Results 131 to 140 of about 3,721,647 (391)

Multidimensional OMICs reveal ARID1A orchestrated control of DNA damage, splicing, and cell cycle in normal‐like and malignant urothelial cells

open access: yesMolecular Oncology, EarlyView.
Loss of the frequently mutated chromatin remodeler ARID1A, a subunit of the SWI/SNF cBAF complex, results in less open chromatin, alternative splicing, and the failure to stop cells from progressing through the cell cycle after DNA damage in bladder (cancer) cells. Created in BioRender. Epigenetic regulators, such as the SWI/SNF complex, with important
Rebecca M. Schlösser   +11 more
wiley   +1 more source

ShcD adaptor protein drives invasion of triple negative breast cancer cells by aberrant activation of EGFR signaling

open access: yesMolecular Oncology, EarlyView.
We identified adaptor protein ShcD as upregulated in triple‐negative breast cancer and found its expression to be correlated with reduced patient survival and increased invasion in cell models. Using a proteomic screen, we identified novel ShcD binding partners involved in EGFR signaling pathways.
Hayley R. Lau   +11 more
wiley   +1 more source

Targeting the AKT/mTOR pathway attenuates the metastatic potential of colorectal carcinoma circulating tumor cells in a murine xenotransplantation model

open access: yesMolecular Oncology, EarlyView.
Dual targeting of AKT and mTOR using MK2206 and RAD001 reduces tumor burden in an intracardiac colon cancer circulating tumor cell xenotransplantation model. Analysis of AKT isoform‐specific knockdowns in CTC‐MCC‐41 reveals differentially regulated proteins and phospho‐proteins by liquid chromatography coupled mass spectrometry. Circulating tumor cells
Daniel J. Smit   +19 more
wiley   +1 more source

Generation and transport of atomic lithium during the exposure of liquid metals to hot plasmas in TJ-II

open access: yesNuclear Materials and Energy, 2018
A full campaign of comparative Li/LiSn/Sn testing has been initiated in TJ-II stellarator plasmas. Solid and liquid samples of the three candidates, in a Capillary Porous System (CPS) arrangement, have been exposed to the edge plasma and the associated ...
F.L Tabarés   +9 more
doaj  

Experimental results of maritime moving target detection based on passive bistatic radar using non-cooperative radar illuminators

open access: yesThe Journal of Engineering, 2019
A signal processing method of passive bistatic radar using non-cooperative pulse radar illuminators is proposed. The proposed method estimates unknown parameters of transmitting radar signal from direct-path signal, and uses estimated parameters for ...
Song Jie   +3 more
doaj   +1 more source

Fusion soul

open access: yes
If you live for my blood, you will die for blood. If you live for blood lust, you will die by a blood frenzy. Blidium udnae lidium, proesckae. Bleed or learn, pigs. From me, Lachlan Thomas Wilke, then became known as Lachlan Thomas Madden, which then I knew myself as Loki Lindii.
openaire   +15 more sources

Inhibitor of DNA binding‐1 is a key regulator of cancer cell vasculogenic mimicry

open access: yesMolecular Oncology, EarlyView.
Elevated expression of transcriptional regulator inhibitor of DNA binding 1 (ID1) promoted cancer cell‐mediated vasculogenic mimicry (VM) through regulation of pro‐angiogenic and pro‐cancerous genes (e.g. VE‐cadherin (CDH5), TIE2, MMP9, DKK1). Higher ID1 expression also increased metastases to the lung and the liver.
Emma J. Thompson   +11 more
wiley   +1 more source

The cell fusion-free vegetable list helps organic farmers to find suitable cultivars (Liveseed Practice Abstract) [PDF]

open access: yes, 2019
You can download the list for free in German and French: https://www.fibl.org/en/shop-en/1671-zf-freie-sorten.html Further Information: FiBL breeding manual https://www.fibl.org/en/shop-en/1202-plant-breeding.html - IFOAM-strategy on artificial CMS
Kimmel, Thomas   +2 more
core  

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