Results 31 to 40 of about 17,845 (237)

Tumour microbiomes and Fusobacterium genomics in Vietnamese colorectal cancer patients

npj Biofilms and Microbiomes, 2022
Perturbations in the gut microbiome have been associated with colorectal cancer (CRC), with the colonic overabundance of Fusobacterium nucleatum shown as the most consistent marker.
Hoang N. H. Tran, Trang Nguyen Hoang Thu, Phu Huu Nguyen, Chi Nguyen Vo, Khanh Van Doan, Chau Nguyen Ngoc Minh, Ngoc Tuan Nguyen, Van Ngoc Duc Ta, Khuong An Vu, Thanh Danh Hua, To Nguyen Thi Nguyen, Tan Trinh Van, Trung Pham Duc, Ba Lap Duong, Phuc Minh Nguyen, Vinh Chuc Hoang, Duy Thanh Pham, Guy E. Thwaites, Lindsay J. Hall, Daniel J. Slade, Stephen Baker, Vinh Hung Tran, Hao Chung The   +22 more
doaj   +1 more source

FadA promotes DNA damage and progression of Fusobacterium nucleatum-induced colorectal cancer through up-regulation of chk2

Journal of Experimental & Clinical Cancer Research, 2020
Background Globally, colorectal cancer (CRC) affects more than 1 million people each year. In addition to non-modifiable and other environmental risk factors, Fusobacterium nucleatum infection has been linked to CRC recently.
Pin Guo, Zibin Tian, Xinjuan Kong, Lin Yang, Xinzhi Shan, Bingzi Dong, Xueli Ding, Xue Jing, Chen Jiang, Na Jiang, Yanan Yu   +10 more
doaj   +1 more source

Antibacterial effect of a gingival patch containing nano-emulsion of red dragon fruit peel extract on Porphyromonas gingivalis, Aggregatibacter actinomycetemcomitans, and Fusobacterium nucleatum assessed in vitro

Journal of Oral Biology and Craniofacial Research, 2023
Background: The most common bacteria causing periodontitis were Porphyromonas gingivalis, Fusobacterium nucleatum and Aggregatibacter actinomycetemcomitans.
Indeswati Diyatri, Wisnu Setyari Juliastuti, Rini Devijanti Ridwan, Ghinalya Chalbi Ananda, Fuad Adhi Waskita, Nita Vania Juliana, Shafa Putri Khansa, Reinaya Tifa Pratiwi, Cindy Ramadhan Putri   +8 more
doaj   +1 more source

Primary meningitis due to Fusobacterium nucleatum successfully treated with ceftriaxone in a healthy adult male

IDCases, 2019
Fusobacterium nucleatum is a rod-shaped gram-negative obligate anaerobe; this organism, and other anaerobes, are usually not a part of the culture performed for a cerebrospinal fluid (CSF) sample. To date, four cases of Fusobacterium meningitis in adults
Trager Hintze, Michelle Steed, Eric Sievers, John T. Bagwell, Nicola Selfa   +4 more
doaj   +1 more source

Fusobacterium Species and Subspecies Differentially Affect the Composition and Architecture of Supra- and Subgingival Biofilms Models

Frontiers in Microbiology, 2019
Fusobacteria are common obligately anaerobic Gram-negative bacteria of the oral cavity that may act as a bridge between early and late colonizing bacteria in dental plaque and have a role in oral and extra-oral infections.
Thomas Thurnheer, Lamprini Karygianni, Manuela Flury, Georgios N. Belibasakis   +3 more
doaj   +1 more source

Fusobacterium nucleatum subsp. fusiforme subsp. nov. and Fusobacterium nucleatum subsp. animalis subsp. nov. as Additional Subspecies within Fusobacterium nucleatum [PDF]

International Journal of Systematic Bacteriology, 1992
Using a variety of physiological, biochemical, and molecular systematic analyses, we have shown previously that there are four groups within the species Fusobacterium nucleatum. Two of these groups of strains correspond to the recently proposed taxa F. nucleatum subsp. nucleatum and F. nucleatum subsp. polymorphum.
S E, Gharbia, H N, Shah
openaire   +2 more sources

Comparative Genome Analysis ofFusobacterium nucleatum [PDF]

Genome Biology and Evolution, 2016
Fusobacterium nucleatum is considered to be a key oral bacterium in recruiting periodontal pathogens into subgingival dental plaque. Currently F. nucleatum can be subdivided into five subspecies. Our previous genome analysis of F. nucleatum W1481 (referred to hereafter as W1481), isolated from an 8-mm periodontal pocket in a patient with chronic ...
Ang, Mia Yang, Dutta, Avirup, Wee, Wei Yee, Dymock, David, Paterson, Ian C, Choo, Siew Woh   +5 more
openaire   +4 more sources

Increasing Fusobacterium infections with Fusobacterium varium, an emerging pathogen

PLoS ONE, 2022
Infections caused by Fusobacterium species are rare; however serious infections with complications or mortality may occur occasionally. We conducted a retrospective study to investigate the clinical features of patients with Fusobacterium infections and ...
Se Ju Lee, Yae Jee Baek, Jin Nam Kim, Ki Hyun Lee, Eun Hwa Lee, Joon Sup Yeom, Jun Yong Choi, Nam Su Ku, Jin Young Ahn, Jung Ho Kim, Su Jin Jeong   +10 more
doaj   +2 more sources

Comparative genomic analysis of Fusobacterium nucleatum reveals high intra-species diversity and cgmlst marker construction

Gut Pathogens, 2023
Background Fusobacterium nucleatum is a one of the most important anaerobic opportunistic pathogens in the oral and intestinal tracts of human and animals.
Qianhui Zhu, Arslan Dovletgeldiyev, Chen Shen, Kexin Li, Songnian Hu, Zilong He   +5 more
doaj   +1 more source

Fusobacterium nucleatum Secretes Outer Membrane Vesicles and Promotes Intestinal Inflammation

mBio, 2021
Multiple studies have implicated microbes in the development of inflammation, but the mechanisms remain unknown. Bacteria in the genus Fusobacterium have been identified in the intestinal mucosa of patients with digestive diseases; thus, we hypothesized ...
Melinda A. Engevik, Heather A. Danhof, Wenly Ruan, Amy C. Engevik, Alexandra L. Chang-Graham, Kristen A. Engevik, Zhongcheng Shi, Yanling Zhao, Colleen K. Brand, Evan S. Krystofiak, Susan Venable, Xinli Liu, Kendal D. Hirschi, Joseph M. Hyser, Jennifer K. Spinler, Robert A. Britton, James Versalovic   +16 more
doaj   +1 more source