Results 251 to 260 of about 1,121,449 (385)

Early metastasis is characterized by Gr1+ cell dysregulation and is inhibited by immunomodulatory nanoparticles

Molecular Oncology, EarlyView.
Breast cancer metastasis is associated with myeloid cell dysregulation and the lung‐specific accumulation of tumor‐supportive Gr1+ cells. Gr1+ cells support metastasis, in part, through a CHI3L1‐mediated mechanism, which can be targeted and inhibited with cargo‐free, polymeric nanoparticles.
Jeffrey A. Ma, Sophia M. Orbach, Kate V. Griffin, Kathryn Kang, Yining Zhang, Rebecca S. Pereles, Ian A. Schrack, Guillermo Escalona, Jacqueline S. Jeruss, Lonnie D. Shea   +9 more
wiley   +1 more source

The HELP-UnaG Fusion Protein as a Bilirubin Biosensor: From Theory to Mature Technological Development. [PDF]

Molecules
Sist P, Urbani R, Tramer F, Bandiera A, Passamonti S.   +4 more
europepmc   +1 more source

Production of Specific Antibodies against Human Cholesteryl Ester Transfer Protein Using C-Terminal Active Peptide Obtained by Fusional Expression of Cholesteryl Ester Transfor Protein cDNA

, 1994
Nam Wook Jeong, Woo H. Yoon, Myung‐Sook Choi, Tae‐Lin Huh, Chang Soon Yoon, Ju‐Won Kwak, Song‐Hae Bok, Yong Bok Park   +7 more
openalex   +1 more source

Membrane fusion of Semliki Forest virus involves homotrimers of the fusion protein [PDF]

, 1992
J M Wahlberg, Romke Bron, Jan Wilschut, Henrik Garoff   +3 more
openalex   +1 more source

Measuring the capacity of yeast for surface display of cell wall‐anchored protein isoforms by using β‐lactamase as a reporter enzyme

FEBS Open Bio, Volume 15, Issue 4, Page 573-579, April 2025.
Yeast surface display (YSD) uses genetically modified yeast to immobilize recombinant enzymes on the cell surface. To quantify the efficiency of YSD, β‐lactamase was fused to selected cell wall proteins and enzyme activity was measured spectrophotometrically at 482 nm using nitrocefin as substrate. This system enables the monitoring of enzyme activity,
Tea Martinić Cezar, Antonia Paić, Stefani Prekpalaj, Renata Teparić, Bojan Žunar, Igor Stuparević   +5 more
wiley   +1 more source

PLZF-RAR alpha fusion proteins generated from the variant t(11;17)(q23;q21) translocation in acute promyelocytic leukemia inhibit ligand-dependent transactivation of wild-type retinoic acid receptors. [PDF]

, 1994
Z Chen, Fabien Guidez, Philippe Rousselot, Anissa Agadir, S J Chen, Z Y Wang, L Degos, Arthur Zelent, Susannah Waxman, Christine Chomienne   +9 more
openalex   +1 more source

Protein crystallization and structure determination at room temperature in the CrystalChip

FEBS Open Bio, Volume 15, Issue 4, Page 532-541, April 2025.
This protocol describes the implementation of a simple and user‐friendly microfluidic device called CrystalChip that allows the production of crystals by the counter‐diffusion method and their in situ analysis by serial crystallography. As an illustration, it is applied to determine the 3D structure of three proteins from data collected at room ...
Petr Pachl, Léna Coudray, Romain Vincent, Léa Nilles, Hélène Scheer, Christophe Ritzenthaler, Adéla Fejfarová, Pavlína Řezáčová, Sylvain Engilberge, Claude Sauter   +9 more
wiley   +1 more source

Recombinant CD80 fusion protein combined with discoidin domain receptor 1 inhibitor for cancer treatment. [PDF]

Appl Microbiol Biotechnol
Wang S, Hu P, Zhang X, Fan J, Zou J, Hong W, Huang X, Pan D, Chen H, Ju D, Zhu YZ, Ye L.   +11 more
europepmc   +1 more source

Vectorial apical delivery and slow endocytosis of a glycolipid-anchored fusion protein in transfected MDCK cells. [PDF]

, 1990
Michael P. Lisanti, Ingrid W. Caras, Thierry Gilbert, David K. Hanzel, E Rodriguez-Boulan   +4 more
openalex   +1 more source

NPC1 promotes the progression of hepatocellular carcinoma by mediating the accumulation of neutrophils into the tumor microenvironment

FEBS Open Bio, Volume 15, Issue 4, Page 661-673, April 2025.
Compared to normal tissues, NPC1 expression is significantly elevated in hepatocellular carcinoma tissues. Our findings indicate that NPC1 plays a key role in regulating neutrophil recruitment within the tumor, which is a critical factor in the progression of hepatocellular carcinoma and is closely linked to poor patient outcomes.
Songhai Yang, Jiangming Chen, Kun Xie, Fubao Liu   +3 more
wiley   +1 more source