Results 251 to 260 of about 7,331,516 (404)

Development of a Novel Bifunctional Anti-CD47 Fusion Protein with Improved Efficacy and a Favorable Safety Profile. [PDF]

Mol Cancer Ther
Matar S, Skah S, Diomande LE, Buss T, Hagland HR, Yadav A, Forstrøm RJ, Dalhus B, Hestdal K, Pettersen RD, Richartz N.   +10 more
europepmc   +1 more source

Expression of transforming region of Moloney murine sarcoma virus in Escherichia coli as a fusion protein with small tumor antigen of polyoma virus.

, 1982
Daniel J. Donoghue, Tony Hunter
openalex   +1 more source

Activation of SIRT1 Reduces Renal Tubular Epithelial Cells Fibrosis in Hypoxia Through SIRT1‐FoxO1‐FoxO3‐Autophagy Pathway

Advanced Biology, EarlyView.
Hypoxia promotes the epithelial‐mesenchymal transition (EMT) of renal tubular epithelial cells via the SIRT1‐FoxO1‐FoxO3‐autophagy pathway, thereby resulting in the fibrosis of renal tubular epithelial cells. Activation of SIRT1 or induction of autophagy inhibits this process, alleviating hypoxia‐induced fibrosis.
Guangyu Wang, Lijuan Zhang, Jiaorong Tan, Fei Li, Yishan Jin, Limei He, Xin Yang   +6 more
wiley   +1 more source

Hydrophobic residue substitutions enhance the stability and <i>in vivo</i> immunogenicity of respiratory syncytial virus fusion protein. [PDF]

J Virol
Song Q, Yang H, Zhu H, Hu Y, Shen W, Cheng H, Cai J, Qiu M, Li Y, Li Y, Ye W, Wang Y, Tang W.   +12 more
europepmc   +1 more source

Parasitic nematode vaccine for human and animal protection fusion protein expression

, 1989

openalex   +1 more source

Targeting RAGE with Nanobodies for Molecular Imaging of Cancers and Alzheimer's Disease

Advanced Biology, EarlyView.
RAGE‐specific nanobodies were isolated via phage display and characterized by ELISA, cell ELISA, and SPR. In vivo imaging in renal carcinoma and Alzheimer's disease mouse models demonstrated that NbF8, the highest‐affinity clone, selectively targeted RAGE‐overexpressing tumors and brain tissues, highlighting its potential as a molecular imaging agent ...
Guangfeng Liang, Fujing Wang, Wei Xiong, Guangwei Shi, Junling Yuan, Yang Li, Hongyan Zhang, Yanmei Xing, Shan Jin, Kongjun Yang, Zhongliang Dai, Jichao Sun, Zhijie Li, Jianhong Wang   +13 more
wiley   +1 more source

Immunogenicity and cellular response of a herpes zoster virus gEgI fusion protein adjuvanted with CpG-emulsion in mice. [PDF]

J Nanobiotechnology
Zhang S, Zeng Y, Cui L, Zhang Y, Chen T, Xue W, Wang H, Liu H, Zhang Y, Chen L, Zhou L, Xiong Y, Zheng Q, Yu H, Cheng T, Zhang J, Gu Y, Li T, Xia N, Li S.   +19 more
europepmc   +1 more source

Pharmacokinetics and brain uptake in the rhesus monkey of a fusion protein of arylsulfatase a and a monoclonal antibody against the human insulin receptor

Biotechnology and Bioengineering, 2013
R. Boado, Jeff Zhiqiang Lu, E. Hui, R. Sumbria, W. Pardridge   +4 more
semanticscholar   +1 more source

The Potential for Extracellular Vesicles in Nanomedicine: A Review of Recent Advancements and Challenges Ahead

Advanced Biology, EarlyView.
Extracellular vesicles (EVs) play a dual role in diagnostics and therapeutics, offering innovative solutions for treating cancer, cardiovascular, neurodegenerative, and orthopedic diseases. This review highlights EVs’ potential to revolutionize personalized medicine through specific applications in disease detection and treatment.
Farbod Ebrahimi, Anjali Kumari, Samaneh Ghadami, Saqer Al Abdullah, Kristen Dellinger   +4 more
wiley   +1 more source

Combinatorial treatment with upadacitinib abrogates systemic toxicity of a tumor-targeted IL-2 fusion protein. [PDF]

J Immunother Cancer
Rotta G, Prodi E, Seehusen F, Bocci M, Prisco F, Gilardoni E, Comacchio C, Halin C, Puca E, Neri D, Dakhel Plaza S.   +10 more
europepmc   +1 more source