Results 91 to 100 of about 3,721,647 (391)
Evolutionary interplay between viruses and R‐loops
FEBS Letters, EarlyView.Viruses interact with specialized nucleic acid structures called R‐loops to influence host transcription, epigenetic states, latency, and immune evasion. This Perspective examines the roles of R‐loops in viral replication, integration, and silencing, and how viruses co‐opt or avoid these structures.
Zsolt Karányi +4 more
wiley +1 more source
Sea-detecting X-band Radar and Data Acquisition Program
Leida xuebao, 2019 To meet the radar data requirements of target detection technology research and address the lack of publicly available sea-detecting radar data, a data-sharing program for sea-detecting radar is proposed herein.
LIU Ningbo +7 more
doaj +1 more source
Modern Physics Letters A, 1991 We discuss when and how the Verlinde dimensions of a rational conformal field theory can be expressed as correlation functions in a topological LG theory. It is seen that a necessary condition is that the RCFT fusion rules must exhibit an extra symmetry. We consider two particular perturbations of the Grassmannian superpotentials.
openaire +2 more sources
Disruption of SETD3‐mediated histidine‐73 methylation by the BWCFF‐associated β‐actin G74S mutation
FEBS Letters, EarlyView.The β‐actin G74S mutation causes altered interaction of actin with SETD3, reducing histidine‐73 methylation efficiency and forming two distinct actin variants. The variable ratio of these variants across cell types and developmental stages contributes to tissue‐specific phenotypical changes. This imbalance may impair actin dynamics and mechanosensitive
Anja Marquardt +8 more
wiley +1 more source
Purification tags markedly affect self‐aggregation of CPEB3
FEBS Letters, EarlyView.Although recombinant proteins are used to study protein aggregation in vitro, uncleaved tags can interfere with accurate interpretation. Our findings demonstrate that His₆‐GFP and His₁₂ tags significantly affect liquid droplet and amyloid fibril formation in the intrinsically disordered region (IDR) of mouse cytoplasmic polyadenylation element‐binding ...
Harunobu Saito +6 more
wiley +1 more source
Dynamical nucleus-nucleus potential at short distances
, 2010 The dynamical nucleus-nucleus potentials for fusion reactions 40Ca+40Ca, 48Ca+208Pb and 126Sn+130Te are studied with the improved quantum molecular dynamics (ImQMD) model together with the extended Thomas-Fermi approximation for the kinetic energies of ...
Ning Wang +4 more
core +1 more source
Current Opinion in Cell Biology, 2002 Fusion of biological membranes is governed by physical principles but it is unclear whether the transition states are primarily determined by lipid physics or by protein-lipid interactions. Recent advances in the field include the physical description of bilayer fusion, particularly new models beyond continuum models and the role of the SNARE proteins.
Jahn, R., Grubmueller, H.
openaire +4 more sources
FEBS Letters, EarlyView.This study reveals how prime editing guide RNA (pegRNA) secondary structure and reverse transcriptase template length affect prime editing efficiency in correcting the phospholamban R14del cardiomyopathy‐associated mutation. Insights support the design of structurally optimized enhanced pegRNAs for precise gene therapy.
Bing Yao +7 more
wiley +1 more source
Track Segment Association via track graph representation learning
IET Radar, Sonar & Navigation, 2021 Traditional Track Segment Association (TSA) methods used track position vectors or other track information to get association results. However, simply extracting the track position information to form track vectors will lead to the loss of irregular ...
Wei Xiong +5 more
doaj +1 more source
FEBS Letters, EarlyView.In the adult T‐cell leukemia/lymphoma (ATL) cell line ED, the human T‐cell leukemia virus type 1 (HTLV‐1) provirus was integrated into the intron of the ift81 gene in the antisense orientation. Despite this integration, both the intact ift81 and the viral oncogene hbz were simultaneously expressed, likely due to the functional insufficiency of viral ...
Mayuko Yagi +5 more
wiley +1 more source