Results 101 to 110 of about 22,381 (249)

Periodontitis and Diabetes: Mechanistic Evidence of a Circular Relationship

open access: yesJournal of Periodontal Research, EarlyView.
This narrative review aimed to explore the underlying mechanisms that connect periodontitis to diabetes (and vice versa) and that influence disease susceptibility, progression and response to treatment. ABSTRACT The circular relationship between periodontitis and diabetes mellitus is one of the most established oral‐systemic links.
Philip M. Preshaw   +4 more
wiley   +1 more source

Periodontitis and Rheumatoid Arthritis—Mechanistic Evidence

open access: yesJournal of Periodontal Research, EarlyView.
Periodontitis and rheumatoid arthritis are linked via the two‐hit model whereby early periodontal inflammation can lead to autoantibody production capable of interacting with inflamed synovial tissues. Subsequent systemic inflammation can exacerbate the periodontal inflammatory response and bacterial dysbiosis leading to further autoantibody production
Mark Bartold   +2 more
wiley   +1 more source

Periodontitis and Adverse Pregnancy Outcomes: Mechanistic Evidence

open access: yesJournal of Periodontal Research, EarlyView.
This narrative review aims to describe mechanisms linking periodontal diseases in pregnancy with adverse pregnancy outcomes. ABSTRACT Periodontal diseases, including both gingivitis and periodontitis, occur commonly among pregnant individuals. Both gingivitis and periodontitis are associated with adverse pregnancy outcomes (APOs) such as early ...
Gregory C. Valentine   +4 more
wiley   +1 more source

Meningitis caused by Fusobacterium nucleatum complicated with cavernous sinus thrombosis: A case report

open access: yesInternational Journal of Infectious Diseases
Introduction: Bacterial meningitis caused by anaerobes, particularly Fusobacterium, is highly unusual. Fusobacterium necrophorum is the most significant pathogen; however, information regarding F. nucleatum meningitis is extremely scarce.
Michael Ariza-Varón   +4 more
doaj   +1 more source

Next Generation Smart Implant Surfaces: Engineering Multifunctional Antimicrobial, Immunomodulatory and Regenerative Interfaces

open access: yesJournal of Periodontal Research, EarlyView.
Natural‐inspired nano‐textured implant surfaces can be functionalised to modulate macrophage polarisation and local immune responses. This bioactive control promotes improved tissue integration and healing outcomes. ABSTRACT Dental implants rely on a stable and functional interface between the implant surface, surrounding tissues, and the oral ...
Roberto S. Pessoa   +9 more
wiley   +1 more source

The potential of antimicrobial peptides to treat oral infections and cancer

open access: yesFrontiers in Medicine
Oral cancer represents a significant cause of mortality and morbidity, especially when discovered late. Microbial infections, particularly those caused by Porphyromonas gingivalis and Fusobacterium nucleatum, play a crucial role in cancer development and
Ana Emilia Carvalho de Paula   +2 more
doaj   +1 more source

Association of Fusobacterium nucleatum infection with colorectal cancer in Kazakhstani patients

open access: yesFrontiers in Oncology
ObjectivesFusobacterium nucleatum is a gram-negative anaerobic bacillus associated with colorectal cancer (CRC). We aimed to determine the abundance of F. nucleatum and other CRC-associated bacteria using quantitative real-time polymerase chain reaction (qPCR) analysis to detect the possible correlations between tumor and normal tissues and the ...
Gulmira Kulmambetova   +9 more
openaire   +3 more sources

Saliva Liquid Biopsy for Detection of Oral and Systemic Diseases

open access: yesJournal of Periodontal Research, EarlyView.
This Review summarizes and discusses the biological foundations and major classes of salivary biomarkers, outlines collection methods and analytical protocols for saliva‐based liquid biopsy, and technological convergences driven by multi‐omics approaches, artificial intelligence, and point‐of‐care devices in the application of oral and systemic ...
Irene Choi   +10 more
wiley   +1 more source

The Dual Face of Fusobacterium nucleatum in Cancer: Foe, Friend or Both?

open access: yesJournal of Periodontal Research, EarlyView.
Fusobacterium nucleatum has established interactions with cancers in humans. However, contrary to a traditional view that these interactions are uniformly pro‐tumoural, recent evidence suggests a more nuanced role, where contact‐dependent and contact‐independent mechanisms may support either tumour progression or restriction depending on tumour site ...
Anjali Chander   +3 more
wiley   +1 more source

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