Results 151 to 160 of about 2,428,275 (198)

LIN28A-Dependent Kinome and Phosphoproteome Reprogramming Promotes Imatinib Resistance. [PDF]

Mol Cell Proteomics
Hovey OFJ, Frederick MI, Quach QM, Kakadia JH, Wu A, Yang K, Wu T, Ruan X, Kaneko T, Voss C, Heinemann IU, Li SSC.   +11 more
europepmc   +1 more source

Assessment of Tfh Cells and Related Molecules in CML-CP Patients With Different Molecular Responses. [PDF]

Int J Lab Hematol
Wang Y, Geng S, Chen X, Huang L, Huang X, Luo Q, Zeng L, Wu P, Zhang Y, Liu K, Du X, Weng J, Lai P.   +12 more
europepmc   +1 more source

Streptomyces koyangensis L-asparaginase: computational prediction of dual-mechanism BCL-2 interaction in acute lymphoblastic leukemia. [PDF]

Sci Rep
Solanki G, Prajapati C, Gadhvi R, Kamble L, Sharma MC, Hajare ST.   +5 more
europepmc   +1 more source

Chronic Myeloid Leukemia: Historical Perspective, Pathophysiology, and Treatment Advances.

Acta Haematol
Tungjitviboonkun S, Daran L, Unsuwan S.
europepmc   +1 more source

Dual Proteasome and Histone Deacetylase Inhibition Overcomes Tyrosine Kinase Inhibitor Resistance in Breakpoint Cluster Region: Abelson 1-Driven Leukaemia Cell Lines. [PDF]

J Cell Mol Med
Okabe S, Yoshizawa S, Arai Y, Gotoh A, Akahane D.   +4 more
europepmc   +1 more source

Inhibition of Pellino-1 reverts the progression and tyrosine kinase inhibitor resistance in chronic myeloid leukemia. [PDF]

Cell Death Dis
Zhou Q, Xu G, Li Z, Xu Y, Guan J, Li Z, Li M, Zu T, Li Y, Lu C, Ji C, Zhao B.   +11 more
europepmc   +1 more source

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An immunological method for the detection of BCR-ABL fusion protein and monitoring its activation

Leukemia Research, 2008
We have developed a simplified sandwich immunoassay to measure free circulating total and phosphorylated fusion BCR-ABL protein in patients with the t(9;22)(q34;q11) chromosomal translocation. The assay is based on immunoprecipitating BCR-ABL protein using beads coated with anti-BCR antibody and detecting the fusion protein with anti-ABL antibody and ...
Kapil Bhalla, Maher Albitar, Oliver Ottmann   +2 more
exaly   +3 more sources

Nuclear topography and expression of the BCR/ABL fusion gene and its protein level influenced by cell differentiation and RNA interference

Leukemia Research, 2005
Nuclear topography, expression of the BCR/ABL fusion gene and its protein level/cellular pattern were studied in CML cell line K562 stimulated to differentiation, apoptosis and influenced by ABL-RNA interference (ABL-RNAi). Phorbol ester-induced maturation of K562 cells was accompanied by repositioning of down-regulated BCR/ABL genes closer to the ...
Eva Bártová, Stanislav Kozubek, Jiřı́ Pachernı́K   +2 more
exaly   +3 more sources

Characterization of a Monoclonal Antibody Specific for Novel Bcr/Abl Out-of-Frame Fusion Proteins

Hybridoma, 2011
The new tumor-specific antigens Bcr/Abl-OOF, identified in Philadelphia chromosome (Ph)-positive leukemia cells, are derived from an alternative splicing event involving BCR exons 1, 13, or 14 and ABL exons 4 and 5. The COOH-terminus of these transcription products contain an amino acid portion derived from an out-of-frame (OOF) reading of the ABL gene;
Casnici C, VOLPE, Gisella, Crotta K, PANUZZO, Cristina, Lattuada D, Cabras CA, Longhi R, SAGLIO, Giuseppe, Marelli O.   +8 more
openaire   +5 more sources