Results 91 to 100 of about 22,082 (267)
Gasdermin‐Mediated Pyroptosis: Novel Strategies Against Colorectal Cancer
Cancer Science, EarlyView.Pyroptosis is a double‐edged sword in colorectal cancer (CRC): chronic low‐grade pyroptosis promotes tumor progression, whereas acute induction of pyroptosis in cancer cells triggers antitumor immunity and enhances therapeutic response. Targeting gasdermin‐mediated pyroptosis represents a promising strategy for CRC treatment.
Kaibo Guo +6 more
wiley +1 more source
Síndrome de Lemierre: relato de caso Lemierre syndrome: case report
Jornal Vascular Brasileiro, 2010 A síndrome de Lemierre é uma doença rara, mais comum em jovens, causada frequentemente pelo Fusobacterium necrophorum. Inicia-se com faringite e propaga-se até a veia jugular interna, promovendo uma fonte de bacteremia contínua e êmbolos sépticos ...
Gustavo Ioshio Handa +7 more
doaj
Lemierre's Syndrome Case Secondary to Otitis Media
Turkish Archives of Otorhinolaryngology, 2015 Lemierre’s syndrome is a rare but fatal thrombophlebitis of the internal jugular vein (IJV). It usually follows acute oropharyngeal infections in healthy, young adults. Fusobacterium necrophorum is the most common bacteria that causes Lemierre’s syndrome,
Göksel Turhal +4 more
doaj +1 more source
Case Reports in Hematology, 2016 Hemophagocytic lymphohistiocytosis (HLH) is a rare syndrome characterized by excessive activation of the immune system. Bacterial infections are very rare precipitants of this disease. A 19-year-old gentleman presented with headache, fatigue, and malaise.
Ghulam Rehman Mohyuddin, Heather J. Male
doaj +1 more source
Understanding the role of different strain types of Fusobacterium necrophorum: biofilms, glycans and metabolic pathways [PDF]
, 2019 Fusobacterium necrophorum an obligate Gram-negative anaerobe has been implicated in the cause of persistent severe throat infections and the systemic life-threatening Lemierre’s syndrome; a potentially fatal periodontal disease, which results in abscess ...
Brimah, K.
core +1 more source
International Endodontic Journal, EarlyView.ABSTRACT Aim This cross‐sectional study aimed to compare the endodontic microbiome assessed from root canals of teeth associated with either symptomatic or asymptomatic apical periodontitis and analysed by 16S rDNA gene sequencing. Methodology 60 teeth presenting clinical and radiographic signs of symptomatic or asymptomatic apical periodontitis (n ...
David Donnermeyer +9 more
wiley +1 more source
A Cough May be Just the Tip of the Iceberg
Graduate Medical Education Research Journal, 2019 Mentor: Michael Smith Program: Internal Medicine Pyogenic liver abscesses (PLAs) can be diagnostically challenging, as they may present with non-specific symptoms and are less frequently encountered than other types of infections. PLAs caused by atypical
Ian Cormier, Neil Bhogal, Michael Smith
doaj +1 more source
Mechanistic studies of Fusobacterium genetic and defense systems
, 2020 Fusobacterium are Gram-negative anaerobic bacteria that colonize a variety of eukaryotes including cattle and humans. In humans, Fusobacterium coordinates the central architecture of the oral biofilm by expressing an abundance of outer membrane adhesins ...
Umana Torres, Ariana
core
, 2015 The purpose of this investigation was to describe the clinical spectrum of invasive Fusobacterium necrophorum infections and Lemièrre's syndrome, to examine the role of underlying thrombophilia and concomitant mononucleosis in Lemièrre's syndrome, and to
Holm, Karin +2 more
core +2 more sources
International Endodontic Journal, EarlyView.ABSTRACT Aim To characterize the intracanal microbiota and identify key microbial taxa and functional pathways associated with regenerative endodontic treatment (RET) outcomes. Methodology In this observational cohort study, 196 samples were collected at five time points from external tooth surfaces (T1, T4) and root canals (T2, T3, T5).
Leimarembi Devi Naorem +7 more
wiley +1 more source