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The Gram-negative, non-sporulating, obligately anaerobic species, Fusobacterium nucleatum, is rapidly gaining notoriety as a pathogen with a surprising number of associated diseases. Recently, we have found that F. nucleatum is a more common resident of the GI tract than originally thought, and thus, through several studies, we have attempted to ...
Emma, Allen-Vercoe +2 more
openaire +2 more sources
Emphysematous Cholecystitis Secondary to Fusobacterium nucleatum [PDF]
Fusobacterium nucleatum may be implicated in cases of emphysematous cholecystitis (EC) and carries a high mortality risk, especially in individuals with heart disease, renal insufficiency, and underlying malignancy. Fusobacterium infections are rarely detected in the setting of cholecystitis possibly due to the difficulty with properly culturing the ...
Kunadia, Anuj +4 more
openaire +2 more sources
Hemagglutinating activity of Fusobacterium nucleatum [PDF]
Gingival isolates of oral Fusobacterium nucleatum strains (gram-negative anaerobic fusiform bacilli) have shown the characteristic ability to hemagglutinate a variety of erythrocytes (RBC) of human and animal origin. Other members of the genus tested (F. necrophorus, F. varium, and F.
W A, Falkler, C E, Hawley
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Fusobacterium nucleatum and Colorectal Cancer
Fusobacterium nucleatum (F.n) is an oral anaerobic gram-negative bacillus that can colonize into the colon tissues through bloodstream infection. F.n have been found to be involved in both the occurrence and metastasis of colorectal cancer (CRC) through regulating immune response, virulence factor, oncogenic microRNAs, intestinal metabolites, DNA ...
Rongrong Li, Jilu Shen, Yuanhong Xu
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Fusobacterium nucleatum dissemination by neutrophils
Recent studies uncovered that Fusobacterium nucleatum (Fn), a common, opportunistic bacterium in the oral cavity, is associated with a growing number of systemic diseases, ranging from colon cancer to Alzheimer's disease. However, the pathological mechanisms responsible for this association are still poorly understood.
Felix Ellett +7 more
openaire +3 more sources
Background: The most common bacteria causing periodontitis were Porphyromonas gingivalis, Fusobacterium nucleatum and Aggregatibacter actinomycetemcomitans.
Indeswati Diyatri +8 more
doaj +1 more source
Background Globally, colorectal cancer (CRC) affects more than 1 million people each year. In addition to non-modifiable and other environmental risk factors, Fusobacterium nucleatum infection has been linked to CRC recently.
Pin Guo +10 more
doaj +1 more source
A new type of Na+-driven ATP synthase membrane rotor with a two-carboxylate ion-coupling motif [PDF]
: The anaerobic bacterium Fusobacterium nucleatum uses glutamate decarboxylation to generate a transmembrane gradient of Na+. Here, we demonstrate that this ion-motive force is directly coupled to ATP synthesis, via an F1Fo-ATP synthase with a novel Na ...
Leone, V +47 more
core +1 more source
Fusobacterium nucleatum subsp. fusiforme subsp. nov. and Fusobacterium nucleatum subsp. animalis subsp. nov. as Additional Subspecies within Fusobacterium nucleatum [PDF]
Using a variety of physiological, biochemical, and molecular systematic analyses, we have shown previously that there are four groups within the species Fusobacterium nucleatum. Two of these groups of strains correspond to the recently proposed taxa F. nucleatum subsp. nucleatum and F. nucleatum subsp. polymorphum.
S E, Gharbia, H N, Shah
openaire +2 more sources
Fusobacterium nucleatum and the Immune System in Colorectal Cancer
Purpose of Review To summarize the relationship between colorectal cancer (CRC), immunity, and the gut microbiome, focusing on the population of Fusobacterium, particularly Fusobacterium nucleatum, which may mediate CRC initiation and progression by ...
Farina, Floriana Maria +9 more
core +3 more sources

