Quality by design for transient RBD-Fc fusion protein production in Chinese hamster ovary cells. [PDF]
Jivapetthai A+2 more
europepmc +1 more source
Hematopoietic effects of a granulocyte-macrophage colony-stimulating factor/interleukin-3 fusion protein [PDF]
Douglas E. Williams, Linda Park
openalex +1 more source
Real‐world genomic landscape of colon and rectal cancer
We confirmed enrichment of RTK alterations in patients with RAS/BRAF‐wt tumors and of PI3K pathway alterations in RAS/BRAF‐altered tumors with 51 982 real‐world tissue comprehensive genomic profiling (CGP) samples in CRC. In a subset of 140 patients with both tissue and liquid results, the sensitivity of liquid for results found by tissue was 100% when
Markus Schulze+7 more
wiley +1 more source
Administration of a Recombinant Fusion Protein of IFN-γ and CD154 Inhibited the Infection of Chicks with Salmonella enterica. [PDF]
Zhang J+7 more
europepmc +1 more source
Combinatorial generation of variable fusion proteins in the Ewing family of tumours.
Jessica Zucman‐Rossi+9 more
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Mitophagy, the selective degradation of damaged mitochondria, is crucial for cellular health and function. This study introduces a rapid and efficient flow cytometry method using GFP‐BNIP3L/NIX to accurately quantify mitophagy. Our approach can be adapted to use any fluorescent‐tagged selective autophagy receptor, enabling direct and rapid analysis of ...
Mija Marinković+3 more
wiley +1 more source
The self-renewal function of Oct-4 can be replaced by the EWS-Oct-4 fusion protein in embryonic stem cells. [PDF]
Lee EJ, Sun R, Kim J.
europepmc +1 more source
The N-terminal domain of a rab protein is involved in membrane-membrane recognition and/or fusion. [PDF]
Olivia Steele‐Mortimer+5 more
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Dexmedetomidine suppresses glucose‐stimulated insulin secretion in pancreatic β‐cells
Dexmedetomidine decreases insulin release and affects glucose metabolism; however, the specific mechanism remains largely unknown. This study shows clinically relevant doses of dexmedetomidine suppressed glucose‐stimulated insulin secretion. There was no significant difference in oxygen consumption rate, intracellular ATP levels, or caspase‐3/7 ...
Munenori Kusunoki+5 more
wiley +1 more source
Modification of Fc-fusion protein structures to enhance efficacy of cancer vaccine in plant expression system. [PDF]
Lim S+6 more
europepmc +1 more source