Results 111 to 120 of about 41,327 (291)

Gasdermin‐Mediated Pyroptosis: Novel Strategies Against Colorectal Cancer

Cancer Science, EarlyView.
Pyroptosis is a double‐edged sword in colorectal cancer (CRC): chronic low‐grade pyroptosis promotes tumor progression, whereas acute induction of pyroptosis in cancer cells triggers antitumor immunity and enhances therapeutic response. Targeting gasdermin‐mediated pyroptosis represents a promising strategy for CRC treatment.
Kaibo Guo, Yuqian Feng, Jiamin Lu, Nuerbiye Abudurexiti, Xinlei Zhou, Mengfan Wei, Song Zheng   +6 more
wiley   +1 more source

Does Fusobacterium in Colorectal Cancer Sites Originate From the Oral Cavity? A Pilot Study

Clinical and Experimental Dental Research
Objectives Fusobacterium can contribute to oral diseases, but also pose as a systemic risk factor. This genus, and especially F. nucleatum, can be found in colorectal cancer (CRC) tissue and is involved in multiple aspects of this type of cancer ...
Niels Plomp, Kristina Bertl, Marie‐Louise Lydrup, Klas Sjöberg, Hermie J. M. Harmsen, Andreas Stavropoulos   +5 more
doaj   +1 more source

Fusobacterium and colorectal carcinogenesis [PDF]

Carcinogenesis, 2017
Deniz Can Güven, Omer Dizdar
openaire   +2 more sources

A Comparison of Endodontic Microbiomes Associated With Symptomatic and Asymptomatic Apical Periodontitis by Next‐Generation Sequencing

International Endodontic Journal, EarlyView.
ABSTRACT Aim This cross‐sectional study aimed to compare the endodontic microbiome assessed from root canals of teeth associated with either symptomatic or asymptomatic apical periodontitis and analysed by 16S rDNA gene sequencing. Methodology 60 teeth presenting clinical and radiographic signs of symptomatic or asymptomatic apical periodontitis (n ...
David Donnermeyer, Edgar Schäfer, Daniel Hagenfeld, Benjamin Ehmke, Karola Prior, Dag Harmsen, Madgalena Ibing, Sebastian Bürklein, Thomas Gerhard Wolf, Johannes Matern   +9 more
wiley   +1 more source

Epidemiology and Clinical Outcomes of Fusobacterium Infections: A Six-Year Retrospective Study

Medicina
Background and Objectives: Anaerobic bacteria like Fusobacterium can lead to severe and life-threatening infections. The inherent complexities in the isolation of these bacteria may result in diagnostic and therapeutic delays, thereby escalating both ...
Akram Khan, Hamza Alzghoul, Abdul Ahad Khan, Gopal Allada, Juliann M. Gronquist, Jonathan Pak, Srini Mukundan, Bishoy Zakhary, Raghav Wusirika, Nehan Sher, Raju Reddy   +10 more
doaj   +1 more source

Fusobacterium nucleatum亜種分離株におけるバイオフィルム形成能力の比較解析 [PDF]

大阪歯科大学Osaka Dental University博士（歯学）The oral commensal Fusobacterium nucleatum (Fn) is critical in biofilm development. Although differences in biofilm formation among subspecies have been reported, detailed analyses of the isolates are scarce.
カク, ホンウィ, 郝, 虹煒, Hao, Hongwei   +2 more
core   +1 more source

Systemic Antibiotics in the Surgical Treatment of Peri‐Implantitis: Impact on the Salivary Microbiome

Journal of Clinical Periodontology, EarlyView.
ABSTRACT Aim To exploratorily compare the shifts in the salivary microbiome composition after administration of two combined systemic antibiotic regimens used in the surgical treatment of peri‐implantitis. Materials and Methods A subset of 27 patients treated surgically for peri‐implantitis with an adjunctive 7‐day course of systemic antibiotics were ...
Caroline Riben Grundström, Bodil Lund, Nagihan Bostanci, Angelika Silbereisen, Alexandra Pennhag, Ina Schuppe Koistinen, Yinghua Zha, Anastasios Damdimopoulos, Georgios N. Belibasakis, Margareta Hultin   +9 more
wiley   +1 more source

Early‐Onset Oral Squamous Cell Carcinoma: Emerging Biological Insights, Risk Factors and Clinical Implications

Journal of Oral Pathology &Medicine, EarlyView.
ABSTRACT Background Early‐onset oral squamous cell carcinoma (EO‐OSCC), commonly defined as occurring in individuals under 50 years of age, is increasingly recognized as a potentially distinct clinical subset with differences in exposure patterns and tumor biology compared with conventional oral squamous cell carcinoma (OSCC).
Gennaro Musella, Cristina D'Antonio, Federica Canfora, Michele D. Mignogna, Valentino Vellone, Vito Carlo Alberto Caponio, Amerigo Giudice, Alessandro Villa, Daniela Adamo   +8 more
wiley   +1 more source

Fusobacterium nucleatum 由来の細胞外膜小胞が神経分化に及ぼす影響 [PDF]

大阪歯科大学Osaka Dental University博士（歯学）The periodontopathogenic bacterium Fusobacterium nucleatum (F. nucleatum) has attracted significant attention because of its association with many systemic diseases.
水谷, 翔, Mizutani, Sho, ミズタニ, ショウ   +2 more
core   +1 more source

Genetic Susceptibility to Periodontitis

Journal of Periodontal Research, EarlyView.
Aim: The aim of this narrative review was to identify genes carrying risk alleles associated with an increased risk of periodontitis and to place them in a biological context. Methods: The literature was reviewed based on predefined criteria. Results: The identified genes largely fall into functions linking immune response with tissue repair. The genes
Gesa M. Richter, Arne S. Schaefer
wiley   +1 more source