Results 261 to 270 of about 1,121,449 (385)

Hematopoietic effects of a granulocyte-macrophage colony-stimulating factor/interleukin-3 fusion protein [PDF]

open access: bronze, 1991
Douglas E. Williams, Linda Park
openalex   +1 more source

Real‐world genomic landscape of colon and rectal cancer

open access: yesFEBS Open Bio, Volume 15, Issue 4, Page 674-685, April 2025.
We confirmed enrichment of RTK alterations in patients with RAS/BRAF‐wt tumors and of PI3K pathway alterations in RAS/BRAF‐altered tumors with 51 982 real‐world tissue comprehensive genomic profiling (CGP) samples in CRC. In a subset of 140 patients with both tissue and liquid results, the sensitivity of liquid for results found by tissue was 100% when
Markus Schulze   +7 more
wiley   +1 more source

Combinatorial generation of variable fusion proteins in the Ewing family of tumours.

open access: bronze, 1993
Jessica Zucman‐Rossi   +9 more
openalex   +1 more source

Cost‐effective and simple flow cytometry quantification of receptor‐mediated autophagy using fluorescent tagging

open access: yesFEBS Open Bio, Volume 15, Issue 4, Page 587-598, April 2025.
Mitophagy, the selective degradation of damaged mitochondria, is crucial for cellular health and function. This study introduces a rapid and efficient flow cytometry method using GFP‐BNIP3L/NIX to accurately quantify mitophagy. Our approach can be adapted to use any fluorescent‐tagged selective autophagy receptor, enabling direct and rapid analysis of ...
Mija Marinković   +3 more
wiley   +1 more source

The N-terminal domain of a rab protein is involved in membrane-membrane recognition and/or fusion. [PDF]

open access: bronze, 1994
Olivia Steele‐Mortimer   +5 more
openalex   +1 more source

Dexmedetomidine suppresses glucose‐stimulated insulin secretion in pancreatic β‐cells

open access: yesFEBS Open Bio, Volume 15, Issue 4, Page 634-646, April 2025.
Dexmedetomidine decreases insulin release and affects glucose metabolism; however, the specific mechanism remains largely unknown. This study shows clinically relevant doses of dexmedetomidine suppressed glucose‐stimulated insulin secretion. There was no significant difference in oxygen consumption rate, intracellular ATP levels, or caspase‐3/7 ...
Munenori Kusunoki   +5 more
wiley   +1 more source

Home - About - Disclaimer - Privacy