamine hydrochloride in aqueous pyridine, followed by treatment of the resultant oximino-pyridinium salt with sodium nitrite.
C. S. Wu, W. A. Szarek, J. K. N. Jones
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Unsymmetrically substituted furoxans. VII. A ¹³C NMR study of a series of isomeric pairs of furoxans and the structure of the two isomeric chloro‐phenyl‐furoxans

Journal of Heterocyclic Chemistry, 1982
AbstractThe structure of two isomeric chloro(phenyl)furoxans is proposed by comparison of their 13C nmr spectra with those of several unsymmetrically substituted furoxans and related furazans.
R. Calvino, R. Fruttero, A. Gasco, V. Mortarini, S. Aime   +4 more
openaire   +1 more source

New furoxan derivatives for the treatment of ocular hypertension

Bioorganic & Medicinal Chemistry Letters, 2017
A small series of water-soluble NO-donor furoxans bearing a basic center at the 4-position, having a wide lipophilic-hydrophilic balance range, and endowed with different NO-release capacities, were synthesized and characterized. Selected members were studied for their IOP-lowering activity in the transient ocular hypertensive rabbit model at 1% dose ...
Marco, Blangetti, Barbara, Rolando, Konstantin, Chegaev, Stefano, Guglielmo, Loretta, Lazzarato, Mariaconcetta, Durante, Emanuela, Masini, Nicoletta, Almirante, Elena, Bastia, Francesco, Impagnatiello, Roberta, Fruttero, Alberto, Gasco   +11 more
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Pharmacological Properties of Furoxans and Benzofuroxans: Recent Developments

Mini-Reviews in Medicinal Chemistry, 2005
The chemistry of furoxans (1, 2, 5-oxadiazole-2-oxides) and benzofuroxans (benzo[1, 2-c]1, 2, 5-oxadiazole-1-oxides) is very well known. These systems are widely used in organic chemistry as intermediate compounds for the synthesis of numerous heterocycles.
Hugo, Cerecetto, Williams, Porcal
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Benzofuroxan and Furoxan. Chemistry and Biology

2007
Since the middle of the 20th century, benzofuroxan and furoxan derivatives have been extensively studiedas bioactive compounds. Maybe the most relevant reported biological property has been related to its capabilityto release nitric oxide; moreover, other significant activities have been identified, such as antibacterial,antifungal, antiparasite ...
Hugo Cerecetto, Mercedes González
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The Chemistry of Furoxans

HETEROCYCLES, 1985
Wanda Sliwa, Antoni Thomas
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Dependence of the Decomposition Rate of Furoxanes on the Polarity of the Solvent

Russian Journal of Physical Chemistry B
The decomposition rates of diphenylfuroxane and a number of 4-nitro-3-alkyl-furoxanes in dilute solutions were measured by manometric and calorimetric methods. In no case, an increase in the reaction rate was detected with an increase in the polarity of the solvent, which corresponds to the absence of an increase in the dipole moment of the molecule ...
G. M. Nazin, A. I. Kazakov, A. V. Nabatova, L. L. Fershtat, A. A. Larin   +4 more
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Bis(cyclopropanecarbonyl)furoxan

The Journal of Organic Chemistry, 1968
Marguerite S. Chang, James U. Lowe
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On the isomerism of aryl-alkyl-furoxans: The molecular structure of methyl-p-bromophenyl-furoxans

Tetrahedron Letters, 1967
CALLERI M., FERRARIS G., VITERBO, Davide
openaire   +1 more source