Results 1 to 10 of about 33,412 (306)

Fusobacterium nucleatum in tumors: from tumorigenesis to tumor metastasis and tumor resistance [PDF]

Cancer Biology & Therapy
Fusobacterium nucleatum, an anaerobic Gram-negative bacterium primarily residing in the oral cavity, has garnered significant attention for its emerging role in cancer progression and prognosis.
Chun Ye, Xiao Liu, Zilun Liu, Chuxuan Pan, Xiaowei Zhang, Zhanyi Zhao, Haitao Sun   +6 more
doaj   +3 more sources

Fusobacterium nucleatum and cancer [PDF]

Periodontology 2000, 2022
Accumulating evidence demonstrates that the oral pathobiont Fusobacterium nucleatum is involved in the progression of an increasing number of tumors types. Thus far, the mechanisms underlying tumor exacerbation by F.
Tamar Alon-Maimon, O. Mandelboim, G. Bachrach   +2 more
semanticscholar   +3 more sources

Fusobacterium nucleatum reduces METTL3-mediated m6A modification and contributes to colorectal cancer metastasis

Nature Communications, 2022
Fusobacterium nucleatum contributes to host epitranscriptomic modifications and colorectal cancer (CRC) development. Here, the authors show that Fusobacterium nucleatum reduces global m6A modifications to promote CRC metastasis through a YAP/FOXD3/METTL3/
Shujie Chen,, Lu Zhang, Mengjie Li, Ying Zhang, Meng Sun, Lingfang Wang, Jiebo Lin, Yun Cui, Qian Chen, Chenqi Jin, Xiang Li, Boya Wang, Hao Chen, Tianhua Zhou, Liangjing Wang, Chih-Hung Hsu, Wei Zhuo   +16 more
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Detection of fusobacterium nucleatum and fadA adhesin gene in patients with orthodontic gingivitis and non-orthodontic periodontal inflammation. [PDF]

PLoS ONE, 2014
Fusobacterium nucleatum is one of the most abundant gram-negative bacilli colonizing the subgingival plaque and closely associated with periodontal disease. However it is unclear whether F. nucleatum is involved in gingival inflammation under orthodontic
Ping Liu, Yi Liu, Jianning Wang, Yang Guo, Yujie Zhang, Shuiqing Xiao   +5 more
doaj   +3 more sources

Fusobacterium nucleatum upregulates the immune inhibitory receptor PD-L1 in colorectal cancer cells via the activation of ALPK1

Gut Microbes
Fusobacterium nucleatum is a Gram-negative oncobacterium that is associated with colorectal cancer. The molecular mechanisms utilized by F. nucleatum to promote colorectal tumor development have largely focused on adhesin-mediated binding to the tumor ...
Coco Duizer, Moniek Salomons, Merel van Gogh, Sanne Gräve, Freke A. Schaafsma, Maaike J. Stok, Merel Sijbranda, Raghuvandhanan Kumarasamy Sivasamy, Rob J. L. Willems, Marcel R. de Zoete   +9 more
doaj   +2 more sources

Fusobacterium nucleatum — symbiont, opportunist and oncobacterium [PDF]

Nature Reviews Microbiology, 2018
Fusobacterium nucleatum has long been found to cause opportunistic infections and has recently been implicated in colorectal cancer; however, it is a common member of the oral microbiota and can have a symbiotic relationship with its hosts. To address this dissonance, we explore the diversity and niches of fusobacteria and reconsider historic ...
C. Brennan, W. Garrett
semanticscholar   +3 more sources

Breast cancer colonization by Fusobacterium nucleatum accelerates tumor growth and metastatic progression

Nature Communications, 2020
High levels of Fusobacterium nucleatum have been associated with poor overall survival in patients with colorectal and esophageal cancer. Here, the authors show that F.
Lishay Parhi, Tamar Alon-Maimon, Asaf Sol, Deborah Nejman, Amjad Shhadeh, Tanya Fainsod-Levi, Olga Yajuk, Batya Isaacson, Jawad Abed, Naseem Maalouf, Aviram Nissan, Judith Sandbank, Einav Yehuda-Shnaidman, Falk Ponath, Jörg Vogel, Ofer Mandelboim, Zvi Granot, Ravid Straussman, Gilad Bachrach   +18 more
doaj   +2 more sources

COVID-19–Associated Fusobacterium nucleatum Bacteremia, Belgium [PDF]

Emerging Infectious Diseases, 2021
We report 4 cases of Fusobacterium nucleatum bacteremia associated with coronavirus disease (COVID-19). Three cases occurred concomitantly with COVID-19 diagnosis; 1 occurred on day 15 of intensive care. None of the patients had known risk factors for F.
Louis Wolff, Delphine Martiny, Véronique Yvette Miendje Deyi, Evelyne Maillart, Philippe Clevenbergh, Nicolas Dauby   +5 more
doaj   +4 more sources

Investigation of the relationship between Fusobacterium nucleatum presence and inflammatory mediator expression in Kazakhstani patients with colorectal cancer [PDF]

Frontiers in Microbiology
ObjectivesFusobacterium nucleatum has been recognized as a critical microorganism contributing to the development and progression of colorectal cancer (CRC). However, the role of F.
Gulmira Kulmambetova, Botakoz Kurentay, Alua Gusmaulemova, Dina Bayanbek, Meiram Mamlin, Saule Khamzina, Sanzhar Shalekenov, Arman Kozhakhmetov   +7 more
doaj   +2 more sources

Progress in Fusobacterium nucleatum

Di-san junyi daxue xuebao, 2019
Fusobacterium nucleatum (F. nucleatum) is one of the resident members in oral microflora, and has a symbiotic relationship with the host. F. nucleatum can cause a variety of opportunistic infections, and many recent studies have linked it to the ...
MAO Xuhu, TONG Yanan
doaj   +2 more sources