Results 41 to 50 of about 281,828 (139)

Ligand-controlled product selectivity in palladium-catalyzed domino post-Ugi construction of (spiro)polyheterocycles

, 2016
A novel diversity-oriented access to (spiro)polyheterocycles possessing two adjacent quaternary carbon stereocenters is described. By combining an Ugi 4-CR with Pd-catalysis, the possible mode of cyclization is controlled by the appropriate choice of ...
Sharma, Upendra Kumar, Li, Zhenghua, Van der Eycken, Erik, Jacobs, Jeroen, Van Meervelt, Luc, Sharma, Nandini   +5 more
core   +1 more source

Molybdenum‐Catalyzed One‐Pot Multi‐Step Synthesis of N‐Polyheterocycles from Nitroarenes and Glycols

European Journal of Organic Chemistry, Volume 27, Issue 18, May 13, 2024.
A tandem process for the synthesis of N‐polyheterocycles from easily available nitroarenes catalyzed by a dioxomolybdenum(VI) complex is described, where the byproduct generated in the first step is incorporated into the final structure. A broad variety of nitrogenated compounds are synthesized in overall good yields in a one‐pot manner.
Sara Gómez‐Gil, Nuria Cases, Raquel Hernández‐Ruiz, Rubén Rubio‐Presa, Samuel Suárez‐Pantiga, María R. Pedrosa, Roberto Sanz   +6 more
wiley   +1 more source

Visible‐Light‐Driven Cyclizations

Advanced Synthesis &Catalysis, Volume 366, Issue 4, Page 635-697, February 20, 2024.
Abstract In recent years, the interest to develop cyclizations promoted by visible light has been gaining a lot of attention due to its sustainability aspect. In this review, we summarize the most important advances in this period by describing the methods used to generate different ring sizes, while focusing on the mechanistic details of these ...
Emilia Oueis, Mirella Elkadi, Ramon Rios
wiley   +1 more source

Synthesis and Conformational Analysis of Naphthoxazine-Fused Phenanthrene Derivatives

, 2020
The synthesis of new phenanthr[9,10-e][1,3]oxazines was achieved by the direct coupling of 9-phenanthrol with cyclic imines in the modified aza-Friedel–Crafts reaction followed by the ring closure of the resulting bifunctional aminophenanthrols ...
Heydenreich, Matthias (Dr.), Ferenc Fülöp, Fulop, Ferenc, Erich Kleinpeter, István Szatmári, Andreas Koch, Koch, Andreas (Dr.), Matthias Heydenreich, Khadija Belasri, Belasri, Khadija, Topal, Leila, Kleinpeter, Erich (Prof. Dr.), Szatmari, Istvan, Leila Topal   +13 more
core   +1 more source

Synthesis of Multiring Fused 2-Pyridones via a Nitrene Insertion Reaction: Fluorescent Modulators of α-Synuclein Amyloid Formation

, 2015
© 2015 American Chemical Society. An efficient, straightforward method for the synthesis of thiazolo-2-pyridone embedded peptidomimetic polyheterocycles via a catalyst-free, microwave-assisted, intramolecular C-H amination reaction is reported.
Pardeep Singh (294895), Singh, P., Almqvist, F., K. Syam Krishnan (1493944), Wittung Stafshede, Pernilla, Erik Chorell (813073), Chorell, E.,, Kindahl, T., Kindahl, T.,, Åden, J.,, Wittung-Stafshede, Pernilla, Almqvist, F.,, Chorell, E., Krishnan, K.S., Åden, J., Tomas Kindahl (1493947), Fredrik Almqvist (698391), Krishnan, K.S.,, Singh, P.,, Pernilla Wittung-Stafshede (166503), \uc5den, J., Jörgen Åden (1493950), Wittung Stafshede, Pernilla,   +22 more
core   +1 more source

Electro-generated ortho-quinoide intermediates: templates for feasible construction of a series of novel imidazo[2,1-b]thiazole derivatives through one-pot five-step domino hetero-annulation process

, 2014
A series of novel polycyclic structures, with an imidazothiazole central core, were successfully synthesized through the anodic oxidation of catechols in the presence of 2-imidazolidine thione, as nucleophiles in aqueous solution. The cyclic voltammetric
Abdolhamid Alizadeh, Tayyebeh Kanjouri, Mohammad M. Khodaei, Kanjouri, Tayyebeh, Khodaei, Mohammad M., Mustaffa Shamsuddin, Alizadeh, Abdolhamid, Shamsuddin, Mustaffa   +7 more
core   +1 more source

피리미딘이 포함된 다중고리골격 화합물들의 합성 및 응용 [PDF]

, 2016
학위논문 (박사)-- 서울대학교 대학원 : 화학부 유기화학전공, 2016. 8. 박승범.Identification of new small-molecule modulators is an indispensable research objective in chemical biology and drug discovery.
김희준
core  

Cu-catalyzed arylation of the amino group in the indazole ring: regioselective synthesis of pyrazolo-carbazoles

, 2015
Cu(II)-catalyzed cross-coupling of various aryl boronic acids with 5 and 6-amino indazoles has resulted in (arylamino)-indazoles. These (arylamino)-indazoles have been utilized in synthesizing medicinally important pyrazole-fused carbazoles via Pd(II ...
Dhaked, Devendra K., Bharatam, Prasad V., Anil Kumar, K., Kannaboina, Prakash, Vishwakarma, Ram A., Das, Parthasarathi   +5 more
core   +1 more source

Ru(II)-Catalyzed [4 + 2]-Annulation of 2‑Alkenyl/Arylimidazoles with N-Substituted Maleimides and 1,4-Naphthoquinones: Access to Imidazo-Fused Polyheterocycles

Synthesis of imidazo-fused polyheterocyclic molecular frameworks, viz. imidazo[1,2-a]pyrrolo[3,4-e]pyridines, imidazo[2,1-a]pyrrolo[3,4-c]isoquinolines, and benzo[g]imidazo[1,2-a]quinoline-6,11-diones, has been achieved by the ruthenium(II)-catalyzed [4 +
Prakash N. Swami (16943696), Krishnan Rangan (2389432), Dhananjay S. Nipate (17895595), Anil Kumar (105720), Neha Meena (14615885)   +4 more
core   +2 more sources

Synthesis of New Polyheterocyclic Pyrrolo[3,4-b]pyridin-5-ones via an Ugi-Zhu/Cascade/Click Strategy. [PDF]

Molecules, 2023
Blanco-Carapia RE, Aguilar-Rangel EA, Rincón-Guevara MA, Islas-Jácome A, González-Zamora E.   +4 more
europepmc   +1 more source