Results 281 to 290 of about 1,121,449 (385)

Mapping Hsp104 interactions using cross‐linking mass spectrometry

FEBS Open Bio, EarlyView.
This study examines how cross‐linking mass spectrometry can be utilized to analyze ATP‐induced conformational changes in Hsp104 and its interactions with substrates. We developed an analytical pipeline to distinguish between intra‐ and inter‐subunit contacts within the hexameric homo‐oligomer and discovered contacts between Hsp104 and a selected ...
Kinga Westphal, Karolina Michalska, Andrzej Joachimiak, Lukasz A. Joachimiak   +3 more
wiley   +1 more source

Antiviral activity of an ACE2-Fc fusion protein against SARS-CoV-2 and its variants. [PDF]

PLoS One
Bermúdez-Abreut E, Fundora-Barrios T, Hernández Fernández DR, Noa Romero E, Fraga-Quintero A, Casadesús Pazos AV, Fernández-Marrero B, Plasencia Iglesias CA, Clavel Pérez M, Sosa Aguiar K, Sánchez-Ramírez B, Hernández T.   +11 more
europepmc   +1 more source

Transforming growth factor alpha-Pseudomonas exotoxin fusion protein prolongs survival of nude mice bearing tumor xenografts.

, 1990
David Heimbrook, Steven M. Stirdivant, Janet Ahern, N L Balishin, Denis R. Patrick, George M. Edwards, Deborah Defeo-Jones, D J FitzGerald, Ira Pastan, Allen Oliff   +9 more
openalex   +1 more source

A non‐fluorescent immunohistochemistry method for measuring autophagy flux using MAP1LC3/LC3 and SQSTM1 as core markers

FEBS Open Bio, EarlyView.
We introduce an immunohistochemistry method to measure autophagy flux, highlighting the active degradation and recycling of cellular waste. This cost‐effective approach uses tissue samples to track key markers like LC3 and SQSTM1, revealing how cells maintain health or respond to diseases such as cancer. It bridges the gap between research and clinical
Shahla Shojaei, Amir Barzegar Behrooz, Marco Cordani, Mahmoud Aghaei, Negar Azarpira, Daniel J. Klionsky, Saeid Ghavami   +6 more
wiley   +1 more source

Intranasal spike and nucleoprotein fusion protein-based vaccine provides cross-protection and reduced transmission against SARS-CoV-2 variants. [PDF]

NPJ Vaccines
Lakhrif Z, Poupée-Beaugé A, Boursin F, Ducournau C, Lantier L, Moiré N, Carpentier R, Rossignol C, Maquart M, Jospin F, Merat L, Caul-Futy M, Yazdanpanah Y, Bouakane A, Riou M, Touzé A, Eléouët JF, Richard CA, Helle F, Le Poder S, Klonjkowski B, Meunier N, Zientara S, Paul S, Mévélec MN, Aubrey N, Epardaud M, Dimier-Poisson I.   +27 more
europepmc   +1 more source

INHIBITION OF HIV-1 RNA PRODUCTION BY THE DIPHTHERIA TOXIN-RELATED IL-2 FUSION PROTEINS DAB486IL-2 AND DAB389IL-2

, 1992
Zhang Lin, Cory A. Waters, Jean Nichols, Clyde S. Crumpacker   +3 more
openalex   +1 more source

Establishment and biological characterization of radioresistant colorectal cancer cell lines

FEBS Open Bio, EarlyView.
Under ionizing radiation exposure, radiation‐sensitive cancer cells exhibit oxidative stress and DNA damage, while radiation‐resistant cancer cells exhibit strong antioxidant properties and DNA damage repair. Radiotherapy resistance is a major cause of recurrence and metastasis in colorectal cancer (CRC).
Tian‐Yin Qu, Qing Dai, Jing Leng, Lin Fang, Jing‐Jing Ma, Rui Chen, Che Chen, Peng‐Fei Ran, Wen‐Wen Zhou, Chang Liu, Huang‐Fei Yu   +10 more
wiley   +1 more source

Expression of an epidermal growth factor-transdermal peptide fusion protein in <i>Arabidopsis thaliana</i> and its therapeutic effects on skin barrier repair. [PDF]

Front Plant Sci
Yu G, Lin S, Huang X, Gao S, Song C, Khalilov F, Chen Q, Issaro N, Xiao J, Xu X, Wang J, Zhao W, Wang Y, Xu N.   +13 more
europepmc   +1 more source

Localization of chromatophore proteins of Rhodobacter sphaeroides. I. Rapid Ca(2+)-induced fusion of chromatophores with phosphatidylglycerol liposomes for proteinase delivery to the luminal membrane surface.

, 1991
Rolf Theiler, Robert A. Niederman
openalex   +1 more source

Bioengineering facets of the tumor microenvironment in 3D tumor models: insights into cellular, biophysical and biochemical interactions

FEBS Open Bio, EarlyView.
The tumor microenvironment is a dynamic, multifaceted complex system of interdependent cellular, biochemical, and biophysical components. Three‐dimensional in vitro models of the tumor microenvironment enable a better understanding of these interactions and their impact on cancer progression and therapeutic resistance.
Salma T. Rafik, Deniz Bakkalci, Alexander J. MacRobert, Umber Cheema   +3 more
wiley   +1 more source