Results 81 to 90 of about 53,164 (268)
Hyperosmotic stress induces PARP1‐mediated HPF1‐dependent mono(ADP‐ribosyl)ation
FEBS Letters, EarlyView.Sorbitol‐induced hyperosmotic stress rapidly induces reversible mono(ADP‐ribosyl)ation (MARylation) on PARP1 without the signs of genotoxic signaling. We show that PARP1 autoMARylation is HPF1 dependent and forms hydroxylamine‐resistant O‐glycosidic linkages.
Anna Georgina Kopasz +11 more
wiley +1 more source
Futures Studies, Mobilities, and the Postdigital Condition: Contention or Complement. [PDF]
Postdigit Sci Educ, 2022 Traxler J +3 more
europepmc +1 more source
Museum futures and other heritage futures
Over more than a century of museum and heritage practices, it has been maintained that we need to protect and preserve the past for the benefit of future generations.
Holtorf, Cornelius,, Högberg, Anders,
core +1 more source
Understanding the Breadth of Futures Studies through a Dialogue with Climate Change
, 2022 This article explores the breadth of the futures studies field by creating a dialogue with some prominent approaches to climate change. The first half of the article takes an evolutionary perspective on the development of the futures studies field.
Gidley, JM
core +1 more source
The ubiquitin ligase RNF115 is required for the clearance of damaged lysosomes
FEBS Letters, EarlyView.Upon lysosomal rupture, an E3 ubiquitin ligase RNF115 translocates from the cytosol to the damaged lysosomal membrane. Moreover, RNF115 depletion impairs the clearance of damaged lysosomes, identifying it as a key regulator of lysosomal quality control.
Sae Nakanaga +3 more
wiley +1 more source
Public acceptance of various ways to use and treat AI: A predictive moral framework
Computers in Human Behavior: Artificial HumansAs artificial intelligence rapidly transforms society, understanding the psychological principles that drive public acceptance or resistance is a critical challenge. Our study (U.S.
Kimmo Eriksson +3 more
doaj +1 more source
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
The price of accountability: corruption erodes social trust more in democracies than in autocracies
Frontiers in Political ScienceIntroductionWhile corruption exists in both democracies and autocracies, its social consequences may differ fundamentally across regime types. Democratic norms of equality and impartiality make trust highly sensitive to institutional failure. We theorize
Kimmo Eriksson +2 more
doaj +1 more source
Unpacking aviation travel futures : an application of causal layered analysis
, 2002 An overview of the issues influencing and driving aviation futures, and a critique of such futures, are provided. Air travel has been predicted to grow substantially in the decades ahead, as reflected in scenarios linked to the globalisation of tourism ...
May, Murray (S27242), Hill, Stuart B.
core
pH‐mediated activation of the lysosomal arginine sensor SLC38A9
FEBS Letters, EarlyView.Cells monitor nutrient levels via the lysosomal transporter SLC38A9 to activate the mechanistic target of rapamycin complex 1 (mTORC1). This study reveals that SLC38A9 function is regulated by pH. We identified histidine 544 as a critical pH sensor that undergoes conformational changes to control amino acid efflux from lysosomes; therefore, it ...
Xuelang Mu, Ampon Sae Her, Tamir Gonen
wiley +1 more source