Results 141 to 150 of about 28,141 (278)

Periodontitis and Diabetes: Mechanistic Evidence of a Circular Relationship

Journal of Periodontal Research, EarlyView.
This narrative review aimed to explore the underlying mechanisms that connect periodontitis to diabetes (and vice versa) and that influence disease susceptibility, progression and response to treatment. ABSTRACT The circular relationship between periodontitis and diabetes mellitus is one of the most established oral‐systemic links.
Philip M. Preshaw, Ren Jie Jacob Chew, Charlene Enhui Goh, Ali A. Abdulkareem, Dana T. Graves   +4 more
wiley   +1 more source

Periodontitis and Rheumatoid Arthritis—Mechanistic Evidence

Journal of Periodontal Research, EarlyView.
Periodontitis and rheumatoid arthritis are linked via the two‐hit model whereby early periodontal inflammation can lead to autoantibody production capable of interacting with inflamed synovial tissues. Subsequent systemic inflammation can exacerbate the periodontal inflammatory response and bacterial dysbiosis leading to further autoantibody production
Mark Bartold, Chia Wei Cheah, Rathna Devi Vaithilingam   +2 more
wiley   +1 more source

Fusobacterium nucleatum Promotes the Growth and Metastasis of Colorectal Cancer by Activating E‐Cadherin/Krüppel‐Like Factor 4/Integrin α5 Signaling in a Calcium‐Dependent Manner

MedComm
Gut microbiota and integrins are known to contribute to colorectal cancer (CRC), but whether they interact has been unclear. Here, we provided evidence that Fusobacterium nucleatum upregulated integrin α5 (ITGA5) in CRC in both human patients and murine ...
Xuebing Yan, Xiao Qu, Jiaxin Wang, Ling Lu, Wenjuan Wu, Jingxian Mao, Donglin Li, Ying Wang, Qing Wei, Jianqiang Liu   +9 more
doaj   +1 more source

Periodontitis and Adverse Pregnancy Outcomes: Mechanistic Evidence

Journal of Periodontal Research, EarlyView.
This narrative review aims to describe mechanisms linking periodontal diseases in pregnancy with adverse pregnancy outcomes. ABSTRACT Periodontal diseases, including both gingivitis and periodontitis, occur commonly among pregnant individuals. Both gingivitis and periodontitis are associated with adverse pregnancy outcomes (APOs) such as early ...
Gregory C. Valentine, Yiorgos A. Bobetsis, Benjamin C. Shayo, Peter Milgrom, Phoebus N. Madianos   +4 more
wiley   +1 more source

Fusobacterium nucleatum ¿Un patógeno periodontal promotor de carcinogénesis colorrectal?

, 2017
El Fusobacterium nucleatum es una bacteria anaerobia Gram negativa, es un residente común en el biofilm oral y se ha encontrado una estrecha asociación entre las fusobacterias y las periodontitis.
Zerón y Gutiérrez de Velasco, Agustín, Porras Lira, Davis   +1 more
core  

Next Generation Smart Implant Surfaces: Engineering Multifunctional Antimicrobial, Immunomodulatory and Regenerative Interfaces

Journal of Periodontal Research, EarlyView.
Natural‐inspired nano‐textured implant surfaces can be functionalised to modulate macrophage polarisation and local immune responses. This bioactive control promotes improved tissue integration and healing outcomes. ABSTRACT Dental implants rely on a stable and functional interface between the implant surface, surrounding tissues, and the oral ...
Roberto S. Pessoa, Lauren E. Steele, Mehvish Mumtaz, Denver P. Linklater, Neil M. O'Brien‐Simpson, Vladimir Baulin, Peter Kingshott, Roy Judge, Alastair J. Sloan, Elena P. Ivanova   +9 more
wiley   +1 more source

Saliva Liquid Biopsy for Detection of Oral and Systemic Diseases

Journal of Periodontal Research, EarlyView.
This Review summarizes and discusses the biological foundations and major classes of salivary biomarkers, outlines collection methods and analytical protocols for saliva‐based liquid biopsy, and technological convergences driven by multi‐omics approaches, artificial intelligence, and point‐of‐care devices in the application of oral and systemic ...
Irene Choi, Aaron Zander, Bradley Chan, Leila Syedmoradi, Dev Trivedi, Karolina Elżbieta Kaczor‐Urbanowicz, Fang Wei, Neeti Swarup, Trinity Chan, Mario Romandini, David T. W. Wong   +10 more
wiley   +1 more source

Comparative genome analysis of fusobacterium nucleatum

, 2016
Fusobacterium nucleatum is considered to be a key oral bacterium in recruiting periodontal pathogens into subgingival dental plaque. Currently F. Nucleatum can be subdivided into five subspecies. Our previous genome analysis of F.
Choo, S.W., Dutta, A., Wee, W.Y., Ang, M.Y., Dymock, D., Paterson, I.C.   +5 more
core   +1 more source

Fusobacterium nucleatum [PDF]

, 2020
openaire   +1 more source

The Dual Face of Fusobacterium nucleatum in Cancer: Foe, Friend or Both?

Journal of Periodontal Research, EarlyView.
Fusobacterium nucleatum has established interactions with cancers in humans. However, contrary to a traditional view that these interactions are uniformly pro‐tumoural, recent evidence suggests a more nuanced role, where contact‐dependent and contact‐independent mechanisms may support either tumour progression or restriction depending on tumour site ...
Anjali Chander, Huile Lim, Gilad Bachrach, Miguel Reis Ferreira   +3 more
wiley   +1 more source