Fusobacterium nucleatum Enhances Intestinal Adaptation of Vibrio cholerae via Interspecies Biofilm Formation. [PDF]
Chen G, Chen J, Wang X, Guo D, Liu Z.
europepmc +1 more source
MYC in Oncogenesis and Therapeutic Implications
The MYC oncogene family (c‐MYC, N‐MYC, L‐MYC) functions as a central transcriptional hub orchestrating cancer progression through multiple interconnected pathways. This graphical abstract illustrates MYC's role as a multidimensional regulator positioned at the nexus of tumor microenvironment remodeling, metabolic reprogramming, and therapeutic ...
Na Zhang +5 more
wiley +1 more source
Beyond a single species: Mapping virulence traits across the redefined <i>Fusobacterium nucleatum</i> complex. [PDF]
Wolf M +7 more
europepmc +1 more source
Proteomic Changes in Cancer Cell Lines as a Result of Bacterial Infection
ABSTRACT Bacterial infections have been implicated in shaping the tumor microenvironment (TME), but their effects on cancer cell proteomes remain unexplored. In this study, we analyzed proteomic changes in melanoma (A375) and ovarian cancer (OVCAR3) cell line models following infection with Staphylococcus aureus strain USA300 or Salmonella enterica ...
Bo Ren +7 more
wiley +1 more source
Characterization of the OMP biogenesis machinery in Fusobacterium nucleatum. [PDF]
Cottom CO +5 more
europepmc +1 more source
ABSTRACT The aim of this study was to synthesize evidence on the influence of Enterococcus faecalis on endodontic treatment failure and strategies for its elimination. This study followed the Preferred Reporting Items for Systematic Reviews and Meta‐Analyses (PRISMA) guidelines and was registered in PROSPERO (CRD420251022741).
Francine Santos Fernandes de Lima +1 more
wiley +1 more source
The role of <i>Fusobacterium nucleatum</i> in the tumour microenvironment and carcinogenesis of oral and colonic malignancies. [PDF]
Larionova E, Moran GP.
europepmc +1 more source
Gasdermin‐Mediated Pyroptosis: Novel Strategies Against Colorectal Cancer
Pyroptosis is a double‐edged sword in colorectal cancer (CRC): chronic low‐grade pyroptosis promotes tumor progression, whereas acute induction of pyroptosis in cancer cells triggers antitumor immunity and enhances therapeutic response. Targeting gasdermin‐mediated pyroptosis represents a promising strategy for CRC treatment.
Kaibo Guo +6 more
wiley +1 more source
Reprogramming of pathogenic strategies in <i>Fusobacterium nucleatum</i>: a study based on an <i>in vitro</i> infection model. [PDF]
Ma L +6 more
europepmc +1 more source
ABSTRACT Aim This cross‐sectional study aimed to compare the endodontic microbiome assessed from root canals of teeth associated with either symptomatic or asymptomatic apical periodontitis and analysed by 16S rDNA gene sequencing. Methodology 60 teeth presenting clinical and radiographic signs of symptomatic or asymptomatic apical periodontitis (n ...
David Donnermeyer +9 more
wiley +1 more source

