Results 161 to 170 of about 33,412 (306)

The Role of Oxidative Stress in Periodontitis

Journal of Periodontal Research, EarlyView.
Oxidative stress is involved in multiple chemical reactions that take place in different intracellular organelles: mitochondria, rough endoplasmic reticulum, peroxisomes, autophagy, and aging, and can be influenced by exogenous factors: nutrition, physical activity, psychological status, environmental conditions, microbiome, and drugs.
Pedro Bullon, Francesca Giampieri, Beatriz Bullon, Maurizio Battino   +3 more
wiley   +1 more source

The Effect of Moringa oleifera's antibacterial and antibiofilm properties against Fusobacterium nucleatum and Staphylococcus aureus: a laboratory experiment

Padjadjaran Journal of Dentistry
Introduction: Fusobacterium nucleatum and Staphylococcus aureus, both associated with pulp and periapical diseases, must be effectively eliminated during irrigation.
Theodorus Aldo Fernando, Meiny Faudah Amin, ⁠Taufiq Ariwibowo, Ciptadhi Oka Binartha, Dikdik Kurnia   +4 more
doaj   +1 more source

NADH-dependent butanol dehydrogenase from Fusobacterium nucleatum: purification, crystallization, and X-ray crystallographic analysis

, 2022
Xue Bai, Jing Lan, Shanru He, Tingting Bu, Jie Zhang, Lulu Wang, Chunshan Quan, Ki Hyun Nam, Nam‐Chul Ha, Yongbin Xu   +9 more
openalex   +2 more sources

Inflammatory and Immunological Basis of Periodontal Diseases

Journal of Periodontal Research, EarlyView.
The periodontal lesion emerges as an evolving immunological battlefield, where host–microbiome interactions, dysregulated immune responses, fragile resolution mechanisms, and inflammophilic dysbiosis converge to shift the balance from homeostasis to unrestrained tissue destruction.
Giacomo Baima, Marion Arce, Mario Romandini, Thomas Van Dyke   +3 more
wiley   +1 more source

Fusobacterium nucleatum promotes colorectal carcinogenesis by modulating E-cadherin/β-catenin signaling via its FadA adhesin.

Cell Host and Microbe, 2013
M. R. Rubinstein, Xiaowei Wang, Wendy Liu, Yujun Hao, G. Cai, Yiping W Han   +5 more
semanticscholar   +1 more source

The Keystone‐Pathogen Hypothesis Updated: The Role of Porphyromonas gingivalis in Periodontitis

Journal of Periodontal Research, EarlyView.
Porphyromonas gingivalis orchestrates a coordinated manipulation of immune and inflammatory responses in periodontal tissues which leads to the generation of a dysbiotic, subgingival biofilm community, and progression of periodontitis. The type 9 secretion system, lipid A modification, and the formation of outer membrane vesicles are important ...
Mike A. Curtis, James A. Garnett, Richard P. Darveau   +2 more
wiley   +1 more source

Establishment and improvement of genetic manipulation tools for Fusobacterium nucleatum

Engineering Microbiology
An imbalance in oral microbial homeostasis is significantly associated with the onset and progression of several systemic diseases. Fusobacterium nucleatum, a ubiquitous periodontitis-causing bacterium in the oral cavity, is frequently detected in focal ...
Zhiwei Guan, Hailong Wang, Qiang Feng
doaj   +1 more source

Fusobacterium nucleatum Promotes Chemoresistance to Colorectal Cancer by Modulating Autophagy.

Cell, 2017
TaChung Yu, Fangfang Guo, Yanan Yu, T. Sun, Dangdang Ma, Ji-Xuan Han, Yun Qian, Ilona Kryczek, Danfeng Sun, N. Nagarsheth, Yingxuan Chen, Haoyan Chen, Jie Hong, W. Zou, J. Fang   +14 more
semanticscholar   +1 more source

Autoimmunity and Periodontitis

Journal of Periodontal Research, EarlyView.
In a microbe‐driven inflammatory environment, peptidyl‐arginine deiminase (PAD) enzymes from neutrophils and Porphyromonas gingivalis citrullinate both microbial and self‐antigens. B cell presentation of citrullinated or self‐mimicking epitopes activates T cells that assist B cells in antibody isotype switching, affinity maturation, epitope spreading ...
Massimo Costalonga, Vivek Thumbigere‐Math, Mark C. Herzberg   +2 more
wiley   +1 more source

The connection between Fusobacterium nucleatum levels and chemoresistance in colorectal cancer – a systematic review

Nowotwory
Introduction.The lack of response to chemotherapeutic drugs is one of the major challenges faced in the treatment of colorectal cancer. Several studies have indicated that the microbiome of the bowel affects the treatment response and specifically ...
Datis Kalali, Vasiliki Tzalili, Doxakis Anestakis   +2 more
doaj   +1 more source