Results 131 to 140 of about 28,141 (278)

Periodontal Medicine Rewired: Mechanisms Linking Periodontitis to Systemic Diseases

Journal of Periodontal Research, EarlyView.
This review reorganizes decades of research in periodontal medicine into a multi‐dimensional framework, illustrating how periodontitis influences systemic health through at least seven interconnected mechanisms. ABSTRACT Periodontitis is now recognized not merely as a localized oral condition but as a systemic disease linked to over 70 communicable and
Mario Romandini, George Hajishengallis, Mike Curtis, Giacomo Baima   +3 more
wiley   +1 more source

The Oral‐Gut Axis: Bidirectional Interactions Between Microbiome and Diseases

Journal of Periodontal Research, EarlyView.
This study aims to summarize the mechanisms underlying ectopic colonization of the gut by oral pathobionts and the microbial and host factors that regulate this process. ABSTRACT Increased colonization of typically oral microorganisms is frequently observed in the gut mucosa or lumen of individuals with gastrointestinal disorders, including patients ...
Shinya Ebihara, Nobuhiko Kamada
wiley   +1 more source

Draft genome sequence of Fusobacterium nucleatum subsp. fusiforme ATCC 51190T

, 2012
Fusobacterium nucleatum, one of the major causative bacteria of periodontitis, is classified into five subspecies (nucleatum, polymorphum, vincentii, animalis, and fusiforme) on the basis of the several phenotypic characteristics and DNA homology.
S N Park, Y K Lim, M S Park, Sang-Haeng Choi, M H Choi, J K Kook, J W Lee, J H Shin, Hong-Seog Park, Young Hyo Chang, E Cho, S W Kong, H S Kim   +12 more
core   +1 more source

Periodontitis and Inflammatory Bowel Diseases: Mechanistic Evidence

Journal of Periodontal Research, EarlyView.
This review aims to provide a conceptual framework for understanding the mechanistic interplay between periodontitis and IBD, with a particular emphasis on the microbial and immunological crosstalk linking the oral cavity and the gastrointestinal tract.
Ana Paula V. Colombo, Adriana M. de Oliveira, Nobuhiko Kamada, Sho Kitamoto   +3 more
wiley   +1 more source

Abstract 4930: Genetic and epigenetic characteristics of esophageal cancer tissues with microbiome fusobacterium nucleatum

, 2017
Background: Research into the microbiome is a rapidly advancing field in human cancers. The gut microbiome has recently been shown to play an important role in health, as well as in diseases such as obesity, inflammatory bowel disease, diabetes, non ...
Kensuke Yamamura, Shigeki Nakagawa, Yoshifumi Baba, Hideo Baba, Masaaki Iwatsuki, Yasuo Sakamoto, Naoya Yoshida, Kosuke Mima, Takatsugu Ishimoto   +8 more
core   +1 more source

Osteoporosis and Periodontitis: Two‐Way Epidemiological and Mechanistic Evidence

Journal of Periodontal Research, EarlyView.
This review investigates the main mechanistic pathways connecting local periodontitis to systemic osteoporosis. Seven interconnected mechanisms are identified. ABSTRACT Osteoporosis and periodontitis are highly prevalent, chronic inflammatory diseases that constitute a major global health burden.
Jia Chang, Geeta Madhuri Bhuvanagiri, Megan Dulkanchainun, Cunyu Wang   +3 more
wiley   +1 more source

Fusobacterium nucleatum in colorectal cancer

Eurasian Journal of Applied Biotechnology
Background: Colorectal cancer is one of the most significant oncological diseases in the world due to its high morbidity and mortality. Fusobacterium nucleatum is an anaerobic bacterium that is actively studied in the context of colon carcinogenesis, since abundant seeding with this infection is observed in tumor tissues.
Gulmira Kulmambetova, Botakoz Kurentay, Dina Bayanbek, Alua Gusmaulemova   +3 more
openaire   +1 more source

Fusobacterium nucleatum regulation of neutrophil transcription

, 2011
Wright HJ, Chapple ILC, Matthews JB, Cooper PR. Fusobacterium nucleatum regulation of neutrophil transcription. J Periodont Res 2010; doi: 10.1111/j.1600-0765.2010.01299.x.
Chapple, Iain; id_orcid, I. L. C. Chapple, Matthews, John, H. J. Wright, Wright, Helen, J. B. Matthews, P. R. Cooper, Cooper, Paul   +7 more
core   +1 more source

Oral Health, Periodontitis, and Respiratory Diseases: Biological Pathways

Journal of Periodontal Research, EarlyView.
This narrative review aims to provide a comprehensive update on the potential mechanisms by which poor oral health and periodontitis impact lung health, focusing on pneumonia, COPD, and asthma. ABSTRACT Poor oral hygiene and periodontitis influence lung diseases such as pneumonia, chronic obstructive pulmonary disease (COPD), COVID‐19, and asthma.
Raluca P. Vacaru, Andreea C. Didilescu, Frank A. Scannapieco   +2 more
wiley   +1 more source

Targeted elimination of Fusobacterium nucleatum alleviates periodontitis [PDF]

Background Fusobacterium nucleatum, a pathobiont in periodontal disease, contributes to alveolar bone destruction. We assessed the efficacy of a new targeted antimicrobial, FP-100, in eradicating F.
Nil Yakar, Kantarci, Alpdoğan, Shi, Wenyuan, Lujia Cen, Tsute Chen, He, Xuesong, Ozge Unlu, Xuesong He, Hastürk, Hatice, Chen, Tsute, Hatice Hasturk, Cen, Lujia, Wenyuan Shi, Ünlü, Özge, Alpdogan Kantarci, Yakar, Nil   +15 more
core   +1 more source