Results 91 to 100 of about 19,818,011 (289)
Structural biology of ferritin nanocages
FEBS Letters, EarlyView.Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley +1 more source
Universal Reason, Aporias and the Future of Literature
Revue LISA, 2004 Cet article s’intéresse aux arguments qui ont cours depuis les années 1980-1990 dans les débats au sein les universités américaines à propos du « politiquement correct » et de la « guerre des cultures ». L’argument qui revient constamment dans ces débats
Anthony Larson
doaj +1 more source
Mechanisms of IgE‐mediated food allergy and the role of allergen‐specific B cells
FEBS Letters, EarlyView.Food allergy arises when allergen‐specific B cells preferentially produce immunoglobulin E (IgE) antibodies against harmless foods. This article explains the mechanisms driving IgE‐mediated reactions, highlights the central role of these B cells, and discusses how natural tolerance (NT) and oral immunotherapy (OIT) can reshape allergic immune responses.
Juan‐Felipe López +2 more
wiley +1 more source
TapuyaDuring the COVID-19 pandemic, Brazil was the target of great international concern due to the policies adopted by the far-right government of President Jair Bolsonaro.
Rosana Castro
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Seminars in Nuclear Medicine, 1996 Within the next 20 years, nuclear medicine could become a major focus of medical practice and biomedical research as medicine enters a new age of certainty, in which surgery, radiation, and chemotherapy will only be used when a benefit is certain to result from the treatment.
openaire +2 more sources
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Visions profanes du futur de la mobilité spatiale
Temporalités, 2019 For the founding fathers of the social sciences, the future was key. Marx, Tarde, Durkheim, Weber address the question of Progress and long-term change in society.
Alexandre Rigal
doaj +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
“REDISCOVERY” OF KNOWLEDGE ABOUT THE FUTURE: PERSPECTIVES OF RUSSIA’S SECURITY UP TO 2050
Vestnik MGIMO-Universiteta, 2017 The article deals with the dynamics of knowledge about the future, factors that determine the need for its »rediscovery« today, among which: the transition of mankind to the dominance of non-linear development; the destruction by globalization of the ...
S. A. Kravchenko, A. I. Podberezkin
doaj +1 more source
Structural insights into an engineered feruloyl esterase with improved MHET degrading properties
FEBS Letters, EarlyView.A feruloyl esterase was engineered to mimic key features of MHETase, enhancing the degradation of PET oligomers. Structural and computational analysis reveal how a point mutation stabilizes the active site and reshapes the binding cleft, expading substrate scope.
Panagiota Karampa +5 more
wiley +1 more source