Results 91 to 100 of about 42,805 (305)
Fusion blanket design and optimization techniques. [PDF]
, 2005 In fusion reactors, the blanket design and its characteristics have a major impact on the reactor performance, size, and economics. The selection and arrangement of the blanket materials, dimensions of the different blanket zones, and different requirements of the selected materials for a satisfactory performance are the main parameters, which define ...
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Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions
FEBS Letters, EarlyView.We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva +10 more
wiley +1 more source
Mixed convection in a downward flow in a vertical duct with strong transverse magnetic field
, 2018 The downward flow in a vertical duct with one heated and three thermally insulated walls is analyzed numerically using the two-dimensional approximation valid in the asymptotic limit of an imposed strong transverse magnetic field.
Zhang, Xuan, Zikanov, Oleg
core +1 more source
PICALM::MLLT10 translocated leukemia
FEBS Letters, EarlyView.This comprehensive review of PICALM::MLLT10 translocated acute leukemia provides an in‐depth review of the structure and function of CALM, AF10, and the fusion oncoprotein (1). The multifaceted molecular mechanisms of oncogenesis, including nucleocytoplasmic shuttling (2), epigenetic modifications (3), and disruption of endocytosis (4), are then ...
John M. Cullen +7 more
wiley +1 more source
Cell wall target fragment discovery using a low‐cost, minimal fragment library
FEBS Letters, EarlyView.LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan +5 more
wiley +1 more source
Vanadium Alloys for Fusion Blanket Applications
MATERIALS TRANSACTIONS, 2005 Vanadium alloys are attractive candidate structural materials for breeding blanket of fusion reactors because of their low activation properties and high temperature strength. Studies on various blanket designs are being carried out using vanadium alloys as structural materials and liquid lithium or molten salt Flibe as breeding and coolant materials ...
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Multivariable optimization of fusion reactor blankets [PDF]
, 1984 The optimization problem consists of four key elements: a figure of merit for the reactor, a technique for estimating the neutronic performance of the blanket as a function of the design variables, constraints on the design variables and neutronic performance, and a method for optimizing the figure of merit subject to the constraints. The first reactor
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Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Recent Designs for Advanced Fusion Reactor Blankets [PDF]
Fusion Technology, 1994 A series of reactor design studies based on the Tokamak configuration have been carried out under the direction of Professor Robert Conn of UCLA. They are called ARIES-I through IV. The key mission of these studies is to evaluate the attractiveness of fusion assuming different degrees of advancement in either physics or engineering development.
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Molecular Oncology, EarlyView.This study explores salivary RNA for breast cancer (BC) diagnosis, prognosis, and follow‐up. High‐throughput RNA sequencing identified distinct salivary RNA signatures, including novel transcripts, that differentiate BC from healthy controls, characterize histological and molecular subtypes, and indicate lymph node involvement.
Nicholas Rajan +9 more
wiley +1 more source