Results 21 to 30 of about 7,331,516 (404)
Avian Paramyxovirus Type 1 in Egypt: Epidemiology, Evolutionary Perspective, and Vaccine Approach
Frontiers in Veterinary Science, 2021 Avian orthoavulavirus 1, formerly known as avian paramyxovirus type-1 (APMV-1), infects more than 250 different species of birds. It causes a broad range of clinical diseases and results in devastating economic impact due to high morbidity and mortality ...
Shimaa M. G. Mansour +8 more
doaj +1 more source
Cyanobacterial Production of Biopharmaceutical and Biotherapeutic Proteins
Frontiers in Plant Science, 2020 Efforts to express human therapeutic proteins in photosynthetic organisms have been described in the literature. Regarding microalgae, most of the research entailed a heterologous transformation of the chloroplast, but transformant cells failed to ...
Nico Betterle +2 more
doaj +1 more source
Frontiers in Cell and Developmental Biology, 2021 We describe, for the first time, a new splice variant of the human TGF-β type II receptor (TβRII). The new transcript lacks 149 nucleotides, resulting in a frameshift and the emergence of an early stop codon, rendering a truncated mature protein of 57 ...
Marcela Soledad Bertolio +11 more
doaj +1 more source
Fusion mechanism of 2019-nCoV and fusion inhibitors targeting HR1 domain in spike protein
Cellular & Molecular Immunology, 2020 Very recently, a novel coronavirus, 2019-nCoV, emerged in Wuhan, China and then quickly spread worldwide, resulting in >17,388 confirmed cases and 361 deaths as of 3 February 2020, thus calling for the development of safe and effective therapeutics and ...
Shuai Xia +10 more
semanticscholar +1 more source
Expression in Escherichia coli of a cloned DNA sequence encoding the pre-S2 region of hepatitis B virus [PDF]
, 1985 A DNA sequence encoding the entire pre-S2 region (amino acids 120-174; serotype ayw) of human hepatitis B virus envelope protein has been inserted into the lacZ gene of the plasmid pSKS105 yielding a recombinant, pWS3.
Acs, George +7 more
core +1 more source
Targeted delivery of autoantigen to dendritic cells prevents development of spontaneous uveitis
Frontiers in Immunology, 2023 Restoration of immunological tolerance to self antigens has been a major drive in understanding the mechanisms of, and developing new treatments for, autoimmune and autoinflammatory disease.
Izabela P. Klaska +10 more
doaj +1 more source
Journal of Cell Biology, 2012 Proximity-dependent biotin identification (BioID) is a new approach making use of biotin ligase fusion proteins for the identification of both interacting and neighboring proteins in their native cellular environment.
K. Roux, D. Kim, M. Raida, B. Burke
semanticscholar +1 more source
ATP-independent Control of Vac8 Palmitoylation by a SNARE Subcomplex on Yeast Vacuoles [PDF]
, 2005 Yeast vacuole fusion requires palmitoylated Vac8. We previously showed that Vac8 acylation occurs early in the fusion reaction, is blocked by antibodies against Sec18 (yeast N-ethylmaleimide-sensitive fusion protein (NSF)), and is mediated by the R-SNARE
Cristodero, Marina +5 more
core +1 more source
Engineering a New IFN-ApoA-I Fusion Protein with Low Toxicity and Prolonged Action
Molecules, 2023 Recombinant human interferon alpha-2b (rIFN) is widely used in antiviral and anticancer immunotherapy. However, the high efficiency of interferon therapy is accompanied by a number of side effects; this problem requires the design of a new class of ...
Svetlana Miroshnichenko +4 more
doaj +1 more source
Protein-Protein Fusion Catalyzed by Sortase A
PLoS ONE, 2011 Chimeric proteins boast widespread use in areas ranging from cell biology to drug delivery. Post-translational protein fusion using the bacterial transpeptidase sortase A provides an attractive alternative when traditional gene fusion fails. We describe use of this enzyme for in vitro protein ligation and report the successful fusion of 10 pairs of ...
Ranganath Parthasarathy +3 more
openaire +5 more sources