Results 51 to 60 of about 17,845 (237)

Fusobacterium lineage profiling facilitates the clarification of the associations between non-nucleatum Fusobacterium and colorectal cancer

npj Biofilms and Microbiomes
Non-nucleatum Fusobacterium may play a nonnegligible role in colorectal cancer (CRC) and certain Fusobacterium lineages (namely, L1 and L5) have shown specific associations with CRC. We aim to clarify the complex connections between Fusobacterium and CRC.
Yuli Wu, Guo Ji, Dongyan Han, Youhua Zhang, Xingchen Zhu, Hao Li, Man Li, Yaohui Gao, Ruting Xie, Min Xu, Ling Lu, Zixin Deng, Qing Wei, Huanlong Qin, Dexi Bi   +14 more
doaj   +1 more source

Mobile Genetic Elements of Fusobacterium nucleatum

Plasmid, 1995
The gram-negative anaerobic bacterium, Fusobacterium nucleatum, is a predominant member of the human oral flora. As a major component of subgingival plaque, this bacterium has a significant impact on the ecology of the oral cavity due to its ability to adhere to many different microbial species.
T L, McKay, J, Ko, Y, Bilalis, J M, DiRienzo   +3 more
openaire   +2 more sources

Mining Oral Probiotics Based on Their Pathogen Inhibition and Deodorization Roles

Food Bioengineering, EarlyView.
A promising oral probiotic strain Streptococcus salivarius MY‐6 stood out from 41 candidate lactic acid bacteria through the high‐throughput strategy based on its inhibitions of the growth and biofilm formation of the main oral pathogens Fusobacterium nucleatum and Porphyromonas gingivalis, as well as its elimination of oral malodor‐associated ...
Yaao Chen, Xiaofeng Xu, Yang Long, Deyi Yin, Haohao Sheng, Lei Du, Minxi Wan, Li Zhao, Jingli Xie   +8 more
wiley   +1 more source

A Modified Method Incorporating Multiplex PCR Reveals Fusobacterium Prevalence in Southern Chinese Population and Its Correlations in Cancers

Microbial Biotechnology
Fusobacterium, a gram‐negative anaerobic bacillus in mouth, gastrointestinal tract and elsewhere, has long been considered as opportunistic pathogen. Increasing evidence indicate the association of Fusobacterium with human diseases, especially cancer ...
Tingting Shen, Jiarui Liang, Xuyu Li, Xiaoxie Xu, Liqiong Li, Yinjuan Xu, Shanshui Zeng, Bingyu Li, Hui Li, Mengyao Hu, Lang Zhou, Siqi Yan, Ya Zhang, Ziwei Zhou, Huaaishi Liang, Shulei Chen, Zhikun Liang, Congrong Wang, Hongwei Zhou, Dongxin Zhang   +19 more
doaj   +1 more source

Fusobacterium nucleatum promotes the development of acute liver failure by inhibiting the NAD+ salvage metabolic pathway

Gut Pathogens, 2022
Background Acute liver failure (ALF) patients are often accompanied by severe energy metabolism abnormalities and intestinal microecological imbalance. The intestinal mucosal barrier is severely damaged.
Pan Cao, Qian Chen, Chunxia Shi, Luwen Wang, Zuojiong Gong   +4 more
doaj   +1 more source

Fusobacterium Nucleatum Empyema: An Atypical Presentation

European Journal of Case Reports in Internal Medicine, 2020
A 40-year-old man presented to the emergency room and was evaluated in the internal medicine department for unexplained weight loss, asthenia, anorexia and night sweats over the previous 2 months. After a loculated pleural effusion was identified on thoracic computed tomography, purulent fluid was drained from the lung and Fusobacterium nucleatum was ...
Barrera-López, Lucía, Macía-Rodríguez, Cristina, Ferreiro-Fernández, Lucía, Díaz-Peromingo, José Antonio   +3 more
openaire   +4 more sources

A multilevel perspective on MSH6‐associated Lynch syndrome: Integrating molecular, biological, and clinical insights

International Journal of Cancer, EarlyView.
Abstract Lynch syndrome (LS) is the most common hereditary colorectal cancer syndrome, caused by a germline pathogenic variant in one of the mismatch repair (MMR) genes. Among these, MSH6‐associated LS represents a distinct subtype with unique molecular and clinical characteristics.
Salwa Ben Yahia, Anne‐Sophie van der Werf‐'t Lam, Madalina Cabuta, Maartje Nielsen, Noah C. Helderman   +4 more
wiley   +1 more source

Antagonistic interaction between two key endodontic pathogens Enterococcus faecalis and Fusobacterium nucleatum

Journal of Oral Microbiology, 2023
Background Endodontic infections are known to be caused by pathogenic bacteria. Numerous previous studies found that both Fusobacterium nucleatum and Enterococcus faecalis are associated with endodontic infections, with Fusobacterium nucleatum more ...
Doudou Xiang, Pu-Ting Dong, Lujia Cen, Batbileg Bor, Renate Lux, Wenyuan Shi, Qing Yu, Xuesong He, Tingxi Wu   +8 more
doaj   +1 more source

Unlocking insights: Validating a comprehensive model for predicting spontaneous preterm delivery and microbial invasion in women facing preterm labor

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective Preterm labor is a multifactorial syndrome with diverse etiologies such as infection, inflammation, uteroplacental dysfunction, stress, and immune dysregulation. Identifying women at high risk remains a challenge, and multivariate prediction models have been developed to enhance risk stratification.
Ester del Barco, Nerea Maiz, Clara Franco‐Jarava, Mireia Vargas, Silvia Arévalo, María A. Sánchez‐Durán, Carlota Rodó, Manel Mendoza, Marta Dalmau, Alba Casellas, Manuel Hernández‐González, Anna Suy, María Goya   +12 more
wiley   +1 more source

Advances in Immunological Combination Therapy for Colorectal Cancer

iMetaMed, EarlyView.
Review the progress of combined immunotherapy for colorectal cancer. ABSTRACT Immune checkpoint inhibitors (ICIs) have been utilized extensively and shown to be therapeutically beneficial in the treatment of solid tumors in recent years. Nonetheless, considerable heterogeneity in Colorectal cancer (CRC) requires careful consideration.
Jiayue Wu, Rongbo Wen, Tianshuai Zhang, Fuao Cao, Xiaoming Zhu, Liqiang Hao, Wei Zhang, Guanyu Yu   +7 more
wiley   +1 more source