Periodontitis and Diabetes: Mechanistic Evidence of a Circular Relationship
This narrative review aimed to explore the underlying mechanisms that connect periodontitis to diabetes (and vice versa) and that influence disease susceptibility, progression and response to treatment. ABSTRACT The circular relationship between periodontitis and diabetes mellitus is one of the most established oral‐systemic links.
Philip M. Preshaw +4 more
wiley +1 more source
Periodontitis and Rheumatoid Arthritis—Mechanistic Evidence
Periodontitis and rheumatoid arthritis are linked via the two‐hit model whereby early periodontal inflammation can lead to autoantibody production capable of interacting with inflamed synovial tissues. Subsequent systemic inflammation can exacerbate the periodontal inflammatory response and bacterial dysbiosis leading to further autoantibody production
Mark Bartold +2 more
wiley +1 more source
Periodontitis and Adverse Pregnancy Outcomes: Mechanistic Evidence
This narrative review aims to describe mechanisms linking periodontal diseases in pregnancy with adverse pregnancy outcomes. ABSTRACT Periodontal diseases, including both gingivitis and periodontitis, occur commonly among pregnant individuals. Both gingivitis and periodontitis are associated with adverse pregnancy outcomes (APOs) such as early ...
Gregory C. Valentine +4 more
wiley +1 more source
Natural‐inspired nano‐textured implant surfaces can be functionalised to modulate macrophage polarisation and local immune responses. This bioactive control promotes improved tissue integration and healing outcomes. ABSTRACT Dental implants rely on a stable and functional interface between the implant surface, surrounding tissues, and the oral ...
Roberto S. Pessoa +9 more
wiley +1 more source
Intratumoral Fusobacterium species and survival in resectable colorectal cancer: a multicenter cohort study. [PDF]
Serna G +41 more
europepmc +1 more source
Saliva Liquid Biopsy for Detection of Oral and Systemic Diseases
This Review summarizes and discusses the biological foundations and major classes of salivary biomarkers, outlines collection methods and analytical protocols for saliva‐based liquid biopsy, and technological convergences driven by multi‐omics approaches, artificial intelligence, and point‐of‐care devices in the application of oral and systemic ...
Irene Choi +10 more
wiley +1 more source
First Draft genome sequence of strain MF0224, representing an unclassified <i>Fusobacterium</i>-related lineage isolated from coastal sediments of Puducherry, India. [PDF]
Prathaban M +7 more
europepmc +1 more source
The Dual Face of Fusobacterium nucleatum in Cancer: Foe, Friend or Both?
Fusobacterium nucleatum has established interactions with cancers in humans. However, contrary to a traditional view that these interactions are uniformly pro‐tumoural, recent evidence suggests a more nuanced role, where contact‐dependent and contact‐independent mechanisms may support either tumour progression or restriction depending on tumour site ...
Anjali Chander +3 more
wiley +1 more source
HumanFilt: a multi-reference host depletion pipeline improves <i>Fusobacterium</i> detection accuracy in tumor WGS data sets. [PDF]
Frolova M +10 more
europepmc +1 more source
Emerging evidence suggests that periodontal health is not simply the absence of disease, but the result of a dynamic interaction between biological resilience, healthy lifestyles, adaptive coping mechanisms, and supportive environments. This results in a strong sense of coherence, which is not only a psychological state but also a biological state ...
Bruno G. Loos +4 more
wiley +1 more source

